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Brenda J. Andrews

Brenda J. Andrews

D-Index & Metrics

Genetics

D-Index
92
Citations
37880
World Ranking
993
National Ranking
28

Molecular Biology

D-Index
92
Citations
37880
World Ranking
693
National Ranking
20

Research.com Recognitions

  • 2020 - Member of the National Academy of Sciences
  • 2010 - Fellow of the American Association for the Advancement of Science (AAAS)
  • 2005 - Fellow of the Royal Society of Canada Academy of Science

Overview

Brenda J. Andrews is affiliated with the University of Toronto in Canada. Their research primarily spans the field of Biochemistry, Genetics and Molecular Biology, with a significant focus on Molecular Biology, Biophysics, Genetics, Oncology, and Cell Biology.

The scientist's work encompasses several main topics, including:

  • Bioinformatics and Genomic Networks
  • Fungal and yeast genetics research
  • Cell Image Analysis Techniques
  • Single-cell and spatial transcriptomics
  • CRISPR and Genetic Engineering
  • Ubiquitin and proteasome pathways
  • RNA Research and Splicing

Brenda J. Andrews has contributed to multiple research articles published in prominent scientific journals. Some recent papers include:

  • Exploring whole-genome duplicate gene retention with complex genetic interaction analysis, 2020, Science
  • Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism, 2020, Nature Metabolism
  • Environmental robustness of the global yeast genetic interaction network, 2021, Science
  • A genome-scale yeast library with inducible expression of individual genes, 2021, Molecular Systems Biology
  • Systematic analysis of bypass suppression of essential genes, 2020, Molecular Systems Biology

Frequent coauthors in their research include:

  • Charles Boone
  • Chad L. Myers
  • Michael Costanzo
  • Matej Ušaj
  • Maximilian Billmann

The scientist's publications are often found in several key venues, notably:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Molecular Systems Biology
  • eLife
  • G3 Genes Genomes Genetics
  • Science

Brenda J. Andrews has been recognized by several professional organizations, including election as a Member of the National Academy of Sciences in 2020, designation as a Fellow of the American Association for the Advancement of Science (AAAS) in 2010, and admission as a Fellow of the Royal Society of Canada in 2005 under the Academy of Science.

Best Publications

  • The genetic landscape of a cell.

    Michael Costanzo;Anastasia Baryshnikova;Jeremy Bellay;Yungil Kim

  • Global Mapping of the Yeast Genetic Interaction Network

    Amy Hin Yan Tong;Guillaume Lesage;Gary D. Bader;Huiming Ding

  • Systematic Genetic Analysis with Ordered Arrays of Yeast Deletion Mutants

    Amy Hin Yan Tong;Marie Evangelista;Ainslie B. Parsons;Hong Xu

  • A global genetic interaction network maps a wiring diagram of cellular function

    Michael Costanzo;Benjamin VanderSluis;Elizabeth N. Koch;Anastasia Baryshnikova

  • Global Analysis of Protein Phosphorylation in Yeast

    Jason Ptacek;Geeta Devgan;Gregory Michaud;Heng Zhu

  • Functional dissection of protein complexes involved in yeast chromosome biology using a genetic interaction map

    Sean R. Collins;Kyle M. Miller;Nancy L. Maas;Assen Roguev

  • Exploration of the Function and Organization of the Yeast Early Secretory Pathway through an Epistatic Miniarray Profile

    Maya Schuldiner;Sean R. Collins;Natalie J. Thompson;Vladimir Denic

  • Mapping Pathways and Phenotypes by Systematic Gene Overexpression

    Richelle Sopko;Dongqing Huang;Nicolle Preston;Gordon Chua

  • Exploring genetic interactions and networks with yeast

    Charles Boone;Howard Bussey;Brenda J. Andrews

  • The Clk/Sty protein kinase phosphorylates SR splicing factors and regulates their intranuclear distribution.

    Karen Colwill;Tony Pawson;Brenda Andrews;Jayendra Prasad

  • Exploration of essential gene functions via titratable promoter alleles

    Sanie Mnaimneh;Armaity P Davierwala;Jennifer Haynes;Jason Moffat

  • Exploring the mode-of-action of bioactive compounds by chemical-genetic profiling in yeast.

    Ainslie B. Parsons;Andres Lopez;Inmar E. Givoni;David E. Williams

  • CDK Activity Antagonizes Whi5, an Inhibitor of G1/S Transcription in Yeast

    Michael Costanzo;Joy L Nishikawa;Joy L Nishikawa;Xiaojing Tang;Jonathan S Millman

  • Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing

    Xinping Yang;Xinping Yang;Jasmin Coulombe-Huntington;Shuli Kang;Gloria M. Sheynkman

  • Evaluation and Design of Genome-Wide CRISPR/SpCas9 Knockout Screens.

    Traver Hart;Amy Hin Yan Tong;Katie Chan;Jolanda Van Leeuwen

  • Systematic exploration of essential yeast gene function with temperature-sensitive mutants

    Zhijian Li;Franco J. Vizeacoumar;Sondra Bahr;Jingjing Li

  • Deciphering protein kinase specificity through large-scale analysis of yeast phosphorylation site motifs

    Janine Mok;Philip M. Kim;Philip M. Kim;Hugo Y.K. Lam;Stacy Piccirillo

  • Quantitative analysis of fitness and genetic interactions in yeast on a genome scale

    Anastasia Baryshnikova;Michael Costanzo;Yungil Kim;Huiming Ding

  • Comprehensive curation and analysis of global interaction networks in Saccharomyces cerevisiae

    Teresa Reguly;Ashton Breitkreutz;Lorrie Boucher;Bobby Joe Breitkreutz

  • Global Mapping of the Yeast Genetic Interaction Network: Discovering Gene and Drug Function

    Amy Tong;Guillaume Lesage;Ainslie Parsons;Brenda Andrews

Frequent Co-Authors

Charles Boone
Charles Boone University of Toronto
Michael Costanzo
Michael Costanzo University of Toronto
Chad L. Myers
Chad L. Myers University of Minnesota
Jason Moffat
Jason Moffat University of Toronto
Frederick P. Roth
Frederick P. Roth Lunenfeld-Tanenbaum Research Institute
Anne-Claude Gingras
Anne-Claude Gingras Lunenfeld-Tanenbaum Research Institute
Corey Nislow
Corey Nislow University of British Columbia
Mike Tyers
Mike Tyers University of Montreal
Gary D. Bader
Gary D. Bader University of Toronto
Grant W. Brown
Grant W. Brown University of Toronto

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