D-Index & Metrics Best Publications
Research.com 2022 Best Scientist Award Badge

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Medicine D-index 143 Citations 86,977 340 World Ranking 568 National Ranking 344
Best Scientists D-index 172 Citations 125,065 577 World Ranking 568 National Ranking 383

Research.com Recognitions

Awards & Achievements

2022 - Research.com Best Scientist Award

1998 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Enzyme
  • Cancer

Michael B. Sporn mainly investigates Transforming growth factor, Transforming growth factor beta, Cell biology, Internal medicine and Endocrinology. His work deals with themes such as Cell culture, Epidermal growth factor, Biochemistry, Molecular biology and Growth factor, which intersect with Transforming growth factor. His study explores the link between Transforming growth factor beta and topics such as Pathology that cross with problems in Cancer research.

As part of the same scientific family, Michael B. Sporn usually focuses on Cell biology, concentrating on Immunology and intersecting with Endothelium. As part of his studies on Internal medicine, Michael B. Sporn frequently links adjacent subjects like Binding protein. His Endocrinology research is multidisciplinary, incorporating perspectives in Retinoid, Autocrine signalling, Carcinogenesis, Tamoxifen and In vivo.

His most cited work include:

  • Transforming growth factor type beta: rapid induction of fibrosis and angiogenesis in vivo and stimulation of collagen formation in vitro. (2521 citations)
  • Transforming growth factor beta. (2041 citations)
  • Transforming growth factor beta 1 null mutation in mice causes excessive inflammatory response and early death. (1652 citations)

What are the main themes of his work throughout his whole career to date?

His scientific interests lie mostly in Transforming growth factor, Internal medicine, Biochemistry, Molecular biology and Cancer research. Michael B. Sporn usually deals with Transforming growth factor and limits it to topics linked to Growth factor and Epidermal growth factor. His Internal medicine study incorporates themes from Endocrinology and Oncology.

His studies deal with areas such as Cell culture and RNA, Messenger RNA, Gene expression, Gene as well as Molecular biology. His Cancer research study combines topics in areas such as Apoptosis and Immunology. His study in Transforming growth factor beta is interdisciplinary in nature, drawing from both Peptide sequence and Autocrine signalling.

He most often published in these fields:

  • Transforming growth factor (22.90%)
  • Internal medicine (21.42%)
  • Biochemistry (20.92%)

What were the highlights of his more recent work (between 2006-2020)?

  • Cancer research (19.28%)
  • Pharmacology (8.57%)
  • Cancer (12.36%)

In recent papers he was focusing on the following fields of study:

His primary scientific interests are in Cancer research, Pharmacology, Cancer, Immunology and Triterpenoid. His Cancer research research includes elements of Endocrinology, Pancreatic cancer, Immune system, Cell cycle and Breast cancer. His Pharmacology research is multidisciplinary, relying on both Apoptosis, Biochemistry, Carcinogen, Lung and In vivo.

His research in Apoptosis intersects with topics in Cancer cell, Cell culture, Nitric oxide synthase and Molecular biology. The subject of his Cancer research is within the realm of Internal medicine. His study ties his expertise on Oncology together with the subject of Internal medicine.

Between 2006 and 2020, his most popular works were:

  • The tumour microenvironment as a target for chemoprevention (635 citations)
  • NRF2 and cancer: the good, the bad and the importance of context (631 citations)
  • Triterpenoids and rexinoids as multifunctional agents for the prevention and treatment of cancer (504 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • Cancer

Michael B. Sporn spends much of his time researching Pharmacology, Oxidative stress, Immunology, Biochemistry and Cancer research. His Pharmacology study combines topics from a wide range of disciplines, such as Tumor necrosis factor alpha, Oleanolic acid, Reactive oxygen species, Downregulation and upregulation and Receptor. His Biochemistry study frequently draws connections between related disciplines such as In vivo.

Michael B. Sporn has included themes like Endocrinology, Internal medicine, Angiogenesis and Bardoxolone methyl in his In vivo study. His Endocrinology research includes themes of Fatty acid synthesis and Cell type. Michael B. Sporn combines subjects such as Retinal degeneration, Pancreatic cancer, Retinal pigment epithelium, Neuroinflammation and Signal transduction with his study of Cancer research.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Transforming growth factor type beta: rapid induction of fibrosis and angiogenesis in vivo and stimulation of collagen formation in vitro.

A B Roberts;M B Sporn;R K Assoian;J M Smith.
Proceedings of the National Academy of Sciences of the United States of America (1986)

3473 Citations

Transforming growth factor beta.

Roberts Ab;Sporn Mb.
Advances in Cancer Research (1988)

3332 Citations

Human transforming growth factor-beta complementary DNA sequence and expression in normal and transformed cells.

Rik Derynck;Julie A. Jarrett;Ellson Y. Chen;Dennis H. Eaton.
Nature (1985)

2397 Citations

Transforming growth factor beta 1 null mutation in mice causes excessive inflammatory response and early death.

Ashok B. Kulkarni;Chang-Goo Huh;Dean Becker;Andrew Geiser.
Proceedings of the National Academy of Sciences of the United States of America (1993)

2241 Citations

Can dietary beta-carotene materially reduce human cancer rates?

R. Peto;R. Doll;J. D. Buckley;M. B. Sporn.
Nature (1981)

2103 Citations

Transforming growth factor-beta in human platelets. Identification of a major storage site, purification, and characterization.

R K Assoian;A Komoriya;C A Meyers;D M Miller.
Journal of Biological Chemistry (1983)

2046 Citations

Autocrine growth factors and cancer.

Michael B. Sporn;Anita B. Roberts.
Nature (1985)

1990 Citations

Production of transforming growth factor beta by human T lymphocytes and its potential role in the regulation of T cell growth.

John H. Kehrl;Lalage M. Wakefield;Anita B. Roberts;Sonia Jakowlew.
Journal of Experimental Medicine (1986)

1982 Citations

The Retinoids : biology, chemistry, and medicine

Michael B. Sporn;Anita B. Roberts;DeWitt S. Goodman.
(1994)

1981 Citations

Autocrine Secretion and Malignant Transformation of Cells

Michael B. Sporn;George J. Todaro.
The New England Journal of Medicine (1980)

1916 Citations

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