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Medicine

D-Index
112
Citations
43970
World Ranking
5159
National Ranking
509

Overview

Christoph Thiemermann is affiliated with Queen Mary University of London in the United Kingdom. Their research spans primarily across the fields of Medicine and Immunology and Microbiology, with a substantial focus on immunology as a subfield.

The scientist's work encompasses several specialized subfields including Immunology, Molecular Biology, Epidemiology, Critical Care and Intensive Care Medicine, and Surgery. Their research addresses key topics such as Sepsis Diagnosis and Treatment, Immune Response and Inflammation, Adipokines, Inflammation, and Metabolic Diseases, Trauma, Hemostasis, Coagulopathy, Resuscitation, Immune cells in cancer, Intensive Care Unit Cognitive Disorders, and Cytokine Signaling Pathways and Interactions.

Among the recent papers associated with their research are:

  • Role of Metabolic Endotoxemia in Systemic Inflammation and Potential Interventions (2021, Frontiers in Immunology)
  • Development and validation of a reinforcement learning algorithm to dynamically optimize mechanical ventilation in critical care (2021, npj Digital Medicine)
  • Inhibition of Bruton's TK regulates macrophage NF-κB and NLRP3 inflammasome activation in metabolic inflammation (2020, British Journal of Pharmacology)
  • Ribonuclease 1 attenuates septic cardiomyopathy and cardiac apoptosis in a murine model of polymicrobial sepsis (2020, JCI Insight)
  • Senescence and the Aging Immune System as Major Drivers of Chronic Kidney Disease (2020, Frontiers in Cell and Developmental Biology)

Frequent co-authors in their scientific collaborations include Massimo Collino, Debora Collotta, Gustavo Ferreira Alves, Lukas Märtin, and Sina M. Coldewey. This network highlights a collaborative approach to tackling complex biomedical questions.

The most common publication venues for their studies are Frontiers in Immunology, bioRxiv (Cold Spring Harbor Laboratory), Shock, British Journal of Pharmacology, and Frontiers in Cell and Developmental Biology. Frontiers in Immunology is notably a frequent platform for their disseminated research.

Best Publications

  • Selectivity of nonsteroidal antiinflammatory drugs as inhibitors of constitutive and inducible cyclooxygenase

    Jane A. Mitchell;Pravit Akarasereenont;Christoph Thiemermann;Roderick J. Flower

  • Inhibition of nitric oxide synthesis reduces the hypotension induced by bacterial lipopolysaccharides in the rat in vivo.

    Christoph Thiemermann;John Vane

  • Ligands of the peroxisome proliferator-activated receptors (PPAR-gamma and PPAR-alpha) reduce myocardial infarct size.

    Nicole S Wayman;Yoshiyuki Hattori;Michelle C McDonald;Helder Mota-Filipe

  • Beneficial effects and improved survival in rodent models of septic shock with S-methylisothiourea sulfate, a potent and selective inhibitor of inducible nitric oxide synthase

    Csaba Szabo;Garry J. Southan;Christoph Thiemermann

  • Erythropoietin Protects the Kidney against the Injury and Dysfunction Caused by Ischemia-Reperfusion

    Edward J Sharples;Nimesh Patel;Paul Brown;Keith Stewart

  • Nitric oxide-mediated hyporeactivity to noradrenaline precedes the induction of nitric oxide synthase in endotoxin shock.

    Csaba Szabó;Jane A. Mitchell;Christoph Thiemermann;John R. Vane

  • Vascular hyporeactivity to vasoconstrictor agents and hemodynamic decompensation in hemorrhagic shock is mediated by nitric oxide

    Christoph Thiemermann;Csaba Szabo;Jane A. Mitchell;John R. Vane

  • Definition and drivers of acute traumatic coagulopathy: clinical and experimental investigations

    D. Frith;J. C. Goslings;C. Gaarder;M. Maegele

  • The cell wall components peptidoglycan and lipoteichoic acid from Staphylococcus aureus act in synergy to cause shock and multiple organ failure

    S. J. De Kimpe;Muralitharan Kengatharan;C. Thiemermann;J. R. Vane

  • Tempol, a membrane-permeable radical scavenger, reduces oxidant stress-mediated renal dysfunction and injury in the rat

    Prabal K. Chatterjee;Salvatore Cuzzocrea;Paul A.J. Brown;Kai Zacharowski

  • Inhibition of the activity of poly(ADP ribose) synthetase reduces ischemia-reperfusion injury in the heart and skeletal muscle

    Christoph Thiemermann;Joanne Bowes;Fiona P. Myint;John R. Vane

  • Nitric Oxide and Septic Shock

    Christoph Thiemermann

  • Nonerythropoietic, tissue-protective peptides derived from the tertiary structure of erythropoietin

    Michael Brines;Nimesh S.A. Patel;Pia Villa;Courtenay Brines

  • Mechanism of Gram-positive Shock: Identification of Peptidoglycan and Lipoteichoic Acid Moieties Essential in the Induction of Nitric Oxide Synthase, Shock, and Multiple Organ Failure

    Ken M. Kengatharan;Sjef De Kimpe;Caroline Robson;Simon J. Foster

  • Rosiglitazone, a ligand of the peroxisome proliferator-activated receptor-γ, reduces acute inflammation

    Salvatore Cuzzocrea;Barbara Pisano;Laura Dugo;Angela Ianaro

  • Isothioureas: potent inhibitors of nitric oxide synthases with variable isoform selectivity

    Garry J. Southan;Csaba Szabó;Christoph Thiemermann

  • Inhibition of inducible nitric oxide synthase reduces renal ischemia/reperfusion injury.

    Prabal K. Chatterjee;Nimesh S.A. Patel;Espen O. Kvale;Salvatore Cuzzocrea

  • On the selectivity of superoxide dismutase mimetics and its importance in pharmacological studies

    Carolina Muscoli;Salvatore Cuzzocrea;Dennis P. Riley;Jay L. Zweier

  • ANTI-APOPTOTIC AND ANTI-INFLAMMATORY EFFECTS OF HYDROGEN SULFIDE IN A RAT MODEL OF REGIONAL MYOCARDIAL I/R

    Ahila Sivarajah;Massimo Collino;Mohammed Yasin;Elisa Benetti

  • Vascular hyporeactivity to vasoconstrictor agents and hemodynamic decompensation in hemorrhagic shock is mediated by nitric oxide (NG-nitro-L-arginine methyl ester/dexamethasone/hemorrhagic hypotension/hypovolaemic hypotension/lipopolysaccharide)

    Christoph Thiemermann;Csaba Szab;Jane A. Mitchell;John R. Vane

Frequent Co-Authors

Salvatore Cuzzocrea
Salvatore Cuzzocrea University of Messina
Emanuela Mazzon
Emanuela Mazzon University of Messina
John R. Vane
John R. Vane St Bartholomew's Hospital
Achille P. Caputi
Achille P. Caputi University of Messina
Simon J. Foster
Simon J. Foster University of Sheffield
Csaba Szabó
Csaba Szabó University of Fribourg
Tiziana Genovese
Tiziana Genovese University of Messina
Jane A. Mitchell
Jane A. Mitchell National Institutes of Health
Mauro Perretti
Mauro Perretti Queen Mary University of London
Emanuela Esposito
Emanuela Esposito University of Messina

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