D-Index & Metrics Best Publications

D-Index & Metrics

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 132 Citations 56,793 558 World Ranking 157 National Ranking 116
Medicine D-index 111 Citations 42,263 484 World Ranking 2276 National Ranking 1331

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Cancer
  • Enzyme

Donald Kufe focuses on Molecular biology, Cancer research, Cell biology, Apoptosis and Immunology. His study in Molecular biology is interdisciplinary in nature, drawing from both DNA, DNA damage and Protein kinase C, Protein kinase A, Phosphorylation. The various areas that Donald Kufe examines in his Cancer research study include Tumor necrosis factor alpha, Cell culture, Ionizing radiation, MUC1 and Signal transduction.

Donald Kufe focuses mostly in the field of Signal transduction, narrowing it down to topics relating to Kinase and, in certain cases, Tyrosine kinase. His studies in Cell biology integrate themes in fields like Oxidative stress, Bcl-xL, Gene product and Heat shock protein. His Immunology study combines topics from a wide range of disciplines, such as Cytotoxic T cell and Radiation therapy.

His most cited work include:

  • Mucins in cancer: function, prognosis and therapy. (847 citations)
  • Blockade of the Vascular Endothelial Growth Factor Stress Response Increases the Antitumor Effects of Ionizing Radiation (806 citations)
  • Combined effects of angiostatin and ionizing radiation in antitumour therapy (622 citations)

What are the main themes of his work throughout his whole career to date?

Donald Kufe mostly deals with Cancer research, Molecular biology, Immunology, Cell biology and MUC1. He has researched Cancer research in several fields, including Tumor necrosis factor alpha, Apoptosis, Cancer and Signal transduction. His Molecular biology research includes themes of Cell culture, Gene expression, Biochemistry, DNA and Protein kinase C.

His Cell biology study frequently draws connections between related disciplines such as DNA damage. His work deals with themes such as Cancer cell, Breast cancer and Downregulation and upregulation, which intersect with MUC1. His research investigates the connection between Antigen and topics such as Monoclonal antibody that intersect with issues in Pathology.

He most often published in these fields:

  • Cancer research (38.72%)
  • Molecular biology (31.11%)
  • Immunology (18.69%)

What were the highlights of his more recent work (between 2013-2021)?

  • Cancer research (38.72%)
  • MUC1 (14.15%)
  • Immunology (18.69%)

In recent papers he was focusing on the following fields of study:

His primary scientific interests are in Cancer research, MUC1, Immunology, Downregulation and upregulation and Gene silencing. His Cancer research study integrates concerns from other disciplines, such as T cell, Immune system and Cancer. He interconnects Cell culture, Protein kinase B, Cancer cell, Molecular biology and Drug resistance in the investigation of issues within MUC1.

His research in Molecular biology tackles topics such as Signal transduction which are related to areas like Cell growth and Kinase. His Immunology research incorporates elements of In vivo and Myeloid-derived Suppressor Cell. His Downregulation and upregulation study combines topics from a wide range of disciplines, such as Apoptosis, Transcription factor, PD-L1 and Breast cancer, Triple-negative breast cancer.

Between 2013 and 2021, his most popular works were:

  • Holland-Frei Cancer Medicine (336 citations)
  • Individualized vaccination of AML patients in remission is associated with induction of antileukemia immunity and prolonged remissions. (89 citations)
  • MUC1-C oncoprotein activates the ZEB1/miR-200c regulatory loop and epithelial-mesenchymal transition. (77 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Cancer
  • Enzyme

His primary areas of investigation include Cancer research, MUC1, Downregulation and upregulation, Gene silencing and Molecular biology. His Cancer research study incorporates themes from Cell growth, Apoptosis, PD-L1, Signal transduction and Epigenetics. His MUC1 study combines topics in areas such as Cell culture, In vitro, Cancer cell, Transmembrane protein and Intracellular.

Donald Kufe combines subjects such as Protein kinase B and Triple-negative breast cancer with his study of Downregulation and upregulation. His studies deal with areas such as TCF4, SKBR3, microRNA, Breast cancer and Regulation of gene expression as well as Gene silencing. Donald Kufe regularly links together related areas like Colorectal cancer in his Molecular biology studies.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Mucins in cancer: function, prognosis and therapy.

Donald W. Kufe.
Nature Reviews Cancer (2009)

1128 Citations

Blockade of the Vascular Endothelial Growth Factor Stress Response Increases the Antitumor Effects of Ionizing Radiation

David H. Gorski;Michael A. Beckett;Nora T. Jaskowiak;Douglas P. Calvin.
Cancer Research (1999)

1086 Citations

Combined effects of angiostatin and ionizing radiation in antitumour therapy

Helena J. Mauceri;Nader N. Hanna;Michael A. Beckett;David H. Gorski.
Nature (1998)

831 Citations

Induction of antitumor activity by immunization with fusions of dendritic and carcinoma cells.

Jlanlin Gong;Dongshu Chen;Masahiro Kashiwaba;Donald Kufe.
Nature Medicine (1997)

732 Citations

p73 is regulated by tyrosine kinase c-Abl in the apoptotic response to DNA damage

Zhi-Min Yuan;Hisashi Shioya;Takatoshi Ishiko;Xiangao Sun.
Nature (1999)

728 Citations

Negative regulation of cytochrome c‐mediated oligomerization of Apaf‐1 and activation of procaspase‐9 by heat shock protein 90

Pramod Pandey;Ayman Saleh;Atsuko Nakazawa;Shailendra Kumar.
The EMBO Journal (2000)

691 Citations

Differential reactivity of a novel monoclonal antibody (DF3) with human malignant versus benign breast tumors.

Donald Kufe;Giorgio Inghirami;Miyako Abe;Daniel Hayes.
Hybridoma (1984)

686 Citations

Activation of the c-Abl tyrosine kinase in the stress response to DMA-damaging agents

Surender Kharbanda;Ruibao Ren;Pramod Pandey;Timothy D. Shafman.
Nature (1995)

617 Citations

Interaction between ATM protein and c-Abl in response to DNA damage

T Shafman;K K Khanna;P Kedar;K Spring.
Nature (1997)

589 Citations

Proteolytic Activation of Protein Kinase C δ by an ICE/CED 3-like Protease Induces Characteristics of Apoptosis

Tariq Ghayur;Margaret Hugunin;Robert V. Talanian;Sheldon Ratnofsky.
Journal of Experimental Medicine (1996)

587 Citations

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