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D-Index & Metrics

Biology and Biochemistry

D-Index
151
Citations
74601
World Ranking
174
National Ranking
121

Medicine

D-Index
151
Citations
74527
World Ranking
1129
National Ranking
650

Overview

Donald Kufe is affiliated with Harvard University in the United States and has contributed extensively to research in medicine and biochemistry, genetics, and molecular biology.

Their work spans several subfields, including molecular biology, oncology, immunology, pulmonary and respiratory medicine, and cancer research. Their main research topics focus on:

  • RNA modifications and cancer
  • Immunotherapy and immune responses
  • CAR-T cell therapy research
  • Glycosylation and glycoproteins research
  • RNA interference and gene delivery
  • Cancer cells and metastasis
  • Cancer immunotherapy and biomarkers

Donald Kufe has published in a variety of scientific journals. Frequent publication venues include:

  • Cancer Research
  • Blood
  • Transplantation and Cellular Therapy
  • Oncogene
  • Journal for ImmunoTherapy of Cancer

Some of the recent papers attributed to or closely associated with Donald Kufe's research are:

  • MUC1-C regulates lineage plasticity driving progression to neuroendocrine prostate cancer (2020, Nature Communications)
  • MUC1-C in chronic inflammation and carcinogenesis; emergence as a target for cancer treatment (2020, Carcinogenesis)
  • MUC1-C Activates the BAF (mSWI/SNF) Complex in Prostate Cancer Stem Cells (2020, Cancer Research)
  • MUC1-C integrates activation of the IFN-γ pathway with suppression of the tumor immune microenvironment in triple-negative breast cancer (2021, Journal for ImmunoTherapy of Cancer)
  • MUC1-C activates the PBAF chromatin remodeling complex in integrating redox balance with progression of human prostate cancer stem cells (2021, Oncogene)

Frequent collaborators in their research include:

  • Atrayee Bhattacharya
  • Nami Yamashita
  • Atsushi Fushimi
  • Yoshihiro Morimoto
  • Jacalyn Rosenblatt

Best Publications

  • Mucins in cancer: function, prognosis and therapy.

    Donald W. Kufe

  • Blockade of the Vascular Endothelial Growth Factor Stress Response Increases the Antitumor Effects of Ionizing Radiation

    David H. Gorski;Michael A. Beckett;Nora T. Jaskowiak;Douglas P. Calvin

  • Combined effects of angiostatin and ionizing radiation in antitumour therapy

    Helena J. Mauceri;Nader N. Hanna;Michael A. Beckett;David H. Gorski

  • p73 is regulated by tyrosine kinase c-Abl in the apoptotic response to DNA damage

    Zhi-Min Yuan;Hisashi Shioya;Takatoshi Ishiko;Xiangao Sun

  • Induction of antitumor activity by immunization with fusions of dendritic and carcinoma cells.

    Jlanlin Gong;Dongshu Chen;Masahiro Kashiwaba;Donald Kufe

  • Negative regulation of cytochrome c‐mediated oligomerization of Apaf‐1 and activation of procaspase‐9 by heat shock protein 90

    Pramod Pandey;Ayman Saleh;Atsuko Nakazawa;Shailendra Kumar

  • Differential reactivity of a novel monoclonal antibody (DF3) with human malignant versus benign breast tumors.

    Donald Kufe;Giorgio Inghirami;Miyako Abe;Daniel Hayes

  • Holland-Frei Cancer Medicine

    Donald W Kufe;Raphael E Pollock;Ralph R Weichselbaum;Robert C Bast

  • Activation of the c-Abl tyrosine kinase in the stress response to DNA-damaging agents

    Surender Kharbanda;Ruibao Ren;Pramod Pandey;Timothy D. Shafman

  • Interaction between ATM protein and c-Abl in response to DNA damage

    T Shafman;K K Khanna;P Kedar;K Spring

  • Proteolytic Activation of Protein Kinase C δ by an ICE/CED 3-like Protease Induces Characteristics of Apoptosis

    Tariq Ghayur;Margaret Hugunin;Robert V. Talanian;Sheldon Ratnofsky

  • Anti-angiogenic cues from vascular basement membrane collagen.

    Pablo C. Colorado;Adriana Torre;George Kamphaus;Yohei Maeshima

  • Serotherapy of a Patient with a Monoclonal Antibody Directed against a Human Lymphoma-associated Antigen

    Lee M. Nadler;Philip Stashenko;Russell Hardy;William D. Kaplan

  • Ionizing radiation induces expression and binding activity of the nuclear factor kappa B.

    Marion A. Brach;Ralf Hass;Matthew L. Sherman;Hisato Gunji

  • Translocation of SAPK/JNK to Mitochondria and Interaction with Bcl-xL in Response to DNA Damage

    Surender Kharbanda;Satya Saxena;Kiyotsugu Yoshida;Pramod Pandey

  • Increased tumor necrosis factor alpha mRNA after cellular exposure to ionizing radiation

    Dennis E. Hallahan;David R. Spriggs;Michael A. Beckett;Donald W. Kufe

  • Role for Bcl-xL as an inhibitor of cytosolic cytochrome C accumulation in DNA damage-induced apoptosis

    Surender Kharbanda;Pramod Pandey;Lesley Schofield;Sara Israels

  • Correlation of cytotoxicity with incorporation of ara-C into DNA.

    D W Kufe;P P Major;E M Egan;G P Beardsley

  • Fusion cell vaccination of patients with metastatic breast and renal cancer induces immunological and clinical responses.

    David Avigan;Baldev Vasir;Jianlin Gong;Virginia Borges

  • MUC1-C oncoprotein as a target in breast cancer: activation of signaling pathways and therapeutic approaches

    Donald W. Kufe

Frequent Co-Authors

Ralph R. Weichselbaum
Ralph R. Weichselbaum University of Chicago
Surender Kharbanda
Surender Kharbanda Harvard University
Richard Stone
Richard Stone Harvard University
Zhi-Min Yuan
Zhi-Min Yuan Harvard University
Jianlin Gong
Jianlin Gong Boston University
Vikas P. Sukhatme
Vikas P. Sukhatme Emory University
Kenneth C. Anderson
Kenneth C. Anderson Harvard University
Dennis E. Hallahan
Dennis E. Hallahan Washington University in St. Louis
Vassiliki A. Boussiotis
Vassiliki A. Boussiotis Beth Israel Deaconess Medical Center
Paul G. Richardson
Paul G. Richardson Harvard University

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