Feixiong Cheng mainly investigates Drug repositioning, Drug discovery, Computational biology, Drug and Artificial intelligence. His Drug repositioning research is multidisciplinary, relying on both Proportional hazards model, Network medicine, Inference and Confidence interval. His work carried out in the field of Drug discovery brings together such families of science as Quantitative structure–activity relationship, Kinase and Apoptosis.
His studies examine the connections between Computational biology and genetics, as well as such issues in Human interactome, with regards to Carcinogenesis. The concepts of his Drug study are interwoven with issues in Metabolic heterogeneity, Gene knockdown and SNAI1. His work in Artificial intelligence addresses issues such as Machine learning, which are connected to fields such as Biological network and Repurposing.
His primary areas of investigation include Computational biology, Drug discovery, Drug repositioning, Cancer research and Cancer. His research integrates issues of Genomics, Systems pharmacology, Drug and Interactome in his study of Computational biology. His primary area of study in Interactome is in the field of Human interactome.
His Drug discovery study deals with In silico intersecting with Support vector machine and Data mining. His studies deal with areas such as Bioinformatics, Deep learning, Inference, Artificial intelligence and Network medicine as well as Drug repositioning. His studies in Cancer integrate themes in fields like Exome sequencing, Gene and Gene regulatory network.
Feixiong Cheng mostly deals with Computational biology, Network medicine, Drug repositioning, Interactome and Disease. His Computational biology research is multidisciplinary, incorporating perspectives in Exome sequencing, Genomics, Small molecule, Human interactome and Drug discovery. His work focuses on many connections between Drug discovery and other disciplines, such as Systems pharmacology, that overlap with his field of interest in Systems biology and Biological network.
His study on Drug repositioning is covered under Drug. His study in the field of Antiviral drug is also linked to topics like Coronavirus. His work deals with themes such as Chemokine and Pathogenesis, which intersect with Interactome.
His main research concerns Drug repositioning, Network medicine, Artificial intelligence, Interactome and Drug discovery. His Drug repositioning research is included under the broader classification of Drug. Feixiong Cheng interconnects Inflammatory bowel disease, Observational study, Propensity score matching and Oncology in the investigation of issues within Network medicine.
His Artificial intelligence research incorporates elements of Machine learning, Biological network, MEDLINE and Big data. His study looks at the intersection of Interactome and topics like Systems pharmacology with Repurposing, Antiviral drug and Human interactome. He has included themes like Drug target and Feature vector in his Drug discovery study.
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Network-based drug repurposing for novel coronavirus 2019-nCoV/SARS-CoV-2
Yadi Zhou;Yuan Hou;Jiayu Shen;Yin Huang.
Cell discovery (2020)
Prediction of Drug-Target Interactions and Drug Repositioning via Network-Based Inference
Feixiong Cheng;Chuang Liu;Jing Jiang;Weiqiang Lu.
PLOS Computational Biology (2012)
Network-based prediction of drug combinations.
Feixiong Cheng;István A. Kovács;István A. Kovács;Albert László Barabási.
Nature Communications (2019)
Network-based approach to prediction and population-based validation of in silico drug repurposing
Feixiong Cheng;Feixiong Cheng;Rishi J. Desai;Diane E. Handy;Ruisheng Wang.
Nature Communications (2018)
SoNar, a Highly Responsive NAD+/NADH Sensor, Allows High-Throughput Metabolic Screening of Anti-tumor Agents
Yuzheng Zhao;Qingxun Hu;Feixiong Cheng;Ni Su.
Cell Metabolism (2015)
Estimation of ADME properties with substructure pattern recognition.
Jie Shen;Feixiong Cheng;You Xu;Weihua Li.
Journal of Chemical Information and Modeling (2010)
deepDR: a network-based deep learning approach to in silico drug repositioning.
Xiangxiang Zeng;Siyi Zhu;Xiangrong Liu;Yadi Zhou.
Bioinformatics (2019)
Pan-cancer Alterations of the MYC Oncogene and Its Proximal Network across the Cancer Genome Atlas
Franz X. Schaub;Varsha Dhankani;Ashton C. Berger;Mihir Trivedi.
Cell systems (2018)
Machine learning-based prediction of drug-drug interactions by integrating drug phenotypic, therapeutic, chemical, and genomic properties.
Feixiong Cheng;Zhongming Zhao.
Journal of the American Medical Informatics Association (2014)
Genomic, Pathway Network, and Immunologic Features Distinguishing Squamous Carcinomas
Joshua D. Campbell;Joshua D. Campbell;Joshua D. Campbell;Christina Yau;Christina Yau;Reanne Bowlby;Yuexin Liu.
Cell Reports (2018)
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