D-Index & Metrics Best Publications
Immunology
USA
2023

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Immunology D-index 131 Citations 58,347 780 World Ranking 129 National Ranking 86
Medicine D-index 131 Citations 59,333 811 World Ranking 1362 National Ranking 809

Research.com Recognitions

Awards & Achievements

2023 - Research.com Immunology in United States Leader Award

Overview

What is he best known for?

The fields of study he is best known for:

  • Cancer
  • Gene
  • Immune system

Jeffrey Schlom focuses on Immunology, Antigen, Monoclonal antibody, Antibody and Molecular biology. His Immunology study combines topics in areas such as Cancer, Prostate cancer and Cancer research. Jeffrey Schlom has researched Antigen in several fields, including Carcinoembryonic antigen, T cell, Adjuvant, Vaccination and Tumor antigen.

His biological study spans a wide range of topics, including Radioimmunoassay, Transplantation and Pathology. He focuses mostly in the field of Antibody, narrowing it down to topics relating to In vivo and, in certain cases, Radiolabeled CC49. His research in Molecular biology intersects with topics in In vitro, Biodistribution, Recombinant DNA, Epitope and Antigen presentation.

His most cited work include:

  • Radiation modulates the peptide repertoire, enhances MHC class I expression, and induces successful antitumor immunotherapy (981 citations)
  • Grafting of “Abbreviated” Complementarity-Determining Regions Containing Specificity-Determining Residues Essential for Ligand Contact to Engineer a Less Immunogenic Humanized Monoclonal Antibody (912 citations)
  • Overall Survival Analysis of a Phase II Randomized Controlled Trial of a Poxviral-Based PSA-Targeted Immunotherapy in Metastatic Castration-Resistant Prostate Cancer (808 citations)

What are the main themes of his work throughout his whole career to date?

Jeffrey Schlom mainly focuses on Immunology, Antigen, Monoclonal antibody, Cancer research and Immunotherapy. His Immunology research includes elements of Cancer and Cytotoxic T cell. Jeffrey Schlom interconnects Carcinoembryonic antigen, Radioimmunoassay, Tumor antigen and Virology in the investigation of issues within Antigen.

His Monoclonal antibody study incorporates themes from Molecular biology, In vivo and Pathology. His Molecular biology research includes themes of In vitro, Immunogen and Immunogenicity. His Cancer research research is multidisciplinary, incorporating perspectives in Cell culture, PD-L1, Cancer immunotherapy and Brachyury.

He most often published in these fields:

  • Immunology (35.24%)
  • Antigen (32.50%)
  • Monoclonal antibody (27.15%)

What were the highlights of his more recent work (between 2012-2021)?

  • Cancer research (26.03%)
  • Immunotherapy (24.91%)
  • Immune system (24.53%)

In recent papers he was focusing on the following fields of study:

His primary areas of study are Cancer research, Immunotherapy, Immune system, Immunology and Cancer. Jeffrey Schlom has included themes like Cytotoxic T cell, PD-L1, CD8 and Brachyury in his Cancer research study. His Immune system research is multidisciplinary, relying on both Antibody-dependent cell-mediated cytotoxicity, Antigen, Peripheral blood mononuclear cell, Combination therapy and Antibody.

Jeffrey Schlom studies Epitope which is a part of Antigen. His In vitro research extends to the thematically linked field of Immunology. His work carried out in the field of Cancer brings together such families of science as Acquired immune system and Oncology.

Between 2012 and 2021, his most popular works were:

  • Antibody-Dependent Cellular Cytotoxicity Activity of a Novel Anti-PD-L1 Antibody Avelumab (MSB0010718C) on Human Tumor Cells. (253 citations)
  • Avelumab for metastatic or locally advanced previously treated solid tumours (JAVELIN Solid Tumor): a phase 1a, multicohort, dose-escalation trial (163 citations)
  • Phase I Trial of M7824 (MSB0011359C), a Bifunctional Fusion Protein Targeting PD-L1 and TGFβ, in Advanced Solid Tumors (137 citations)

In his most recent research, the most cited papers focused on:

  • Cancer
  • Gene
  • Immune system

His scientific interests lie mostly in Immunotherapy, Immunology, Cancer research, Immune system and Cancer. His Immunotherapy study introduces a deeper knowledge of Internal medicine. His studies deal with areas such as In vitro and Brachyury as well as Immunology.

His Immune system research incorporates themes from Peripheral blood mononuclear cell, Antibody, Antigen and Carcinoembryonic antigen. His specific area of interest is Antibody, where Jeffrey Schlom studies Monoclonal antibody. His Antigen research incorporates elements of Prostate-specific antigen and Vaccination, Virology.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Radiation modulates the peptide repertoire, enhances MHC class I expression, and induces successful antitumor immunotherapy

Eric A. Reits;James W Hodge;Carla A Herberts;Tom A M Groothuis.
Journal of Experimental Medicine (2006)

1415 Citations

Rapid Tumor Penetration of a Single-Chain Fv and Comparison with Other Immunoglobulin Forms

Takashi Yokota;Diane E. Milenic;Marc Whitlow;Jeffrey Schlom.
Cancer Research (1992)

1264 Citations

Inhibition of CD4+25+ T regulatory cell function implicated in enhanced immune response by low-dose cyclophosphamide

M. E. Christine Lutsiak;Roshanak T. Semnani;Roberto De Pascalis;Syed V. S. Kashmiri.
Blood (2005)

1237 Citations

Overall Survival Analysis of a Phase II Randomized Controlled Trial of a Poxviral-Based PSA-Targeted Immunotherapy in Metastatic Castration-Resistant Prostate Cancer

Philip W. Kantoff;Thomas J. Schuetz;Brent A. Blumenstein;L. Michael Glode.
Journal of Clinical Oncology (2010)

1117 Citations

Grafting of “Abbreviated” Complementarity-Determining Regions Containing Specificity-Determining Residues Essential for Ligand Contact to Engineer a Less Immunogenic Humanized Monoclonal Antibody

Roberto De Pascalis;Makoto Iwahashi;Midori Tamura;Eduardo A. Padlan.
Journal of Immunology (2002)

945 Citations

A spectrum of monoclonal antibodies reactive with human mammary tumor cells

D Colcher;P H Hand;M Nuti;J Schlom.
Proceedings of the National Academy of Sciences of the United States of America (1981)

804 Citations

Generation of Human Cytotoxic T Cells Specific for Human Carcinoembryonic Antigen Epitopes From Patients Immunized With Recombinant Vaccinia-CEA Vaccine

Tsang Ky;Zaremba S;Nieroda Ca;Zhu Mz.
Journal of the National Cancer Institute (1995)

785 Citations

Differential reactivity of a novel monoclonal antibody (DF3) with human malignant versus benign breast tumors.

Donald Kufe;Giorgio Inghirami;Miyako Abe;Daniel Hayes.
Hybridoma (1984)

713 Citations

Distribution of Oncofetal Antigen Tumor-associated Glycoprotein-72 Defined by Monoclonal Antibody B72.3

Ann Thor;Noriaki Ohuchi;Cheryl A. Szpak;William W. Johnston.
Cancer Research (1986)

646 Citations

Analysis of a Human Tumor-associated Glycoprotein (TAG-72) Identified by Monoclonal Antibody B72.3

Virginia G. Johnson;Jeffrey Schlom;Andrew J. Paterson;Jeffrey Bennett.
Cancer Research (1986)

551 Citations

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