World's Best Scientists 2026 revealed!

D-Index & Metrics

Genetics

D-Index
82
Citations
45016
World Ranking
1447
National Ranking
49

Overview

Frederick P. Roth is affiliated with the Lunenfeld-Tanenbaum Research Institute in Canada. Their research primarily spans the field of Biochemistry, Genetics and Molecular Biology, with a total of 172 publications. Within this broad area, their work is concentrated on several subfields including Molecular Biology, Genetics, Infectious Diseases, Cancer Research, and Cell Biology.

The main topics covered by their research include:

  • Genomics and Rare Diseases
  • CRISPR and Genetic Engineering
  • Genomics and Phylogenetic Studies
  • SARS-CoV-2 and COVID-19 Research
  • Cancer Genomics and Diagnostics
  • Bioinformatics and Genomic Networks
  • Genetic Associations and Epidemiology

Frederick P. Roth has published extensively, with some recent papers illustrating the variety and scope of their work. Notable papers include:

  • A reference map of the human binary protein interactome (2020, Nature)
  • Systems analysis of RhoGEF and RhoGAP regulatory proteins reveals spatially organized RAC1 signalling from integrin adhesions (2020, Nature Cell Biology)
  • Improved pathogenicity prediction for rare human missense variants (2021, The American Journal of Human Genetics)
  • A SARS-CoV-2 - host proximity interactome (2020, bioRxiv (Cold Spring Harbor Laboratory))
  • An Atlas of Variant Effects to understand the genome at nucleotide resolution (2023, Genome biology)

The scientist frequently publishes in venues such as bioRxiv (Cold Spring Harbor Laboratory), Genome biology, Preprints.org, The American Journal of Human Genetics, and Bioinformatics.

Frederick P. Roth has collaborated often with a group of frequent co-authors, including:

  • Jochen Weile
  • Atina G. Coté
  • Roujia Li
  • Dae-Kyum Kim
  • Nishka Kishore

Best Publications

  • Towards a proteome-scale map of the human protein–protein interaction network

    Jean François Rual;Kavitha Venkatesan;Tong Hao;Tomoko Hirozane-Kishikawa

  • The genetic landscape of a cell.

    Michael Costanzo;Anastasia Baryshnikova;Jeremy Bellay;Yungil Kim

  • Global Mapping of the Yeast Genetic Interaction Network

    Amy Hin Yan Tong;Guillaume Lesage;Gary D. Bader;Huiming Ding

  • A Map of the Interactome Network of the Metazoan C. elegans

    Siming Li;Christopher M. Armstrong;Nicolas Bertin;Hui Ge

  • Evidence for dynamically organized modularity in the yeast protein–protein interaction network

    Jing-Dong J. Han;Nicolas Bertin;Tong Hao;Debra S. Goldberg

  • High-Quality Binary Protein Interaction Map of the Yeast Interactome Network

    Haiyuan Yu;Pascal Braun;Muhammed A Yildirim;Irma Lemmens

  • High-Resolution CRISPR Screens Reveal Fitness Genes and Genotype-Specific Cancer Liabilities

    Traver Hart;Megha Chandrashekhar;Michael Aregger;Zachary Steinhart

  • A proteome-scale map of the human interactome network

    Thomas Rolland;Murat Taşan;Benoit Charloteaux;Samuel J. Pevzner

  • Finding DNA regulatory motifs within unaligned noncoding sequences clustered by whole-genome mRNA quantitation

    Frederick P. Roth;Jason D. Hughes;Preston W. Estep;George M. Church

  • An empirical framework for binary interactome mapping

    Kavitha Venkatesan;Kavitha Venkatesan;Jean François Rual;Alexei Vazquez;Alexei Vazquez;Ulrich Stelzl

  • A reference map of the human binary protein interactome

    Katja Luck;Dae Kyum Kim;Luke Lambourne;Kerstin Spirohn

  • Evidence for Network Evolution in an Arabidopsis Interactome Map

    Matija Dreze;Anne-Ruxandra Carvunis;Benoit Charloteaux

  • Independently evolved virulence effectors converge onto hubs in a plant immune system network

    M. Shahid Mukhtar;Anne-Ruxandra Carvunis;Anne-Ruxandra Carvunis;Matija Dreze;Matija Dreze;Petra Epple

  • A Highly Conserved Program of Neuronal Microexons Is Misregulated in Autistic Brains

    Manuel Irimia;Manuel Irimia;Robert J. Weatheritt;Jonathan D. Ellis;Neelroop N. Parikshak

  • Characterizing gene sets with FuncAssociate.

    Gabriel F. Berriz;Oliver D. King;Barbara Bryant;Chris Sander

  • Widespread Macromolecular Interaction Perturbations in Human Genetic Disorders

    Nidhi Sahni;Song Yi;Mikko Taipale;Juan I. Fuxman Bass

  • Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing

    Xinping Yang;Xinping Yang;Jasmin Coulombe-Huntington;Shuli Kang;Gloria M. Sheynkman

  • Defining genetic interaction

    Ramamurthy Mani;Robert P. St.Onge;John L. Hartman;Guri Giaever

  • Assessing experimentally derived interactions in a small world

    Debra S. Goldberg;Frederick P. Roth

  • An experimentally derived confidence score for binary protein-protein interactions

    Pascal Braun;Murat Tasan;Matija Dreze;Matija Dreze;Miriam Barrios-Rodiles

Frequent Co-Authors

Marc Vidal
Marc Vidal Harvard University
David E. Hill
David E. Hill Harvard University
Albert-László Barabási
Albert-László Barabási Northeastern University
Yves Jacob
Yves Jacob Institut Pasteur
Anne-Claude Gingras
Anne-Claude Gingras Lunenfeld-Tanenbaum Research Institute
Jan Tavernier
Jan Tavernier Ghent University
Patrick Aloy
Patrick Aloy Institució Catalana de Recerca i Estudis Avançats
Oliver D. King
Oliver D. King University of Massachusetts Chan Medical School
Charles Boone
Charles Boone University of Toronto
Brenda J. Andrews
Brenda J. Andrews University of Toronto

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

For students interested in Genetics, many online programs in healthcare and science offer flexible routes to rewarding careers. Nursing is a popular choice, and some of the best rn to bsn no clinical hours programs allow registered nurses to earn their Bachelor of Science in Nursing fully online—eliminating the need for traditional clinical placements.

Advanced study is also possible with options like the fastest dnp program. These programs let you earn a Doctor of Nursing Practice in a streamlined format, ideal for those looking to quickly advance their expertise in clinical leadership or research. If you’re seeking a more affordable doctoral option, consider the cheapest dnp programs online to keep educational costs in check while boosting your credentials.

For those eager to start their journey in healthcare, medical assistant training can be completed in as little as six weeks. This offers a fast track into clinical work while building a foundation for later genetics or advanced health studies.

Best Scientists Citing Frederick P. Roth

Trending Scientists

Recently Published Articles