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Immunology

D-Index
79
Citations
37035
World Ranking
1658
National Ranking
820

Overview

Lawrence Fong is affiliated with the University of California, San Francisco in the United States. Their research primarily spans the fields of Medicine and Immunology and Microbiology, with a significant focus on Oncology and Immunology among the subfields of study.

Their scholarly output covers a range of topics related to cancer and immunotherapy. Major themes in their work include:

  • Cancer Immunotherapy and Biomarkers
  • Prostate Cancer Treatment and Research
  • Immunotherapy and Immune Responses
  • CAR-T cell therapy research
  • Radiopharmaceutical Chemistry and Applications
  • Bladder and Urothelial Cancer Treatments
  • Immune Cell Function and Interaction

Several frequent co-authors have collaborated extensively with Fong, including:

  • Li Zhang
  • Rahul Aggarwal
  • Terence W. Friedlander
  • Eric J. Small
  • David Y. Oh

Their work has been published in multiple peer-reviewed venues, with notable frequency in:

  • Journal of Clinical Oncology
  • Regular and Young Investigator Award Abstracts
  • Cancer Research
  • Journal for ImmunoTherapy of Cancer
  • Cancer Immunology Research

Representative recent publications include:

  • "Intratumoral CD4+ T Cells Mediate Anti-tumor Cytotoxicity in Human Bladder Cancer," 2020, Cell
  • "Single-cell RNA-seq reveals cell type-specific molecular and genetic associations to lupus," 2022, Science
  • "Tissue Determinants of Human NK Cell Development, Function, and Residence," 2020, Cell
  • "Cytotoxic CD4+ T cells in cancer: Expanding the immune effector toolbox," 2021, Immunity
  • "Dynamic CD8+ T cell responses to cancer immunotherapy in human regional lymph nodes are disrupted in metastatic lymph nodes," 2023, Cell

Best Publications

  • TGFβ attenuates tumour response to PD-L1 blockade by contributing to exclusion of T cells.

    Sanjeev Mariathasan;Shannon J. Turley;Dorothee Nickles;Alessandra Castiglioni

  • Characterization of circulating T cells specific for tumor-associated antigens in melanoma patients.

    Peter P. Lee;Cassian Yee;Peter A. Savage;Lawrence Fong

  • Suppression of Exosomal PD-L1 Induces Systemic Anti-tumor Immunity and Memory

    Mauro Poggio;Tianyi Hu;Chien Chun Pai;Brandon Chu

  • Altered peptide ligand vaccination with Flt3 ligand expanded dendritic cells for tumor immunotherapy

    Lawrence Fong;Yafei Hou;Alberto Rivas;Claudia Benike

  • Dendritic Cells in Cancer Immunotherapy

    Lawrence Fong;Edgar G. Engleman

  • Systemic Immunity Is Required for Effective Cancer Immunotherapy

    Matthew H. Spitzer;Yaron Carmi;Yaron Carmi;Nathan E. Reticker-Flynn;Serena S. Kwek

  • Intratumoral CD4+ T Cells Mediate Anti-tumor Cytotoxicity in Human Bladder Cancer.

    David Y. Oh;Serena S. Kwek;Siddharth S. Raju;Tony Li

  • Single-cell RNA-seq reveals cell type–specific molecular and genetic associations to lupus

    Unknown

  • Dendritic Cells Injected Via Different Routes Induce Immunity in Cancer Patients

    Lawrence Fong;Dirk Brockstedt;Claudia Benike;Lijun Wu

  • A Pilot Trial of CTLA-4 Blockade with Human Anti-CTLA-4 in Patients with Hormone-Refractory Prostate Cancer

    Eric J. Small;N. Simon Tchekmedyian;Brian I. Rini;Lawrence Fong

  • Improved survival with T cell clonotype stability after anti-CTLA-4 treatment in cancer patients.

    Edward Cha;Mark Klinger;Yafei Hou;Craig Cummings

  • Cytotoxic CD4+ T cells in cancer: Expanding the immune effector toolbox

    Unknown

  • Tissue Determinants of Human NK Cell Development, Function, and Residence

    Pranay Dogra;Chiara Rancan;Wenji Ma;Marta Toth

  • Anti–Cytotoxic T-Lymphocyte Antigen-4 Antibody: The First in an Emerging Class of Immunomodulatory Antibodies for Cancer Treatment

    Lawrence Fong;Eric J. Small

  • Dendritic Cell-Based Xenoantigen Vaccination for Prostate Cancer Immunotherapy

    Lawrence Fong;Dirk Brockstedt;Claudia Benike;Jami K. Breen

  • Dynamic CD8+ T cell responses to cancer immunotherapy in human regional lymph nodes are disrupted in metastatic lymph nodes

    Unknown

  • Phase II Study of the Anti-Cytotoxic T-Lymphocyte–Associated Antigen 4 Monoclonal Antibody, Tremelimumab, in Patients With Refractory Metastatic Colorectal Cancer

    Ki Y. Chung;Ira Gore;Lawrence Fong;Alan Venook

  • A phase I trial of intravenous CG7870, a replication-selective, prostate-specific antigen-targeted oncolytic adenovirus, for the treatment of hormone-refractory, metastatic prostate cancer.

    Eric J. Small;Michael A. Carducci;James M. Burke;Ron Rodriguez

  • Spontaneous autoimmunity prevented by thymic expression of a single self-antigen

    Jason DeVoss;Yafei Hou;Kellsey Johannes;Wen Lu

  • CTLA4 blockade expands FoxP3+ regulatory and activated effector CD4+ T cells in a dose-dependent fashion

    Brian Kavanagh;Shaun O'Brien;David Lee;Yafei Hou

  • Immunomodulatory Activity of Nivolumab in Metastatic Renal Cell Carcinoma.

    Toni K. Choueiri;Mayer Fishman;Bernard Escudier;David F. McDermott

  • Potentiating Endogenous Antitumor Immunity to Prostate Cancer through Combination Immunotherapy with CTLA4 Blockade and GM-CSF

    Lawrence Fong;Serena S. Kwek;Shaun O'Brien;Brian Kavanagh

  • Introduction of soluble proteins into the MHC class I pathway by conjugation to an HIV tat peptide.

    D T Kim;D J Mitchell;D G Brockstedt;L Fong

Frequent Co-Authors

Eric J. Small
Eric J. Small University of California, San Francisco
Toni K. Choueiri
Toni K. Choueiri Harvard University
David I. Quinn
David I. Quinn University of Southern California
Joaquim Bellmunt
Joaquim Bellmunt Beth Israel Deaconess Medical Center
Cora N. Sternberg
Cora N. Sternberg Cornell University
Brian I. Rini
Brian I. Rini Vanderbilt University Medical Center
Dean F. Bajorin
Dean F. Bajorin Memorial Sloan Kettering Cancer Center
David F. McDermott
David F. McDermott Beth Israel Deaconess Medical Center
Bernard Escudier
Bernard Escudier Institut Gustave Roussy
Winald R. Gerritsen
Winald R. Gerritsen Radboud University

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