William J. Pavan

What is he best known for?

The fields of study he is best known for:

• Gene
• DNA
• Genetics

William J. Pavan mostly deals with Genetics, Melanocyte, Cell biology, SOX10 and Neural crest. His works in Gene, Transcription factor, Genome, Transcriptome and Melanoma are all subjects of inquiry into Genetics. In his research on the topic of Melanocyte, Transactivation, PAX3 and Melanoblast is strongly related with Microphthalmia-associated transcription factor.

His work deals with themes such as Neurocristopathy and Genetic variation, which intersect with SOX10. His Neural crest research focuses on subjects like Regulation of gene expression, which are linked to Dopachrome tautomerase, Signal transduction and Genetically modified mouse. His Genomics research is multidisciplinary, incorporating elements of Polyadenylation, Transcription and Transcriptional regulation.

His most cited work include:

• The Transcriptional Landscape of the Mammalian Genome (2876 citations)
• Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs (1378 citations)
• Niemann-Pick C1 Disease Gene: Homology to Mediators of Cholesterol Homeostasis (1205 citations)

What are the main themes of his work throughout his whole career to date?

The scientist’s investigation covers issues in Genetics, Neural crest, SOX10, Molecular biology and Cell biology. His is involved in several facets of Genetics study, as is seen by his studies on Gene, Melanocyte, Regulation of gene expression, Allele and Mutation. In general Neural crest study, his work on Melanoblast often relates to the realm of Endothelin 3, thereby connecting several areas of interest.

He combines subjects such as Enhancer, Cancer research and Microphthalmia-associated transcription factor with his study of SOX10. His research in Molecular biology intersects with topics in Positional cloning, Gene expression, Transgene, Yeast artificial chromosome and Candidate gene. He interconnects Endocrinology, Internal medicine and Cellular differentiation in the investigation of issues within Cell biology.

He most often published in these fields:

• Genetics (45.88%)
• Neural crest (21.18%)
• SOX10 (20.59%)

What were the highlights of his more recent work (between 2013-2021)?

• Genetics (45.88%)
• Disease (8.82%)
• Immunology (11.18%)

In recent papers he was focusing on the following fields of study:

William J. Pavan spends much of his time researching Genetics, Disease, Immunology, Melanoma and Melanocyte. The Genetics study combines topics in areas such as Genome-wide association study and Genetic association. His study on Melanoma also encompasses disciplines like

• Linkage disequilibrium and SNP most often made with reference to Expression quantitative trait loci,
• microRNA together with Cell cycle, Transcriptome and Computational biology.

His Melanocyte study combines topics in areas such as Phenotype and Neural crest. He has included themes like Chromatin, Regulation of gene expression, Transcription factor and Cell biology in his Epigenetics study. His Regulation of gene expression research integrates issues from Microphthalmia-associated transcription factor, Cellular differentiation and SOX10.

Between 2013 and 2021, his most popular works were:

• Loci associated with skin pigmentation identified in African populations (159 citations)
• Glial-cell-derived neuroregulators control type 3 innate lymphoid cells and gut defence (150 citations)
• Intrathecal 2-hydroxypropyl-β-cyclodextrin decreases neurological disease progression in Niemann-Pick disease, type C1: a non-randomised, open-label, phase 1–2 trial (146 citations)

In his most recent research, the most cited papers focused on:

• Gene
• DNA
• Genetics

His main research concerns Melanocyte, Genetics, Genome-wide association study, Gene and Cell biology. His Melanocyte research includes elements of TFAP2A, Zebrafish and Neural crest. His Genome-wide association study research is multidisciplinary, relying on both OCA2, SLC24A5, Genetic association, Dark skin and Human skin.

His Allele and Fixation study are his primary interests in Gene. His research investigates the connection between Cell biology and topics such as Cell type that intersect with issues in Catenin and Signal transduction. His studies in Cancer research integrate themes in fields like Microphthalmia-associated transcription factor and SOX10.