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Medicine

D-Index
91
Citations
32401
World Ranking
11708
National Ranking
635

Overview

Wolff Schmiegel is affiliated with Ruhr University Bochum in Germany and has contributed extensively to the field of medicine, particularly focusing on oncology and related subfields. Their research spans clinical and molecular aspects of cancer, with a significant emphasis on colorectal cancer and genetic factors influencing its development.

Schmiegel's work covers several main fields of study:

  • Medicine

Their subfields of expertise include:

  • Oncology
  • Pathology and Forensic Medicine
  • Cancer Research
  • Surgery
  • Molecular Biology

Key topics in Schmiegel's research involve:

  • Genetic factors in colorectal cancer
  • Cancer Genomics and Diagnostics
  • Colorectal Cancer Screening and Detection
  • Colorectal Cancer Treatments and Studies
  • Colorectal and Anal Carcinomas
  • Pancreatic and Hepatic Oncology Research
  • Multiple and Secondary Primary Cancers

The scientist has published in numerous academic venues, with frequent publications in:

  • International Journal of Cancer
  • Genetics in Medicine
  • Journal of Clinical Medicine
  • Molecular Oncology
  • Journal of Cancer Research and Clinical Oncology

Among Schmiegel's recent papers are:

  • Chemoradiotherapy Plus Induction or Consolidation Chemotherapy as Total Neoadjuvant Therapy for Patients With Locally Advanced Rectal Cancer, 2021, JAMA Oncology
  • Mortality by age, gene and gender in carriers of pathogenic mismatch repair gene variants receiving surveillance for early cancer diagnosis and treatment: a report from the prospective Lynch syndrome database, 2023, EClinicalMedicine
  • Cancer risks in Lynch syndrome, Lynch-like syndrome, and familial colorectal cancer type X: a prospective cohort study, 2020, BMC Cancer
  • Colorectal cancer incidences in Lynch syndrome: a comparison of results from the prospective lynch syndrome database and the international mismatch repair consortium, 2022, Hereditary Cancer in Clinical Practice
  • Risk-reducing hysterectomy and bilateral salpingo-oophorectomy in female heterozygotes of pathogenic mismatch repair variants: a Prospective Lynch Syndrome Database report, 2020, Genetics in Medicine

Frequent co-authors include:

  • Deepak Vangala
  • Stefan Aretz
  • Verena Steinke-Lange
  • Christoph Engel
  • Elke Holinski-Feder

Best Publications

  • Perioperative chemotherapy with fluorouracil plus leucovorin, oxaliplatin, and docetaxel versus fluorouracil or capecitabine plus cisplatin and epirubicin for locally advanced, resectable gastric or gastro-oesophageal junction adenocarcinoma (FLOT4): a randomised, phase 2/3 trial.

    Salah-Eddin Al-Batran;Nils Homann;Claudia Pauligk;Thorsten O Goetze

  • Oral Capecitabine Compared With Intravenous Fluorouracil Plus Leucovorin in Patients With Metastatic Colorectal Cancer: Results of a Large Phase III Study

    Eric Van Cutsem;Chris Twelves;Jim Cassidy;David Allman

  • Glucagon-like peptide 1 inhibition of gastric emptying outweighs its insulinotropic effects in healthy humans

    Michael A. Nauck;Ulrich Niedereichholz;Rainer Ettler;Jens Juul Holst

  • Randomised trial of monoclonal antibody for adjuvant therapy of resected Dukes' C colorectal carcinoma

    G. Riethmüller;R. Gruber;E. Schneider-Gädicke;G. Schlimok

  • Abrogation of the Rb/p16 Tumor-suppressive Pathway in Virtually All Pancreatic Carcinomas

    Mieke Schutte;Ralph H. Hruban;Joseph Geradts;Rob Maynard

  • Effects of Glucagon-Like Peptide 1 on Counterregulatory Hormone Responses, Cognitive Functions, and Insulin Secretion during Hyperinsulinemic, Stepped Hypoglycemic Clamp Experiments in Healthy Volunteers

    Michael A. Nauck;Markus M. Heimesaat;Kai Behle;Jens J. Holst

  • Monoclonal antibody therapy for resected Dukes' C colorectal cancer: seven-year outcome of a multicenter randomized trial.

    G Riethmüller;E Holz;G Schlimok;W Schmiegel

  • Histopathological regression after neoadjuvant docetaxel, oxaliplatin, fluorouracil, and leucovorin versus epirubicin, cisplatin, and fluorouracil or capecitabine in patients with resectable gastric or gastro-oesophageal junction adenocarcinoma (FLOT4-AIO): results from the phase 2 part of a multicentre, open-label, randomised phase 2/3 trial.

    Salah-Eddin Al-Batran;Ralf D Hofheinz;Claudia Pauligk;Hans-Georg Kopp

  • BRCA2 Germline Mutations in Familial Pancreatic Carcinoma

    Stephan A. Hahn;Bill Greenhalf;Ian Ellis;Mercedes Sina-Frey

  • European guidelines for quality assurance in colorectal cancer screening and diagnosis : Overview and introduction to the full Supplement publication.

    L. Von Karsa;J. Patnick;J. Patnick;N. Segnan;W. Atkin

  • Cancer risks by gene, age, and gender in 6350 carriers of pathogenic mismatch repair variants: findings from the Prospective Lynch Syndrome Database

    Mev Dominguez-Valentin;Julian R. Sampson;Toni T. Seppälä;Sanne W. ten Broeke

  • Oral capecitabine vs intravenous 5-fluorouracil and leucovorin: integrated efficacy data and novel analyses from two large, randomised, phase III trials

    E Van Cutsem;P M Hoff;P Harper;R M Bukowski

  • Randomized Phase II Trial of Chemoradiotherapy Plus Induction or Consolidation Chemotherapy as Total Neoadjuvant Therapy for Locally Advanced Rectal Cancer: CAO/ARO/AIO-12

    Emmanouil Fokas;Michael Allgäuer;Bülent Polat;Gunther Klautke

  • Smad4/DPC4-mediated tumor suppression through suppression of angiogenesis

    Irmgard Schwarte-Waldhoff;Olga V. Volpert;Noël P. Bouck;Bence Sipos

  • [Update S3-guideline "colorectal cancer" 2008].

    W. Schmiegel;A. Reinacher-Schick;D. Arnold;U. Graeven

  • Phase III Study of Capecitabine Plus Oxaliplatin Compared With Fluorouracil and Leucovorin Plus Oxaliplatin in Metastatic Colorectal Cancer: A Final Report of the AIO Colorectal Study Group

    Rainer Porschen;Hendrik Tobias Arkenau;Stephan Kubicka;Richard Greil

  • Identification of microRNAs in the cerebrospinal fluid as marker for primary diffuse large B-cell lymphoma of the central nervous system

    Alexander Baraniskin;Jan Kuhnhenn;Uwe Schlegel;Andrew Chan

  • Efficacy of a nationwide screening colonoscopy program for colorectal cancer.

    Christian P. Pox;Lutz Altenhofen;Hermann Brenner;Arno Theilmeier

  • Risks of Less Common Cancers in Proven Mutation Carriers With Lynch Syndrome

    Christoph Engel;Markus Loeffler;Verena Steinke;Nils Rahner

  • BRCA2 germline mutations in familial pancreatic carcinoma

    Stephan A. Hahn;Bill Greenhalf;Ellis Ian;Mercedes Sina-Frey

Frequent Co-Authors

Christoph Engel
Christoph Engel Leipzig University
Helmut E. Meyer
Helmut E. Meyer Ruhr University Bochum
Michael A. Nauck
Michael A. Nauck Ruhr University Bochum
Magnus von Knebel Doeberitz
Magnus von Knebel Doeberitz Heidelberg University
Bence Sipos
Bence Sipos University of Tübingen
Markus Loeffler
Markus Loeffler Leipzig University
Günter Klöppel
Günter Klöppel Technical University of Munich
Matthias Kloor
Matthias Kloor University Hospital Heidelberg
Jens J. Holst
Jens J. Holst University of Copenhagen
Hans-Joachim Schmoll
Hans-Joachim Schmoll Martin Luther University Halle-Wittenberg

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