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Best Scientists
2025
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Immunology
USA
2026

D-Index & Metrics

Best Scientists

D-Index
169
Citations
175422
World Ranking
887
National Ranking
528

Immunology

D-Index
173
Citations
186974
World Ranking
47
National Ranking
34

Medicine

D-Index
173
Citations
187094
World Ranking
460
National Ranking
273

Research.com Recognitions

  • 2026 - Research.com Immunology in United States Leader Award
  • 2025 - Research.com Best Scientists Award
  • 2025 - Research.com Immunology in United States Leader Award
  • 2018 - Fellow, National Academy of Inventors
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians

Overview

Drew M. Pardoll is affiliated with Johns Hopkins University School of Medicine in the United States. Their research spans several fields of study, primarily in medicine, biochemistry, genetics and molecular biology, and immunology and microbiology. Within these broad areas, their work focuses heavily on oncology, immunology, molecular biology, pulmonary and respiratory medicine, and cancer research.

The main topics covered in their research include:

  • Cancer Immunotherapy and Biomarkers
  • CAR-T cell therapy research
  • Immunotherapy and Immune Responses
  • Immune cells in cancer
  • Immune Cell Function and Interaction
  • Single-cell and spatial transcriptomics
  • Cancer Genomics and Diagnostics

The scientist has published in a variety of venues with frequent contributions to:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Cancer Research
  • Regular and Young Investigator Award Abstracts
  • Nature Medicine
  • Nature Communications

Notable recent papers authored or co-authored by Drew M. Pardoll include:

  • Neoadjuvant checkpoint blockade for cancer immunotherapy, 2020, Science
  • Transcriptional programs of neoantigen-specific TIL in anti-PD-1-treated lung cancers, 2021, Nature
  • Conserved Interferon-γ Signaling Drives Clinical Response to Immune Checkpoint Blockade Therapy in Melanoma, 2020, Cancer Cell
  • Epigenetic therapy inhibits metastases by disrupting premetastatic niches, 2020, Nature
  • Targeting a neoantigen derived from a common TP53 mutation, 2021, Science

Collaboration is a significant aspect of Drew M. Pardoll's research activity. Frequent co-authors include:

  • Kellie N. Smith
  • Ada Tam
  • Franck Housseau
  • Janis M. Taube
  • Patrick M. Forde

Drew M. Pardoll has been recognized by various professional organizations, including being named a Fellow of the National Academy of Inventors in 2018 and holding membership in the Association of American Physicians.

Best Publications

  • The blockade of immune checkpoints in cancer immunotherapy

    Drew M. Pardoll

  • Safety, activity, and immune correlates of anti-PD-1 antibody in cancer.

    Suzanne L. Topalian;F. Stephen Hodi;Julie R. Brahmer;Scott N. Gettinger

  • PD-1 Blockade in Tumors with Mismatch-Repair Deficiency

    Dung T. Le;Jennifer N. Uram;Hao Wang;Bjarne R. Bartlett

  • Safety and Activity of Anti–PD-L1 Antibody in Patients with Advanced Cancer

    Julie R. Brahmer;Scott S. Tykodi;Scott S. Tykodi;Laura Q.M. Chow;Wen Jen Hwu

  • Mismatch repair deficiency predicts response of solid tumors to PD-1 blockade

    Dung T. Le;Dung T. Le;Jennifer N. Durham;Jennifer N. Durham;Kellie N. Smith;Hao Wang

  • STATs in cancer inflammation and immunity: a leading role for STAT3

    Hua Yu;Drew Pardoll;Richard Jove

  • Immune checkpoint blockade: a common denominator approach to cancer therapy

    Suzanne L. Topalian;Charles G. Drake;Drew M. Pardoll

  • Phase I Study of Single-Agent Anti–Programmed Death-1 (MDX-1106) in Refractory Solid Tumors: Safety, Clinical Activity, Pharmacodynamics, and Immunologic Correlates

    Julie R. Brahmer;Charles G. Drake;Ira Wollner;John D. Powderly

  • Mechanism-driven biomarkers to guide immune checkpoint blockade in cancer therapy

    Suzanne L. Topalian;Janis M. Taube;Robert A. Anders;Drew M. Pardoll

  • Survival, Durable Tumor Remission, and Long-Term Safety in Patients With Advanced Melanoma Receiving Nivolumab

    Suzanne L. Topalian;Mario Sznol;David F. McDermott;Harriet M. Kluger

  • Association of PD-1, PD-1 ligands, and other features of the tumor immune microenvironment with response to anti-PD-1 therapy

    Janis M Taube;Alison P. Klein;Julie R Brahmer;Haiying Xu

  • Colocalization of Inflammatory Response with B7-H1 Expression in Human Melanocytic Lesions Supports an Adaptive Resistance Mechanism of Immune Escape

    Janis M. Taube;Robert A. Anders;Geoffrey D. Young;Haiying Xu

  • Crosstalk between cancer and immune cells: role of STAT3 in the tumour microenvironment.

    Hua Yu;Marcin Kortylewski;Drew Pardoll

  • Neoadjuvant PD-1 Blockade in Resectable Lung Cancer

    Patrick M. Forde;Jamie E. Chaft;Kellie N. Smith;Valsamo Anagnostou

  • Inhibiting DNA Methylation Causes an Interferon Response in Cancer via dsRNA Including Endogenous Retroviruses

    Katherine B. Chiappinelli;Pamela L. Strissel;Alexis Desrichard;Huili Li

  • A human colonic commensal promotes colon tumorigenesis via activation of T helper type 17 T cell responses

    Shaoguang Wu;Ki Jong Rhee;Ki Jong Rhee;Ki Jong Rhee;Emilia Albesiano;Shervin Rabizadeh

  • Immune Inhibitory Molecules LAG-3 and PD-1 Synergistically Regulate T-cell Function to Promote Tumoral Immune Escape

    Seng Ryong Woo;Meghan E Turnis;Monica V Goldberg;Jaishree Bankoti

  • Control of TH17/Treg Balance by Hypoxia-Inducible Factor 1

    Eric V. Dang;Joseph Barbi;Huang Yu Yang;Huang Yu Yang;Dilini Jinasena

  • The Central Role of CD4+ T Cells in the Antitumor Immune Response

    Kenneth Hung;Robert Hayashi;Anne Lafond-Walker;Charles Lowenstein

  • Targeting the PD-1/B7-H1(PD-L1) pathway to activate anti-tumor immunity.

    Suzanne L Topalian;Charles G Drake;Drew M Pardoll

  • Constitutive Stat3 activity up-regulates VEGF expression and tumor angiogenesis

    Guilian Niu;Kenneth L Wright;Mei Huang;Lanxi Song

Frequent Co-Authors

Franck Housseau
Franck Housseau Johns Hopkins University School of Medicine
Charles G. Drake
Charles G. Drake Columbia University
Janis M. Taube
Janis M. Taube Johns Hopkins University
Elizabeth M. Jaffee
Elizabeth M. Jaffee Johns Hopkins University
Suzanne L. Topalian
Suzanne L. Topalian Johns Hopkins University
Robert A. Anders
Robert A. Anders Johns Hopkins University School of Medicine
Jennifer H. Elisseeff
Jennifer H. Elisseeff Johns Hopkins University
Henry Brem
Henry Brem Johns Hopkins University School of Medicine
Lieping Chen
Lieping Chen Yale University
Hua Yu
Hua Yu City Of Hope National Medical Center

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