World's Best Scientists 2026 revealed!

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Genetics

D-Index
89
Citations
48028
World Ranking
1096
National Ranking
35

Research.com Recognitions

  • 2016 - Member of the National Academy of Sciences
  • 2012 - Fellow of the American Academy of Arts and Sciences
  • 2005 - Fellow of the American Association for the Advancement of Science (AAAS)
  • 2005 - Fellow of the Royal Society of Canada Academy of Science

Overview

Philip Hieter is affiliated with the University of British Columbia in Canada. Their research spans the field of Biochemistry, Genetics, and Molecular Biology with a focus on several subfields including Molecular Biology, Genetics, Cancer Research, Cell Biology, and Biomedical Engineering.

The main topics covered in Philip Hieter's work include:

  • Genomics and Rare Diseases
  • Genomics and Chromatin Dynamics
  • DNA Repair Mechanisms
  • Genomic Variations and Chromosomal Abnormalities
  • CRISPR and Genetic Engineering
  • RNA Research and Splicing
  • Cancer Genomics and Diagnostics

Frequent collaborators within their work are:

  • Nigel J. O'Neil
  • Paul Pavlidis
  • Sanja Rogić
  • Hugo J. Bellen
  • Akil Hamza

Philip Hieter has published extensively in several venues, with frequent publications appearing in:

  • Genetics (3 publications)
  • G3 Genes Genomes Genetics (2 publications)
  • The American Journal of Human Genetics
  • Life Science Alliance
  • Human Mutation

Recent papers authored by or including Philip Hieter demonstrate interests in genetics, model organisms, and rare disease networks. Selected works include:

  • "The Canadian Rare Diseases Models and Mechanisms (RDMM) Network: Connecting Understudied Genes to Model Organisms," 2020, The American Journal of Human Genetics
  • "Paralogous synthetic lethality underlies genetic dependencies of the cancer-mutated gene STAG2," 2021, Life Science Alliance
  • "Cross-Species Complementation of Nonessential Yeast Genes Establishes Platforms for Testing Inhibitors of Human Proteins," 2020, Genetics
  • "A Robust Toolkit for Functional Profiling of the Yeast Genome," 2021, UNC Libraries
  • "ModelMatcher: A scientist-centric online platform to facilitate collaborations between stakeholders of rare and undiagnosed disease research," 2022, Human Mutation

Philip Hieter has been recognized by multiple professional bodies, including membership and fellowships such as:

  • Member of the National Academy of Sciences (2016)
  • Fellow of the American Academy of Arts and Sciences (2012)
  • Fellow of the American Association for the Advancement of Science (AAAS) (2005)
  • Fellow of the Royal Society of Canada, Academy of Science (2005)

Best Publications

  • A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae.

    Robert S. Sikorski;Philip Hieter

  • Designer deletion strains derived from Saccharomyces cerevisiae S288C: a useful set of strains and plasmids for PCR-mediated gene disruption and other applications.

    Carrie Baker Brachmann;Adrian Davies;Gregory J. Cost;Emerita Caputo

  • Multifunctional yeast high-copy-number shuttle vectors

    Thomas W. Christianson;Robert S. Sikorski;Michael Dante;James H. Shero

  • Characterization of the yeast transcriptome

    Victor E. Velculescu;Bert Vogelstein;Kenneth W. Kinzler

  • A 20s complex containing CDC27 and CDC16 catalyzes the mitosis-specific conjugation of ubiquitin to cyclin B

    Randall W King;Jan-Michael Peters;Stuart Tugendreich;Mark Rolfe

  • Developmental hierarchy of immunoglobulin gene rearrangements in human leukemic pre-B-cells

    S J Korsmeyer;P A Hieter;J V Ravetch;D G Poplack

  • Immunoglobulin gene rearrangement and cell surface antigen expression in acute lymphocytic leukemias of T cell and B cell precursor origins.

    S J Korsmeyer;A Arnold;A Bakhshi;J V Ravetch

  • A repeating amino acid motif in CDC23 defines a family of proteins and a new relationship among genes required for mitosis and RNA synthesis.

    Robert S. Sikorski;Mark S. Boguski;Mark Goebl;Philip Hieter

  • Synthetic lethality and cancer

    Nigel J. O'Neil;Melanie L. Bailey;Philip Hieter

  • Ctf7p is essential for sister chromatid cohesion and links mitotic chromosome structure to the DNA replication machinery

    Robert V. Skibbens;Laura B. Corson;Doug Koshland;Philip Hieter

  • Mitotic stability of yeast chromosomes: A colony color assay that measures nondisjunction and chromosome loss

    Philip Hieter;Carl Mann;Michael Snyder;Ronald W. Davis

  • Functional Genomics: It's All How You Read It

    Philip Hieter;Mark Boguski

  • Chromatid cohesion defects may underlie chromosome instability in human colorectal cancers.

    Thomas D. Barber;Kirk McManus;Karen W Y Yuen;Marcelo Reis

  • Cloned human and mouse kappa immunoglobulin constant and J region genes conserve homology in functional segments.

    Philip A. Hieter;Edward E. Max;J.G. Seidman;Jacob V. Maizel

  • Characterization of the CHD family of proteins.

    Trevor Woodage;Munira A. Basrai;Andreas D. Baxevanis;Philip Hieter

  • TEL1, an S. cerevisiae homolog of the human gene mutated in ataxia telangiectasia, is functionally related to the yeast checkpoint gene MEC1

    Dwight M Morrow;Danilo A Tagle;Yosef Shiloh;Francis S Collins

  • CX-5461 is a DNA G-quadruplex stabilizer with selective lethality in BRCA1/2 deficient tumours.

    Hong Xu;Marco Di Antonio;Steven McKinney;Veena Mathew

  • SGT1 Encodes an Essential Component of the Yeast Kinetochore Assembly Pathway and a Novel Subunit of the SCF Ubiquitin Ligase Complex

    Katsumi Kitagawa;Dorota Skowyra;Stephen J Elledge;J.Wade Harper

  • Identification of RFC(Ctf18p, Ctf8p, Dcc1p): an alternative RFC complex required for sister chromatid cohesion in S. cerevisiae.

    Melanie L. Mayer;Steven P. Gygi;Ruedi Aebersold;Philip Hieter

  • Mitotic chromosome transmission fidelity mutants in Saccharomyces cerevisiae.

    F Spencer;S L Gerring;C Connelly;P Hieter

Frequent Co-Authors

Philip Leder
Philip Leder Harvard University
Mark S. Boguski
Mark S. Boguski National Institutes of Health
Jef D. Boeke
Jef D. Boeke New York University
Thomas A. Waldmann
Thomas A. Waldmann National Institutes of Health
Roger H. Reeves
Roger H. Reeves Johns Hopkins University School of Medicine
William J. Pavan
William J. Pavan National Institutes of Health
Nevan J. Krogan
Nevan J. Krogan University of California, San Francisco
Kym M. Boycott
Kym M. Boycott Children's Hospital of Eastern Ontario
James C. Mullikin
James C. Mullikin National Institutes of Health
Stylianos E. Antonarakis
Stylianos E. Antonarakis University of Geneva

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