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Biology and Biochemistry

D-Index
65
Citations
12962
World Ranking
9300
National Ranking
4106

Overview

David Danielpour is affiliated with Case Western Reserve University in the United States and specializes in research spanning biochemistry, genetics, molecular biology, and medicine. Their work predominantly focuses on molecular biology and oncology, with particular emphasis on signaling pathways and cancer-related gene regulation.

Their recent publications include:

  • Advances and Challenges in Targeting TGF-β Isoforms for Therapeutic Intervention of Cancer: A Mechanism-Based Perspective, 2024, published in Pharmaceuticals
  • Jagged-1 is induced by mTOR inhibitors in renal cancer cells through an Akt/ALK5/Smad4-dependent mechanism, 2022, published in Current Research in Pharmacology and Drug Discovery
  • Hypoxia represses early responses of prostate and renal cancer cells to YM155 independent of HIF-1α and HIF-2α, 2021, published in Current Research in Pharmacology and Drug Discovery

Frequent coauthors collaborating with Danielpour include:

  • Sarah Corum
  • Kyung Song
  • Tracy L. Krebs
  • William E. Samsa
  • Murali K. Mamidi

Their publications appear most often in the following venues:

  • Oncogene
  • Current Research in Pharmacology and Drug Discovery
  • Pharmaceuticals
  • Cancer Research

Main research fields encompass:

  • Biochemistry, Genetics and Molecular Biology
  • Medicine

Key subfields addressed in their work are:

  • Molecular Biology
  • Oncology
  • Immunology
  • Cancer Research
  • Pulmonary and Respiratory Medicine

Primary research topics covered by Danielpour include:

  • TGF-β signaling in diseases
  • Cancer-related gene regulation
  • Cancer Cells and Metastasis
  • Ubiquitin and proteasome pathways
  • Protein Degradation and Inhibitors
  • Interferon and immune responses
  • PI3K/AKT/mTOR signaling in cancer

Best Publications

  • Immunodetection and quantitation of the two forms of transforming growth factor‐beta (TGF‐β1 and TGF‐β2) secreted by cells in culture

    David Danielpour;Linda L. Dart;Kathleen C. Flanders;Anita B. Roberts

  • Mesoderm induction in amphibians: the role of TGF-beta 2-like factors

    Frédéric Rosa;Anita B. Roberts;David Danielpour;Linda L. Dart

  • EphA2 Mediates Ligand-Dependent Inhibition and Ligand-Independent Promotion of Cell Migration and Invasion via a Reciprocal Regulatory Loop with Akt

    Hui Miao;Da Qiang Li;Amitava Mukherjee;Hong Guo

  • Retinoic acid induces transforming growth factor-beta 2 in cultured keratinocytes and mouse epidermis.

    A. B. Glick;K. C. Flanders;D. Danielpour;S. H. Yuspa

  • TGF-β upregulates miR-181a expression to promote breast cancer metastasis

    Molly A. Taylor;Khalid Sossey-Alaoui;Cheryl L. Thompson;David Danielpour

  • Transactivation of the transforming growth factor beta 1 (TGF-beta 1) gene by human T lymphotropic virus type 1 tax: a potential mechanism for the increased production of TGF-beta 1 in adult T cell leukemia.

    Seong Jin Kim;John H. Kehrl;Jack Burton;Craig L. Tendler

  • An Anti–Transforming Growth Factor β Antibody Suppresses Metastasis via Cooperative Effects on Multiple Cell Compartments

    Jeong Seok Nam;Masaki Terabe;Mizuko Mamura;Mizuko Mamura;Mi Jin Kang

  • A novel mitochondrial septin-like protein, ARTS, mediates apoptosis dependent on its P-loop motif.

    Sarit Larisch;Youngsuk Yi;Rona Lotan;Hedviga Kerner

  • Hypoxia upregulates the synthesis of tgf-β1 by human dermal fibroblasts

    Vincent Falanga;Su Wen Qian;David Danielpour;Matthew H Katz

  • Ski acts as a co-repressor with Smad2 and Smad3 to regulate the response to type β transforming growth factor

    Weidong Xu;Konstantina Angelis;David Danielpour;Maher M. Haddad

  • The androgen receptor represses transforming growth factor-β signaling through interaction with Smad3

    Jerry E. Chipuk;Susan C. Cornelius;Nicole J. Pultz;Joan S. Jorgensen

  • Regulation of alveolar macrophage transforming growth factor-beta secretion by corticosteroids in bleomycin-induced pulmonary inflammation in the rat.

    Nasreen Khalil;Carol Whitman;Li Zuo;David Danielpour

  • Novel roles of Akt and mTOR in suppressing TGF-β/ALK5-mediated Smad3 activation

    Kyung Song;Hui Wang;Tracy L Krebs;David Danielpour

  • Differential inhibition of transforming growth factor beta 1 and beta 2 activity by alpha 2-macroglobulin.

    David Danielpour;Michael B. Sporn

  • Human cytomegalovirus infection induces transcription and secretion of transforming growth factor beta 1.

    S. Michelson;J. Alcami;S. J. Kim;David Danielpour

  • Sandwich Enzyme-Linked Immunosorbent Assays (Selisas) Quantitate and Distinguish Two Forms of Transforming Growth Factor-Beta (TGF-β1 and TGF-β2) in Complex Biological Fluids

    David Danielpour;Kyung Young Kim;Linda L. Dart;Shinichi Watanabe

  • Transforming growth factor-beta (TGF-beta) isoforms in rat liver regeneration: messenger RNA expression and activation of latent TGF-beta.

    Sonia B. Jakowlew;Janet E. Mead;David Danielpour;Justina Wu

  • Regulation of Apoptosis Induced by Transforming Growth Factor-β1 in Nontumorigenic and Tumorigenic Rat Prostatic Epithelial Cell Lines

    Andrew Y. Hsing;Kenji Kadomatsu;Kenji Kadomatsu;Michael J. Bonham;David Danielpour

  • Transforming growth factor-β in calf articular cartilage organ cultures: Synthesis and distribution

    T. I. Morales;M. E. Joyce;M. E. Sobel;David Danielpour

  • The growth inhibition of human breast cancer cells by a novel synthetic progestin involves the induction of transforming growth factor beta.

    Anthony A. Colletta;Lalage M. Wakefield;Fiona V. Howell;David Danielpour

Frequent Co-Authors

Michael B. Sporn
Michael B. Sporn Dartmouth College
Anita B. Roberts
Anita B. Roberts National Institutes of Health
Seong-Jin Kim
Seong-Jin Kim Seoul National University
Sally L. Dunwoodie
Sally L. Dunwoodie Victor Chang Cardiac Research Institute
Kathleen C. Flanders
Kathleen C. Flanders National Institutes of Health
Adam B. Glick
Adam B. Glick Pennsylvania State University
Paturu Kondaiah
Paturu Kondaiah Indian Institute of Science
Michael A. O'Reilly
Michael A. O'Reilly The University of Texas MD Anderson Cancer Center
Igor B. Dawid
Igor B. Dawid National Institutes of Health
Kenji Kadomatsu
Kenji Kadomatsu Nagoya University

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