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Surender Kharbanda

Surender Kharbanda

D-Index & Metrics

Biology and Biochemistry

D-Index
88
Citations
25975
World Ranking
2718
National Ranking
1409

Overview

Surender Kharbanda is affiliated with Harvard University in the United States and specializes in research that intersects biochemistry, genetics, molecular biology, and medicine. Their work primarily spans molecular biology and oncology, with additional focus on biomedical engineering, biomaterials, and biotechnology.

The scientist's research topics cover various aspects of cancer biology and treatment strategies, including:

  • Cancer Cells and Metastasis
  • Histone Deacetylase Inhibitors Research
  • Nanoplatforms for cancer theranostics
  • Nanoparticle-Based Drug Delivery
  • Glycosylation and Glycoproteins Research
  • Protein Degradation and Inhibitors
  • Cancer Research and Treatments

Many of their publications appear in journals that focus on oncology and pharmaceutical sciences. Frequent publication venues for Kharbanda include:

  • Cancer Research
  • International Journal of Pharmaceutics
  • Journal of Clinical Oncology
  • Faculty Opinions - Post-Publication Peer Review of the Biomedical Literature
  • Nanomedicine

Notable recent papers feature topics such as drug development targeting PI3K/HDAC pathways, cancer stemness mechanisms, and nanoparticle-based cancer therapies. Examples of such work are:

  • Design, Synthesis, and Biological Evaluation of Quinazolin-4-one-Based Hydroxamic Acids as Dual PI3K/HDAC Inhibitors (2020, Journal of Medicinal Chemistry)
  • MUC1-C drives stemness in progression of colitis to colorectal cancer (2020, JCI Insight)
  • Peptide-Based Combination Nanoformulations for Cancer Therapy (2020, Nanomedicine)
  • Polylactic acid based polymeric nanoparticle mediated co-delivery of navitoclax and decitabine for cancer therapy (2022, Nanomedicine Nanotechnology Biology and Medicine)
  • Polylactic acid based biodegradable hybrid block copolymeric nanoparticle mediated co-delivery of salinomycin and doxorubicin for cancer therapy (2023, International Journal of Pharmaceutics)

The scientist frequently collaborates with peers including Harpal Singh, Sachchidanand Tiwari, Neha Mehrotra, Mohd Anees, and Anees Mohammad. These collaborations have contributed substantially to their publication record.

Best Publications

  • Proteolytic activation of protein kinase C delta by an ICE-like protease in apoptotic cells.

    Y Emoto;Y Manome;G Meinhardt;H Kisaki

  • p73 is regulated by tyrosine kinase c-Abl in the apoptotic response to DNA damage

    Zhi-Min Yuan;Hisashi Shioya;Takatoshi Ishiko;Xiangao Sun

  • Negative regulation of cytochrome c‐mediated oligomerization of Apaf‐1 and activation of procaspase‐9 by heat shock protein 90

    Pramod Pandey;Ayman Saleh;Atsuko Nakazawa;Shailendra Kumar

  • Apoptosis in heart failure: Release of cytochrome c from mitochondria and activation of caspase-3 in human cardiomyopathy

    Jagat Narula;Pramod Pandey;Eloisa Arbustini;Nezam Haider

  • Activation of the c-Abl tyrosine kinase in the stress response to DNA-damaging agents

    Surender Kharbanda;Ruibao Ren;Pramod Pandey;Timothy D. Shafman

  • Interaction between ATM protein and c-Abl in response to DNA damage

    T Shafman;K K Khanna;P Kedar;K Spring

  • Proteolytic Activation of Protein Kinase C δ by an ICE/CED 3-like Protease Induces Characteristics of Apoptosis

    Tariq Ghayur;Margaret Hugunin;Robert V. Talanian;Sheldon Ratnofsky

  • Tumstatin, an Endothelial Cell-Specific Inhibitor of Protein Synthesis

    Yohei Maeshima;Akulapalli Sudhakar;Julie C. Lively;Kohjiro Ueki

  • Translocation of SAPK/JNK to Mitochondria and Interaction with Bcl-xL in Response to DNA Damage

    Surender Kharbanda;Satya Saxena;Kiyotsugu Yoshida;Pramod Pandey

  • Role for Bcl-xL as an inhibitor of cytosolic cytochrome C accumulation in DNA damage-induced apoptosis

    Surender Kharbanda;Pramod Pandey;Lesley Schofield;Sara Israels

  • Mitochondrial Translocation of Protein Kinase C δ in Phorbol Ester-induced Cytochrome c Release and Apoptosis

    Pradip K. Majumder;Pramod Pandey;Xiangao Sun;Keding Cheng

  • Hsp27 functions as a negative regulator of cytochrome c-dependent activation of procaspase-3

    Pramod Pandey;Rebecca Farber;Atsuko Nakazawa;Shailendra Kumar

  • Human MUC1 carcinoma-associated protein confers resistance to genotoxic anticancer agents.

    Jian Ren;Naoki Agata;Dongshu Chen;Yongqing Li

  • Interleukin-6 Inhibits Fas-Induced Apoptosis and Stress-Activated Protein Kinase Activation in Multiple Myeloma Cells

    Dharminder Chauhan;Surender Kharbanda;Atsushi Ogata;Mitsuyoshi Urashima

  • Triterpenoid CDDO-Me Blocks the NF-κB Pathway by Direct Inhibition of IKKβ on Cys-179

    Rehan Ahmad;Deepak Raina;Colin Meyer;Surender Kharbanda

  • Identification of the anti-angiogenic site within vascular basement membrane-derived tumstatin.

    Yohei Maeshima;Mark Manfredi;Corinne Reimer;Kathryn A. Holthaus

  • Functional interaction between DNA-PK and c-Abl in response to DNA damage

    Surender Kharbanda;Pramod Pandey;Shengfang Jin;Satoshi Inoue

  • Role for c-Abl tyrosine kinase in growth arrest response to DNA damage

    Zhi-Min Yuan;Yinyin Huang;Young Whang;Charles Sawyers

  • MUC1 Oncoprotein Blocks Glycogen Synthase Kinase 3β–Mediated Phosphorylation and Degradation of β-Catenin

    Lei Huang;Dongshu Chen;Derek Liu;Li Yin

  • Extracellular Matrix-derived Peptide Binds to αvβ3 Integrin and Inhibits Angiogenesis

    Yohei Maeshima;Udaya L. Yerramalla;Mohanraj Dhanabal;Kathryn A. Holthaus

Frequent Co-Authors

Donald Kufe
Donald Kufe Harvard University
Ralph R. Weichselbaum
Ralph R. Weichselbaum University of Chicago
Zhi-Min Yuan
Zhi-Min Yuan Harvard University
Eric J. Rubin
Eric J. Rubin Harvard University
Pramod K. Pandey
Pramod K. Pandey University of California, Davis
Dharminder Chauhan
Dharminder Chauhan Harvard University
Ralf Hass
Ralf Hass Hannover Medical School
Richard Stone
Richard Stone Harvard University
Kenneth C. Anderson
Kenneth C. Anderson Harvard University
Vikas P. Sukhatme
Vikas P. Sukhatme Emory University

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