World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
79
Citations
40022
World Ranking
4200
National Ranking
2054

Medicine

D-Index
79
Citations
40159
World Ranking
17350
National Ranking
8693

Overview

Hua Yu is affiliated with the City Of Hope National Medical Center in the United States. Their research spans multiple areas within medicine and biochemistry, genetics, and molecular biology. A significant body of their work focuses on oncology, molecular biology, and immunology, with notable contributions to cancer research and hematology.

The scientist has contributed to various key topics in their field, including:

  • Immune Cell Function and Interaction
  • Hemophilia Treatment and Research
  • PARP inhibition in cancer therapy
  • Cytokine Signaling Pathways and Interactions
  • Cancer Immunotherapy and Biomarkers
  • Cancer, Hypoxia, and Metabolism
  • RNA modifications and cancer

Hua Yu has a record of publications in important medical and scientific journals. Frequent publication venues include:

  • Frontiers in Oncology
  • Molecular Therapy - Nucleic Acids
  • Blood
  • Journal for ImmunoTherapy of Cancer
  • Cancer Research

Their research collaborations feature several frequent coauthors, notably:

  • Antons Martincuks
  • Yijia Li
  • Qianqian Zhao
  • Lorna Rodrı́guez-Rodrı́guez
  • Chunyan Zhang

Among recent publications attributed to Hua Yu's circle of research are:

  • STAT proteins in cancer: orchestration of metabolism, 2023, Nature reviews. Cancer
  • Two-Year Outcomes of Valoctocogene Roxaparvovec Therapy for Hemophilia A, 2023, New England Journal of Medicine
  • Cell-Free DNA: Hope and Potential Application in Cancer, 2021, Frontiers in Cell and Developmental Biology
  • Inhibition of the CDK2 and Cyclin A complex leads to autophagic degradation of CDK2 in cancer cells, 2022, Nature Communications
  • Fatty acid oxidation protects cancer cells from apoptosis by increasing mitochondrial membrane lipids, 2022, Cell Reports

Best Publications

  • STATs in cancer inflammation and immunity: a leading role for STAT3

    Hua Yu;Drew Pardoll;Richard Jove

  • The STATs of cancer — new molecular targets come of age

    Hua Yu;Richard Jove

  • Revisiting STAT3 signalling in cancer: new and unexpected biological functions

    Hua Yu;Heehyoung Lee;Andreas Herrmann;Ralf Buettner

  • Crosstalk between cancer and immune cells: role of STAT3 in the tumour microenvironment.

    Hua Yu;Marcin Kortylewski;Drew Pardoll

  • Constitutive Stat3 activity up-regulates VEGF expression and tumor angiogenesis

    Guilian Niu;Kenneth L Wright;Mei Huang;Lanxi Song

  • Regulation of the innate and adaptive immune responses by Stat-3 signaling in tumor cells.

    Tianhong Wang;Guilian Niu;Marcin Kortylewski;Lyudmila Burdelya

  • Inhibiting Stat3 signaling in the hematopoietic system elicits multicomponent antitumor immunity.

    Marcin Kortylewski;Maciej Kujawski;Tianhong Wang;Sheng Wei

  • Constitutive activation of Stat3 by the Src and JAK tyrosine kinases participates in growth regulation of human breast carcinoma cells.

    Roy Garcia;Tammy L Bowman;Guilian Niu;Hua Yu

  • IL-17 can promote tumor growth through an IL-6–Stat3 signaling pathway

    Lin Wang;Tangsheng Yi;Marcin Kortylewski;Drew M. Pardoll

  • Persistently Activated Stat3 Maintains Constitutive NF-κB Activity in Tumors

    Heehyoung Lee;Andreas Herrmann;Jie Hui Deng;Maciej Kujawski

  • Targeting Stat3 blocks both HIF-1 and VEGF expression induced by multiple oncogenic growth signaling pathways

    Qing Xu;Jon Briggs;Sungman Park;Guilian Niu

  • Cutting Edge: An In Vivo Requirement for STAT3 Signaling in TH17 Development and TH17-Dependent Autoimmunity

    Timothy J. Harris;Joseph F. Grosso;Hung Rong Yen;Hong Xin

  • Sunitinib Inhibition of Stat3 Induces Renal Cell Carcinoma Tumor Cell Apoptosis and Reduces Immunosuppressive Cells

    Hong Xin;Chunyan Zhang;Andreas Herrmann;Yan Du

  • JAK/STAT3-Regulated Fatty Acid β-Oxidation Is Critical for Breast Cancer Stem Cell Self-Renewal and Chemoresistance.

    Tianyi Wang;Tianyi Wang;Johannes Francois Fahrmann;Heehyoung Lee;Yi Jia Li

  • Stat3 mediates myeloid cell-dependent tumor angiogenesis in mice.

    Maciej Kujawski;Marcin Kortylewski;Heehyoung Lee;Andreas Herrmann

  • The JAK2 Inhibitor AZD1480 Potently Blocks Stat3 Signaling and Oncogenesis in Solid Tumors

    Michael Hedvat;Dennis Huszar;Andreas Herrmann;Joseph M. Gozgit

  • Regulation of the IL-23 and IL-12 balance by Stat3 signaling in the tumor microenvironment.

    Marcin Kortylewski;Hong Xin;Maciej Kujawski;Heehyoung Lee

  • Roles of activated Src and Stat3 signaling in melanoma tumor cell growth

    Guilian Niu;Tammy Bowman;Mei Huang;Steve Shivers

  • Role of Stat3 in Regulating p53 Expression and Function

    Guilian Niu;Kenneth L. Wright;Yihong Ma;Gabriela M. Wright

  • A Critical Role for Stat3 Signaling in Immune Tolerance

    Fengdong Cheng;Hong-Wei Wang;Alex Cuenca;Mei Huang

Frequent Co-Authors

Richard Jove
Richard Jove Nova Southeastern University
Stephen J. Forman
Stephen J. Forman City Of Hope National Medical Center
William S. Dalton
William S. Dalton University of South Florida
Robert A. Figlin
Robert A. Figlin Cedars-Sinai Medical Center
Drew M. Pardoll
Drew M. Pardoll Johns Hopkins University School of Medicine
Shumin M. Zhang
Shumin M. Zhang Brigham and Women's Hospital
Dave S.B. Hoon
Dave S.B. Hoon St. John's University
Thomas Blankenstein
Thomas Blankenstein Max Delbrück Center for Molecular Medicine
Richard Heller
Richard Heller University of South Florida
George Somlo
George Somlo City Of Hope National Medical Center

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Best Scientists Citing Hua Yu

Trending Scientists

Recently Published Articles