Christoph Engel

Overview

Best Publications

• Intensive insulin therapy and pentastarch resuscitation in severe sepsis.

  Frank M. Brunkhorst;Christoph Engel;Frank Bloos;Andreas Meier-Hellmann

  3695
  Citations

• Risks of Breast, Ovarian, and Contralateral Breast Cancer for BRCA1 and BRCA2 Mutation Carriers

  Karoline B. Kuchenbaecker;Karoline B. Kuchenbaecker;John L. Hopper;Daniel R. Barnes;Kelly-Anne Phillips

  2526
  Citations

• Association analysis identifies 65 new breast cancer risk loci

  Kyriaki Michailidou;Kyriaki Michailidou;Sara Lindström;Sara Lindström;Joe Dennis;Jonathan Beesley

  1400
  Citations

• Epidemiology of sepsis in Germany: results from a national prospective multicenter study

  Christoph Engel;Frank M. Brunkhorst;Hans-Georg Bone;Reinhard Brunkhorst

  1044
  Citations

• Polygenic Risk Scores for Prediction of Breast Cancer and Breast Cancer Subtypes

  Nasim Mavaddat;Kyriaki Michailidou;Kyriaki Michailidou;Joe Dennis;Michael Lush

  940
  Citations

• Germline mutations in breast and ovarian cancer pedigrees establish RAD51C as a human cancer susceptibility gene

  Alfons Meindl;Heide Hellebrand;Constanze Wiek;Verena Erven

  894
  Citations

• Revised guidelines for the clinical management of Lynch syndrome (HNPCC): recommendations by a group of European experts

  Hans F A Vasen;Ignacio Blanco;Katja Aktan-Collan;Jessica P Gopie

  839
  Citations

• Guidelines for the clinical management of familial adenomatous polyposis (FAP)

  H. F. A Vasen;G. Moslein;A. Alonso;S. Aretz

  811
  Citations

• Breast Cancer Risk Genes - Association Analysis in More than 113,000 Women

  Leila Dorling;Sara Carvalho;Jamie Allen

  783
  Citations

• Guidelines for the clinical management of Lynch syndrome (hereditary non-polyposis cancer)

  Hans F.A. Vasen;Gabriele Möslein;Angel Alonso;Inge Bernstein

  746
  Citations

• Pathology of Breast and Ovarian Cancers among BRCA1 and BRCA2 Mutation Carriers: Results from the Consortium of Investigators of Modifiers of BRCA1/2 (CIMBA).

  Nasim Mavaddat;Daniel Barrowdale;Irene L. Andrulis;Susan M. Domchek

  732
  Citations

• Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer

  Stig E. Bojesen;Stig E. Bojesen;Karen A. Pooley;Sharon E. Johnatty;Jonathan Beesley

  643
  Citations

• Association of type and location of BRCA1 and BRCA2 mutations with risk of breast and ovarian cancer.

  Timothy R. Rebbeck;Nandita Mitra;Fei Wan;Olga M. Sinilnikova

  513
  Citations

• Cancer risks by gene, age, and gender in 6350 carriers of pathogenic mismatch repair variants: findings from the Prospective Lynch Syndrome Database

  Mev Dominguez-Valentin;Julian R. Sampson;Toni T. Seppälä;Sanne W. ten Broeke

  512
  Citations

• Application of a 5-tiered scheme for standardized classification of 2,360 unique mismatch repair gene variants in the InSiGHT locus-specific database

  Bryony A Thompson;Bryony A Thompson;Amanda B Spurdle;John-Paul Plazzer;Marc S Greenblatt

  493
  Citations

• Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer

  Catherine M Phelan;Karoline B Kuchenbaecker;Karoline B Kuchenbaecker;Jonathan P Tyrer;Siddhartha P Kar

  457
  Citations

• Contralateral Breast Cancer Risk in BRCA1 and BRCA2 Mutation Carriers

  Monika K. Graeser;Christoph Engel;Kerstin Rhiem;Dorothea Gadzicki

  416
  Citations

• A locus on 19p13 modifies risk of breast cancer in BRCA1 mutation carriers and is associated with hormone receptor-negative breast cancer in the general population

  Antonis C. Antoniou;Xianshu Wang;Zachary S. Fredericksen;Lesley McGuffog

  404
  Citations

• Expanded Extracolonic Tumor Spectrum in MUTYH-Associated Polyposis

  Stefanie Vogt;Natalie Jones;Daria Christian;Christoph Engel

  389
  Citations

• Genome-wide association study in BRCA1 mutation carriers identifies novel loci associated with breast and ovarian cancer risk

  Fergus J. Couch;Xianshu Wang;Lesley McGuffog;Andrew Lee

  372
  Citations