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Immunology

D-Index
50
Citations
21814
World Ranking
4179
National Ranking
1905

Overview

Franck Housseau is affiliated with Johns Hopkins University School of Medicine in the United States. Their research spans across multiple fields within medicine and biochemistry, genetics, and molecular biology, with notable focus areas including molecular biology, immunology, oncology, infectious diseases, and epidemiology.

Their main fields of study include:

  • Medicine
  • Biochemistry, Genetics and Molecular Biology

Within these fields, they have concentrated on several subfields of study:

  • Molecular Biology
  • Immunology
  • Oncology
  • Infectious Diseases
  • Epidemiology

Key research topics explored by Franck Housseau include:

  • Gut microbiota and health
  • Cancer Immunotherapy and Biomarkers
  • Clostridium difficile and Clostridium perfringens research
  • Immune cells in cancer
  • Inflammatory Bowel Disease
  • Telomeres, Telomerase, and Senescence
  • Single-cell and spatial transcriptomics

Recent publications by Franck Housseau feature the following papers:

  • Epigenetic therapy inhibits metastases by disrupting premetastatic niches, 2020, published in Nature
  • IL-17 and immunologically induced senescence regulate response to injury in osteoarthritis, 2020, Journal of Clinical Investigation
  • Interleukin 17 and senescent cells regulate the foreign body response to synthetic material implants in mice and humans, 2020, Science Translational Medicine
  • Human Colon Cancer-Derived Clostridioides difficile Strains Drive Colonic Tumorigenesis in Mice, 2022, Cancer Discovery
  • Pathways of immune exclusion in metastatic osteosarcoma are associated with inferior patient outcomes, 2021, Journal for ImmunoTherapy of Cancer

Frequent publication venues for their work include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Regular and Young Investigator Award Abstracts
  • Gastroenterology
  • Cancer Discovery
  • Proceedings of the National Academy of Sciences

Franck Housseau has collaborated regularly with several co-authors, including:

  • Drew M. Pardoll
  • Ada Tam
  • Cynthia L. Sears
  • Jennifer H. Elisseeff
  • Joscelyn C. Mejías

Best Publications

  • Mismatch repair deficiency predicts response of solid tumors to PD-1 blockade

    Dung T. Le;Dung T. Le;Jennifer N. Durham;Jennifer N. Durham;Kellie N. Smith;Hao Wang

  • A human colonic commensal promotes colon tumorigenesis via activation of T helper type 17 T cell responses

    Shaoguang Wu;Ki Jong Rhee;Ki Jong Rhee;Ki Jong Rhee;Emilia Albesiano;Shervin Rabizadeh

  • The Vigorous Immune Microenvironment of Microsatellite Instable Colon Cancer Is Balanced by Multiple Counter-Inhibitory Checkpoints

    Nicolas J. Llosa;Michael Cruise;Ada Tam;Elizabeth C. Wicks

  • Cutting Edge: An In Vivo Requirement for STAT3 Signaling in TH17 Development and TH17-Dependent Autoimmunity

    Timothy J. Harris;Joseph F. Grosso;Hung Rong Yen;Hong Xin

  • Developing a pro-regenerative biomaterial scaffold microenvironment requires T helper 2 cells.

    Kaitlyn Sadtler;Kaitlyn Sadtler;Kenneth Estrellas;Kenneth Estrellas;Brian W. Allen;Brian W. Allen;Matthew T. Wolf;Matthew T. Wolf

  • Bacteroides fragilis Toxin Coordinates a Pro-carcinogenic Inflammatory Cascade via Targeting of Colonic Epithelial Cells.

    Liam Chung;Erik Thiele Orberg;Abby L. Geis;June L. Chan

  • Interferon-producing killer dendritic cells provide a link between innate and adaptive immunity.

    Camie W. Chan;Emily Crafton;Hong Ni Fan;James Flook

  • Oncogenic Kras Activates a Hematopoietic-to-Epithelial IL-17 Signaling Axis in Preinvasive Pancreatic Neoplasia

    Florencia McAllister;Jennifer M. Bailey;Janivette Alsina;Christopher J. Nirschl

  • Bacteroides fragilis subverts mucosal biology: from symbiont to colon carcinogenesis

    Cynthia L. Sears;Abby L. Geis;Franck Housseau

  • Key players in the immune response to biomaterial scaffolds for regenerative medicine.

    Liam Chung;David R. Maestas;Franck Housseau;Jennifer H. Elisseeff

  • Epigenetic therapy inhibits metastases by disrupting premetastatic niches

    Zhihao Lu;Zhihao Lu;Zhihao Lu;Jianling Zou;Shuang Li;Michael J. Topper

  • Induction of Persistent Colitis by a Human Commensal, Enterotoxigenic Bacteroides fragilis, in Wild-Type C57BL/6 Mice

    Ki Jong Rhee;Shaoguang Wu;Xinqun Wu;David L. Huso

  • CD40-stimulated B lymphocytes pulsed with tumor antigens are effective antigen-presenting cells that can generate specific T cells.

    Réjean Lapointe;Angélique Bellemare-Pelletier;Franck Housseau;Jacques Thibodeau

  • Divergent immune responses to synthetic and biological scaffolds.

    Kaitlyn Sadtler;Matthew T. Wolf;Sudipto Ganguly;Christopher A. Moad

  • IL-17 and immunologically induced senescence regulate response to injury in osteoarthritis.

    Heather J. Faust;Hong Zhang;Jin Han;Matthew T. Wolf

  • Cooperative B7-1/2 (CD80/CD86) and B7-DC Costimulation of CD4+ T Cells Independent of the PD-1 Receptor

    Tahiro Shin;Gene Kennedy;Kevin Gorski;Haruo Tsuchiya

  • The myeloid immune signature of enterotoxigenic Bacteroides fragilis-induced murine colon tumorigenesis.

    E Thiele Orberg;H Fan;A J Tam;C M Dejea

  • In vivo costimulatory role of B7-DC in tuning T helper cell 1 and cytotoxic T lymphocyte responses

    Tahiro Shin;Kiyoshi Yoshimura;Takako Shin;Emily B. Crafton

  • Regulatory T-cell Response to Enterotoxigenic Bacteroides fragilis Colonization Triggers IL17-Dependent Colon Carcinogenesis

    Abby L. Geis;Hongni Fan;Xinqun Wu;Shaoguang Wu

  • Interleukin 17 and Senescent Cells Regulate the Foreign Body Response to Synthetic Material Implants in Mice and Humans

    Liam Chung;Liam Chung;David R. Maestas;Andriana Lebid;Ashlie Mageau

  • Contrasting patterns of regulation of the antioxidant selenoproteins, thioredoxin reductase, and glutathione peroxidase, in cancer cells

    Vadim N. Gladyshev;Vadim N. Gladyshev;Valentina M. Factor;Franck Housseau;Dolph L. Hatfield

Frequent Co-Authors

Drew M. Pardoll
Drew M. Pardoll Johns Hopkins University School of Medicine
Cynthia L. Sears
Cynthia L. Sears Johns Hopkins University
Robert A. Anders
Robert A. Anders Johns Hopkins University School of Medicine
Jennifer H. Elisseeff
Jennifer H. Elisseeff Johns Hopkins University
David L. Huso
David L. Huso Johns Hopkins University
Janis M. Taube
Janis M. Taube Johns Hopkins University
Kenneth W. Kinzler
Kenneth W. Kinzler Johns Hopkins University
Luis A. Diaz
Luis A. Diaz Memorial Sloan Kettering Cancer Center
Cynthia L. Sears
Cynthia L. Sears Johns Hopkins University School of Medicine
Bert Vogelstein
Bert Vogelstein Johns Hopkins University

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