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Neuroscience

D-Index
51
Citations
10430
World Ranking
5504
National Ranking
2448

Overview

Andrew A. Pieper is affiliated with the University of Iowa in the United States and has contributed extensively to fields intersecting medicine, biochemistry, genetics, and molecular biology. Their research spans a wide range of topics, predominantly focusing on neurological disorders and molecular mechanisms related to brain health and disease.

The scientist's primary fields of study include Medicine and Biochemistry, Genetics and Molecular Biology, with subfields prominently featuring Molecular Biology, Neurology, Physiology, Genetics, and Epidemiology.

Key research topics explored by Andrew A. Pieper encompass:

  • Alzheimer's disease research and treatments
  • Bioinformatics and Genomic Networks
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Traumatic Brain Injury and Neurovascular Disturbances
  • Computational Drug Discovery Methods
  • Tryptophan and brain disorders
  • Traumatic Brain Injury Research

Some of the recent papers published by Andrew A. Pieper include:

  • "Reducing acetylated tau is neuroprotective in brain injury", 2021, Cell
  • "Endophenotype-based in silico network medicine discovery combined with insurance record data mining identifies sildenafil as a candidate drug for Alzheimer's disease", 2021, Nature Aging
  • "Oligodendroglial glycolytic stress triggers inflammasome activation and neuropathology in Alzheimer's disease", 2020, Science Advances
  • "Network medicine links SARS-CoV-2/COVID-19 infection to brain microvascular injury and neuroinflammation in dementia-like cognitive impairment", 2021, Alzheimer s Research & Therapy
  • "X-linked ubiquitin-specific peptidase 11 increases tauopathy vulnerability in women", 2022, Cell

Andrew A. Pieper has frequently collaborated with several coauthors, including:

  • Feixiong Cheng
  • Jeffrey L. Cummings
  • Yadi Zhou
  • James B. Leverenz
  • Edwin Vázquez-Rosa

Their publications have appeared predominantly in venues such as:

  • Alzheimer s & Dementia
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Neurotherapeutics
  • Proceedings of the National Academy of Sciences
  • Alzheimer s Research & Therapy

Best Publications

  • Poly(ADP-ribose) polymerase gene disruption renders mice resistant to cerebral ischemia

    Mikael J.L. Eliasson;Kenji Sampei;Allen S. Mandir;Patricia D. Hurn

  • Poly (ADP-ribose) polymerase, nitric oxide and cell death.

    Andrew A. Pieper;Ajay Verma;Jie Zhang;Solomon H. Snyder

  • Discovery of a Proneurogenic, Neuroprotective Chemical

    Andrew A. Pieper;Shanhai Xie;Emanuela Capota;Sandi Jo Estill

  • Poly(ADP-ribose) polymerase-deficient mice are protected from streptozotocin-induced diabetes

    Andrew A. Pieper;Daniel J. Brat;Daniel J. Brat;David K. Krug;Crystal C. Watkins

  • FGF21 Mediates Endocrine Control of Simple Sugar Intake and Sweet Taste Preference by the Liver

    Stephanie von Holstein-Rathlou;Lucas D. BonDurant;Lila Peltekian;Meghan C. Naber

  • P7C3 Neuroprotective Chemicals Function by Activating the Rate-limiting Enzyme in NAD Salvage

    Gelin Wang;Ting Han;Deepak Nijhawan;Pano Theodoropoulos

  • A suppressor screen in Mecp2 mutant mice implicates cholesterol metabolism in Rett syndrome

    Christie M Buchovecky;Stephen D Turley;Hannah M Brown;Hannah M Brown;Stephanie M Kyle

  • Development of Proneurogenic, Neuroprotective Small Molecules

    Karen S. MacMillan;Jacinth Naidoo;Jue Liang;Lisa Melito

  • The neuronal PAS domain protein 3 transcription factor controls FGF-mediated adult hippocampal neurogenesis in mice.

    Andrew A. Pieper;Xinle Wu;Tina W. Han;Sandi Jo Estill

  • Myocardial postischemic injury is reduced by polyADPripose polymerase-1 gene disruption.

    Andrew A. Pieper;Thorsten Walles;Guo Wei;Emily E. Clements

  • Reducing acetylated tau is neuroprotective in brain injury.

    Min Kyoo Shin;Min Kyoo Shin;Edwin Vázquez-Rosa;Edwin Vázquez-Rosa;Yeojung Koh;Yeojung Koh;Matasha Dhar;Matasha Dhar

  • Post-treatment with an inhibitor of poly(ADP-ribose) polymerase attenuates cerebral damage in focal ischemia.

    Kazushi Takahashi;Andrew A. Pieper;Sidney E. Croul;Jie Zhang

  • The P7C3 class of neuroprotective compounds exerts antidepressant efficacy in mice by increasing hippocampal neurogenesis

    Walker Ak;Rivera Pd;Wang Q;Chuang Jc

  • Unesterified Cholesterol Accumulation in Late Endosomes/Lysosomes Causes Neurodegeneration and Is Prevented by Driving Cholesterol Export from This Compartment

    Amal Aqul;Benny Liu;Charina M. Ramirez;Andrew A. Pieper

  • Oligodendroglial glycolytic stress triggers inflammasome activation and neuropathology in Alzheimer’s disease

    Xinwen Zhang;Rihua Wang;Di Hu;Xiaoyan Sun

  • Neuroprotective efficacy of aminopropyl carbazoles in a mouse model of amyotrophic lateral sclerosis

    Rachel Tesla;Hamilton Parker Wolf;Pin Xu;Jordan Drawbridge

  • Neuroprotective efficacy of aminopropyl carbazoles in a mouse model of Parkinson disease

    Héctor De Jesús-Cortés;Pin Xu;Jordan Drawbridge;Sandi Jo Estill

  • Wild-type microglia do not reverse pathology in mouse models of Rett syndrome

    Jieqi Wang;Jan Eike Wegener;Teng Wei Huang;Smitha Sripathy

  • Network medicine links SARS-CoV-2/COVID-19 infection to brain microvascular injury and neuroinflammation in dementia-like cognitive impairment.

    Yadi Zhou;Jielin Xu;Yuan Hou;James B. Leverenz;James B. Leverenz

  • Poly(ADP‐Ribose) Synthetase Activation: An Early Indicator of Neurotoxic DNA Damage

    Jie Zhang;Andrew Pieper;Solomon H. Snyder

  • Poly(ADP-ribosyl)ation basally activated by DNA strand breaks reflects glutamate–nitric oxide neurotransmission

    Andrew A. Pieper;Seth Blackshaw;Emily E. Clements;Daniel J. Brat

Frequent Co-Authors

Solomon H. Snyder
Solomon H. Snyder Johns Hopkins University School of Medicine
Jeffrey L. Cummings
Jeffrey L. Cummings University of Nevada, Las Vegas
James B. Leverenz
James B. Leverenz Cleveland Clinic
Lara Jehi
Lara Jehi Cleveland Clinic
W. Dalton Dietrich
W. Dalton Dietrich University of Miami
John A. Wemmie
John A. Wemmie University of Iowa
Valina L. Dawson
Valina L. Dawson Johns Hopkins University School of Medicine
Amy S. Lee
Amy S. Lee University of Southern California
Haiyuan Yu
Haiyuan Yu Cornell University
Val C. Sheffield
Val C. Sheffield University of Iowa

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