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Neuroscience

D-Index
44
Citations
7764
World Ranking
7155
National Ranking
320

Overview

Marc Savasta is affiliated with Grenoble Alpes University in France, specializing in the medical and neuroscience fields. Their research primarily focuses on neurological disorders, especially Parkinson's Disease, and the related mechanisms and treatments.

The main fields of study for Savasta include Medicine and Neuroscience, with a particular emphasis on subfields such as Neurology, Cellular and Molecular Neuroscience, Clinical Psychology, Genetics, and Molecular Biology.

Their scholarly work addresses multiple topics, including:

  • Neurological disorders and treatments
  • Parkinson's Disease Mechanisms and Treatments
  • Neurotransmitter Receptor Influence on Behavior
  • Transcranial Magnetic Stimulation Studies
  • Obsessive-Compulsive Spectrum Disorders
  • Eating Disorders and Behaviors
  • Genetics and Neurodevelopmental Disorders

Savasta has contributed articles to several frequent publication venues:

  • Movement Disorders
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Current topics in behavioral neurosciences
  • Translational Psychiatry
  • European Journal of Neuroscience

Notable recent papers authored or co-authored by Savasta include:

  • Subthalamic Nucleus Stimulation Impairs Motivation: Implication for Apathy in Parkinson's Disease, 2020, Movement Disorders
  • Dopamine D3 Receptors: A Potential Target to Treat Motivational Deficits in Parkinson's Disease, 2022, Current topics in behavioral neurosciences
  • Pramipexole restores behavioral inhibition in highly impulsive rats through a paradoxical modulation of frontostriatal networks, 2024, Translational Psychiatry
  • Unilateral and Bilateral Subthalamic stimulation differently promote apathy: a translational approach, 2020, bioRxiv (Cold Spring Harbor Laboratory)
  • Reply to: Letter to the Editor by Martínez-Fernández, 2020, Movement Disorders

Collaborations have been a significant aspect of Savasta's research career. Frequent co-authors include:

  • Carole Carcenac
  • Sébastien Carnicella
  • Yvan M. Vachez
  • Robin Magnard
  • Sabrina Boulet

Best Publications

  • Uncovering the mechanism(s) of action of deep brain stimulation: activation, inhibition, or both

    Cameron C McIntyre;Marc Savasta;Lydia Kerkerian-Le Goff;Jerrold L Vitek

  • Non-motor dopamine withdrawal syndrome after surgery for Parkinson's disease: predictors and underlying mesolimbic denervation

    Stéphane Thobois;Claire Ardouin;Claire Ardouin;Eugénie Lhommée;Eugénie Lhommée;Hélène Klinger;Hélène Klinger

  • How does deep brain stimulation work? Present understanding and future questions.

    Cameron C. McIntyre;Marc Savasta;Benjamin L. Walter;Jerrold L. Vitek

  • Effects of high frequency stimulation of subthalamic nucleus on extracellular glutamate and GABA in substantia nigra and globus pallidus in the normal rat

    François Windels;Nicolas Bruet;Annie Poupard;Nadia Urbain

  • Autoradiographic localization of D1 dopamine receptors in the rat brain with [3H]SCH 23390.

    Marc Savasta;Alain Dubois;Bernard Scatton

  • Autoradiographic distribution of the D1 agonist [3H]SKF 38393, in the rat brain and spinal cord. Comparison with the distribution of D2 dopamine receptors.

    A. Dubois;M. Savasta;O. Curet;B. Scatton

  • Influence of the frequency parameter on extracellular glutamate and γ‐aminobutyric acid in substantia nigra and globus pallidus during electrical stimulation of subthalamic nucleus in rats

    François Windels;Nicolas Bruet;Annie Poupard;Claude Feuerstein

  • Loss of dopaminergic nigrostriatal neurons accounts for the motivational and affective deficits in Parkinson's disease

    Guillaume Drui;Sébastien Carnicella;Carole Carcenac;Matthieu Favier

  • High frequency stimulation of the subthalamic nucleus increases the extracellular contents of striatal dopamine in normal and partially dopaminergic denervated rats

    Nicolas Bruet;François Windels;Anne Bertrand;Claude Feuerstein

  • A new model to study compensatory mechanisms in MPTP-treated monkeys exhibiting recovery

    Stéphanie Mounayar;Sabrina Boulet;Dominique Tandé;Caroline Jan

  • Pallidal Origin of GABA Release within the Substantia Nigra Pars Reticulata during High-Frequency Stimulation of the Subthalamic Nucleus

    François Windels;Carole Carcenac;Annie Poupard;Marc Savasta

  • Different plasticity changes in D1 and D2 receptors in rat striatal subregions following impairment of dopaminergic transmission

    Marc Savasta;Alain Dubois;Jesùs Benavidès;Bernard Scatton

  • Distinct changes in cAMP and extracellular signal-regulated protein kinase signalling in L-DOPA-induced dyskinesia.

    Emanuela Santini;Veronique Sgambato-Faure;Veronique Sgambato-Faure;Qin Li;Qin Li;Marc Savasta

  • Normal distribution of alpha 2-adrenoceptors in the rat spinal cord and its modification after noradrenergic denervation: a quantitative autoradiographic study.

    C. Roudet;P. Mouchet;C. Feuerstein;M. Savasta

  • Unrelated course of subthalamic nucleus and globus pallidus neuronal activities across vigilance states in the rat.

    Nadia Urbain;Damien Gervasoni;Fabienne Soulière;Letícia Lobo

  • Behavioral Recovery in MPTP-Treated Monkeys: Neurochemical Mechanisms Studied by Intrastriatal Microdialysis

    Sabrina Boulet;Stéphanie Mounayar;Annie Poupard;Anne Bertrand

  • Subthalamic stimulation-induced forelimb dyskinesias are linked to an increase in glutamate levels in the substantia nigra pars reticulata.

    Sabrina Boulet;Emilie Lacombe;Carole Carcenac;Claude Feuerstein

  • Denervation supersensitivity of striatal D2 dopamine receptors is restricted to the ventro- and dorsolateral regions of the striatum.

    Marc Savasta;Alain Dubois;Claude Feuerstein;Monique Manier

  • Evidence for dopamine D2 receptor mRNA expression by striatal astrocytes in culture: in situ hybridization and polymerase chain reaction studies.

    Anna Bal;Thomas Bachelot;Marc Savasta;Monique Manier

  • Intrastriatal dopamine-rich implants reverse the changes in dopamine D2 receptor densities caused by 6-hydroxydopamine lesion of the nigrostriatal pathway in rats: an autoradiographic study.

    M. Savasta;F. Mennicken;M. Chritin;D.N. Abrous

  • High Frequency Stimulation of the Subthalamic Nucleus

    Nicolas Maurice;Jean-Michel Deniau;Bertrand Degos;François Windels

Frequent Co-Authors

Claude Feuerstein
Claude Feuerstein Joseph Fourier University
Guadalupe Mengod
Guadalupe Mengod Spanish National Research Council
Olivier David
Olivier David Grenoble Alpes University
Rita Raisman-Vozari
Rita Raisman-Vozari Université Paris Cité
Paul Krack
Paul Krack University of Bern
Yves Agid
Yves Agid Institut du Cerveau
Paul G. Overton
Paul G. Overton University of Sheffield
Emmanuel Broussolle
Emmanuel Broussolle Centre national de la recherche scientifique, CNRS
Valérie Fraix
Valérie Fraix Grenoble Alpes University
Etienne C. Hirsch
Etienne C. Hirsch Sorbonne University

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