D-Index & Metrics Best Publications

D-Index & Metrics

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Medicine D-index 72 Citations 21,804 120 World Ranking 13799 National Ranking 7250

Overview

What is she best known for?

The fields of study she is best known for:

  • Gene
  • Cancer
  • Enzyme

Kathleen C. Flanders mainly focuses on Transforming growth factor beta, Transforming growth factor, Cell biology, Extracellular matrix and Biochemistry. Kathleen C. Flanders combines subjects such as Immunohistochemistry, Molecular biology and Growth factor with her study of Transforming growth factor beta. Her Transforming growth factor study combines topics in areas such as Peripheral nervous system, Cancer research, Nervous system and TGF alpha.

Her Cell biology research incorporates themes from Integrin and Cartilage, Anatomy. Her work deals with themes such as Fibrosis, Pathology, Collagen biosynthesis and Mesenchyme, which intersect with Extracellular matrix. Kathleen C. Flanders has researched Biochemistry in several fields, including Cell culture and Polyclonal antibodies.

Her most cited work include:

  • Transforming growth factor beta 1 null mutation in mice causes excessive inflammatory response and early death. (1652 citations)
  • Evidence that transforming growth factor-β is a hormonally regulated negative growth factor in human breast cancer cells (915 citations)
  • Role of transforming growth factor-beta in the development of the mouse embryo. (662 citations)

What are the main themes of her work throughout her whole career to date?

Her main research concerns Transforming growth factor, Transforming growth factor beta, Internal medicine, Cell biology and Endocrinology. Her biological study spans a wide range of topics, including Gene expression, Cytokine, Wound healing, Pathology and Molecular biology. Her research integrates issues of Immunohistochemistry, Immunology, Cancer research, Growth factor and Extracellular matrix in her study of Transforming growth factor beta.

The study incorporates disciplines such as Andrology, Cartilage and Northern blot in addition to Internal medicine. Her research investigates the connection with Cell biology and areas like Cell growth which intersect with concerns in Cell culture. Kathleen C. Flanders works mostly in the field of Endocrinology, limiting it down to topics relating to Immunostaining and, in certain cases, Immunocytochemistry.

She most often published in these fields:

  • Transforming growth factor (44.72%)
  • Transforming growth factor beta (36.02%)
  • Internal medicine (32.92%)

What were the highlights of her more recent work (between 2007-2020)?

  • Pathology (23.60%)
  • Cancer research (18.01%)
  • Transforming growth factor (44.72%)

In recent papers she was focusing on the following fields of study:

Her primary areas of investigation include Pathology, Cancer research, Transforming growth factor, Transforming growth factor beta and Internal medicine. Within one scientific family, Kathleen C. Flanders focuses on topics pertaining to Inflammation under Pathology, and may sometimes address concerns connected to Anatomical pathology, Granulocyte, NEUTROPHIL MIGRATION and Andrology. The various areas that Kathleen C. Flanders examines in her Cancer research study include Carcinogenesis, Cancer, Metastasis, Epithelium and SMAD.

Her work in Transforming growth factor tackles topics such as Wound healing which are related to areas like Tenascin C, Fibronectin and Tenascin. Her Transforming growth factor beta study combines topics from a wide range of disciplines, such as Molecular biology, Cholestasis, Mammary gland and Halofuginone. Her Internal medicine study incorporates themes from Endocrinology, Affect and Oncology.

Between 2007 and 2020, her most popular works were:

  • Progressive Tumor Formation in Mice with Conditional Deletion of TGF-β Signaling in Head and Neck Epithelia Is Associated with Activation of the PI3K/Akt Pathway (75 citations)
  • Targeted disruption of Smad3 confers resistance to the development of dimethylnitrosamine-induced hepatic fibrosis in mice. (75 citations)
  • Transient Tumor-Fibroblast Interactions Increase Tumor Cell Malignancy by a TGF-β Mediated Mechanism in a Mouse Xenograft Model of Breast Cancer (69 citations)

In her most recent research, the most cited papers focused on:

  • Gene
  • Cancer
  • Enzyme

Pathology, Fibrosis, Transforming growth factor, Cancer research and Transforming growth factor beta are her primary areas of study. Her work in the fields of Immunohistochemistry overlaps with other areas such as Head and neck squamous-cell carcinoma. Her Fibrosis study integrates concerns from other disciplines, such as Extracellular matrix, Genetically modified mouse and Endocrinology.

Her study in Transforming growth factor is interdisciplinary in nature, drawing from both Inflammation, Wound healing, Carcinogenesis, Knockout mouse and Signal transduction. Her Cancer research research is multidisciplinary, relying on both Cell migration, DMBA, Conditional gene knockout, PI3K/AKT/mTOR pathway and Cell type. Her Transforming growth factor beta research includes elements of Tumor microenvironment, Metastasis, Cancer-Associated Fibroblasts and Stromal cell.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Transforming growth factor beta 1 null mutation in mice causes excessive inflammatory response and early death.

Ashok B. Kulkarni;Chang-Goo Huh;Dean Becker;Andrew Geiser.
Proceedings of the National Academy of Sciences of the United States of America (1993)

2241 Citations

Evidence that transforming growth factor-β is a hormonally regulated negative growth factor in human breast cancer cells

Cornelius Knabbe;Marc E. Lippman;Lalage M. Wakefield;Kathleen C. Flanders.
Cell (1987)

1456 Citations

Role of transforming growth factor-beta in the development of the mouse embryo.

U. I. Heine;E. F. Munoz;K. C. Flanders;L. R. Ellingsworth.
Journal of Cell Biology (1987)

1051 Citations

Latent transforming growth factor-beta from human platelets. A high molecular weight complex containing precursor sequences.

L M Wakefield;D M Smith;K C Flanders;M B Sporn.
Journal of Biological Chemistry (1988)

762 Citations

Transforming growth factor-beta. Major role in regulation of extracellular matrix.

Anita B. Roberts;Ursula I. Heine;Kathleen C. Flanders;Michael B. Sporn.
Annals of the New York Academy of Sciences (1990)

759 Citations

Smad3 as a mediator of the fibrotic response

Kathleen C Flanders.
International Journal of Experimental Pathology (2004)

736 Citations

Osteoblasts synthesize and respond to transforming growth factor-type beta (TGF-beta) in vitro.

P G Robey;M F Young;K C Flanders;N S Roche.
Journal of Cell Biology (1987)

707 Citations

Transforming growth factor beta 1 positively regulates its own expression in normal and transformed cells.

E Van Obberghen-Schilling;N S Roche;K C Flanders;M B Sporn.
Journal of Biological Chemistry (1988)

674 Citations

Immunodetection and quantitation of the two forms of transforming growth factor‐beta (TGF‐β1 and TGF‐β2) secreted by cells in culture

David Danielpour;Linda L. Dart;Kathleen C. Flanders;Anita B. Roberts.
Journal of Cellular Physiology (1989)

662 Citations

Expression of transforming growth factor-beta 1 in specific cells and tissues of adult and neonatal mice.

N L Thompson;K C Flanders;J M Smith;L R Ellingsworth.
Journal of Cell Biology (1989)

600 Citations

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