World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
70
Citations
14991
World Ranking
7123
National Ranking
521

Overview

Matthias Kloor is affiliated with the University Hospital Heidelberg in Germany and has an extensive publication record in the fields of medicine, biochemistry, genetics, and molecular biology. Their research primarily focuses on oncology, pathology, forensic medicine, cancer research, molecular biology, and surgery.

Their work covers several main topics, notably genetic factors in colorectal cancer, cancer genomics and diagnostics, colorectal cancer screening and detection, cancer immunotherapy and biomarkers, colorectal cancer treatments and studies, multiple and secondary primary cancers, and colorectal and anal carcinomas.

Matthias Kloor has contributed to various research publications, including:

  • European guidelines from the EHTG and ESCP for Lynch syndrome: an updated third edition of the Mallorca guidelines based on gene and gender (2020), published in British Journal of Surgery
  • A Frameshift Peptide Neoantigen-Based Vaccine for Mismatch Repair-Deficient Cancers: A Phase I/IIa Clinical Trial (2020), published in Clinical Cancer Research
  • The shared frameshift mutation landscape of microsatellite-unstable cancers suggests immunoediting during tumor evolution (2020), published in Nature Communications
  • Variation in the risk of colorectal cancer in families with Lynch syndrome: a retrospective cohort study (2021), published in The Lancet Oncology
  • Recurrent Frameshift Neoantigen Vaccine Elicits Protective Immunity With Reduced Tumor Burden and Improved Overall Survival in a Lynch Syndrome Mouse Model (2021), published in Gastroenterology

Kloor collaborates frequently with several co-authors, including:

  • Aysel Ahadova (42 co-authored works)
  • Magnus von Knebel Doeberitz (36 co-authored works)
  • Hendrik Bläker (25 co-authored works)
  • Hermann Brenner (21 co-authored works)
  • Michael Hoffmeister (21 co-authored works)

Their research has been published in multiple venues, with frequent contributions to:

  • bioRxiv (Cold Spring Harbor Laboratory) (11 publications)
  • International Journal of Cancer (8 publications)
  • Gastroenterology (5 publications)
  • Frontiers in Oncology (4 publications)
  • Cancer Research (4 publications)

The scope of Matthias Kloor's work includes genetics and molecular mechanisms behind colorectal cancer, development of immunotherapeutic approaches, and diagnostic strategies for cancer detection and treatment. Their involvement in these complex topics contributes to ongoing efforts in understanding and managing colorectal and related cancers.

Best Publications

  • Potential of fecal microbiota for early‐stage detection of colorectal cancer

    Georg Zeller;Julien Tap;Anita Y Voigt;Shinichi Sunagawa

  • Localization and Density of Immune Cells in the Invasive Margin of Human Colorectal Cancer Liver Metastases Are Prognostic for Response to Chemotherapy

    Niels Halama;Sara Michel;Matthias Kloor;Inka Zoernig

  • Application of a 5-tiered scheme for standardized classification of 2,360 unique mismatch repair gene variants in the InSiGHT locus-specific database

    Bryony A Thompson;Bryony A Thompson;Amanda B Spurdle;John-Paul Plazzer;Marc S Greenblatt

  • Immune Response Against Frameshift-Induced Neopeptides in HNPCC Patients and Healthy HNPCC Mutation Carriers

    Yvette Schwitalle;Matthias Kloor;Susanne Eiermann;Michael Linnebacher

  • Natural killer cells are scarce in colorectal carcinoma tissue despite high levels of chemokines and cytokines.

    Niels Halama;Monika Braun;Christoph Kahlert;Anna Spille

  • Risk of colorectal and endometrial cancers in EPCAM deletion-positive Lynch syndrome: a cohort study

    Marlies J E Kempers;Roland P Kuiper;Charlotte W Ockeloen;Pierre O Chappuis

  • Microsatellite instability in colorectal cancer is associated with local lymphocyte infiltration and low frequency of distant metastases

    A. Buckowitz;H. P. Knaebel;A. Benner;H. Bläker

  • Immune Escape and Survival Mechanisms in Circulating Tumor Cells of Colorectal Cancer

    Gunnar Steinert;Sebastian Schölch;Thomas Niemietz;Naoki Iwata

  • The Immune Biology of Microsatellite-Unstable Cancer

    Matthias Kloor;Magnus von Knebel Doeberitz

  • Genotype-Phenotype Comparison of German MLH1 and MSH2 Mutation Carriers Clinically Affected With Lynch Syndrome: A Report by the German HNPCC Consortium

    Timm Goecke;Karsten Schulmann;Christoph Engel;Elke Holinski-Feder

  • Three molecular pathways model colorectal carcinogenesis in Lynch syndrome

    Aysel Ahadova;Aysel Ahadova;Aysel Ahadova;Richard Gallon;Johannes Gebert;Johannes Gebert;Johannes Gebert;Alexej Ballhausen;Alexej Ballhausen;Alexej Ballhausen

  • Recurrence and Variability of Germline EPCAM Deletions in Lynch Syndrome

    Roland P. Kuiper;Lisenka E. L. M. Vissers;Ramprasath Venkatachalam;Danielle Bodmer

  • Immunoselective Pressure and Human Leukocyte Antigen Class I Antigen Machinery Defects in Microsatellite Unstable Colorectal Cancers

    Matthias Kloor;Christina Becker;Axel Benner;Stefan M. Woerner

  • Tumor-infiltrating lymphocytes in colorectal tumors display a diversity of T cell receptor sequences that differ from the T cells in adjacent mucosal tissue.

    Anna M. Sherwood;Ryan O. Emerson;Dominique Scherer;Nina Habermann

  • Genetic evolution of T-cell resistance in the course of melanoma progression

    Antje Sucker;Fang Zhao;Birgit Real;Christina Heeke

  • Overexpression of ZEB2 at the Invasion Front of Colorectal Cancer Is an Independent Prognostic Marker and Regulates Tumor Invasion In Vitro

    Christoph Kahlert;Saleh Lahes;Praveen Radhakrishnan;Shamik Dutta

  • European guidelines from the EHTG and ESCP for Lynch syndrome: an updated third edition of the Mallorca guidelines based on gene and gender

    Toni T. Seppälä;Toni T. Seppälä;A. Latchford;A. Latchford;I. Negoi;A. Sampaio Soares

  • Immune evasion of microsatellite unstable colorectal cancers.

    Matthias Kloor;Sara Michel;Sara Michel;Magnus von Knebel Doeberitz;Magnus von Knebel Doeberitz

  • Colorectal mixed adenoneuroendocrine carcinomas and neuroendocrine carcinomas are genetically closely related to colorectal adenocarcinomas

    Moritz Jesinghaus;Björn Konukiewitz;Gisela Keller;Matthias Kloor

  • Somatic Hypermethylation of MSH2 Is a Frequent Event in Lynch Syndrome Colorectal Cancers

    Takeshi Nagasaka;Jennifer Rhees;Matthias Kloor;Johannes Gebert

Frequent Co-Authors

Magnus von Knebel Doeberitz
Magnus von Knebel Doeberitz Heidelberg University
Jenny Chang-Claude
Jenny Chang-Claude German Cancer Research Center
Peter Schirmacher
Peter Schirmacher University Hospital Heidelberg
Michael Hoffmeister
Michael Hoffmeister German Cancer Research Center
Hermann Brenner
Hermann Brenner German Cancer Research Center
Christoph Engel
Christoph Engel Leipzig University
Axel Benner
Axel Benner German Cancer Research Center
Albrecht Stenzinger
Albrecht Stenzinger Heidelberg University
Wolff Schmiegel
Wolff Schmiegel Ruhr University Bochum
Jürgen Weitz
Jürgen Weitz TU Dresden

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Exploring Biology and Biochemistry unlocks diverse career opportunities, many of which can be accessed through flexible online programs. For those interested in nutrition, a holistic nutrition degree can provide a valuable foundation for roles in wellness, community health, or private practice.

Students looking to enter the management side of healthcare may consider pursuing the cheapest online mba healthcare management program. This pathway prepares graduates for leadership positions in hospitals, clinics, and healthcare startups while helping to minimize tuition costs.

Alternatively, becoming a professional coder is a growing field for those with an eye for detail. Understanding the medical coding certification differences is critical, as certifications can impact job prospects and potential salaries.

If you’re curious about job stability and income, the medical.coder salary continues to be competitive, reflecting the healthcare industry's ongoing need for accurate record-keeping and compliance.

Whether you pursue advanced healthcare management, nutrition, or medical coding, the field offers multiple online pathways tailored to your career aspirations and budget.

Best Scientists Citing Matthias Kloor

Trending Scientists

Recently Published Articles