The scientist’s investigation covers issues in Cell biology, Transforming growth factor beta, Carcinogenesis, Transforming growth factor, beta 3 and Transforming growth factor. Her Cell biology research is multidisciplinary, incorporating perspectives in Internal medicine and Endocrinology. In her study, Kinase, Molecular biology and Kinase activity is strongly linked to Cancer cell, which falls under the umbrella field of Transforming growth factor beta.
The Carcinogenesis study combines topics in areas such as Tumor progression, Cancer research and Carcinoma. Her Transforming growth factor, beta 3 study combines topics from a wide range of disciplines, such as TGF beta signaling pathway, TGF beta receptor 2 and TGF beta 1. Rosemary J. Akhurst has included themes like Vasculogenesis and Immunology in her TGF beta signaling pathway study.
Her primary areas of investigation include Transforming growth factor, Cancer research, Cell biology, Transforming growth factor beta and Genetics. Her research integrates issues of DNA damage, Receptor, Autocrine signalling, In situ hybridization and ITGB8 in her study of Transforming growth factor. Her work carried out in the field of Cancer research brings together such families of science as Carcinogenesis, Cancer, Epithelial–mesenchymal transition and Signal transduction.
Her studies in Cell biology integrate themes in fields like Endothelial stem cell, Transforming growth factor, beta 3, Internal medicine and Endocrinology. The various areas that Rosemary J. Akhurst examines in her Transforming growth factor beta study include Immunology, TGF beta signaling pathway, Molecular biology, Knockout mouse and Metastasis. Her Immunology research incorporates themes from Yolk sac and Haematopoiesis.
Cancer research, Transforming growth factor, Cancer, Cell biology and Signal transduction are her primary areas of study. Her Cancer research study integrates concerns from other disciplines, such as Genetic variation and Immunotherapy. Her research in Transforming growth factor intersects with topics in Stromal cell and ITGB8.
Her Cancer study also includes fields such as
The scientist’s investigation covers issues in Transforming growth factor, Cancer research, Cancer, Signal transduction and Immunotherapy. Her Transforming growth factor research focuses on Transforming growth factor beta in particular. Her study in Cancer research is interdisciplinary in nature, drawing from both Cancer stem cell, Stem cell, Blockade, Transmembrane protein and PI3K/AKT/mTOR pathway.
Her Cancer research incorporates elements of Fibrosis, Receptor and Cell type. Her Signal transduction research is multidisciplinary, relying on both SUPERFAMILY, Tgfβ superfamily and Bioinformatics. Her biological study spans a wide range of topics, including Epithelial–mesenchymal transition and T cell.
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TGF-beta signaling in tumor suppression and cancer progression.
Rik Derynck;Rosemary J. Akhurst;Allan Balmain.
Nature Genetics (2001)
Targeting the TGFβ signalling pathway in disease.
Rosemary J. Akhurst;Akiko Hata.
Nature Reviews Drug Discovery (2012)
Defective haematopoiesis and vasculogenesis in transforming growth factor-beta 1 knock out mice
Marion C. Dickson;Julie S. Martin;Frances M. Cousins;Ashok B. Kulkarni.
Development (1995)
TGF-β signaling in cancer – a double-edged sword
Rosemary J Akhurst;Rik Derynck.
Trends in Cell Biology (2001)
TGFβ1 Inhibits the Formation of Benign Skin Tumors, but Enhances Progression to Invasive Spindle Carcinomas in Transgenic Mice
Wei Cui;Deborah J Fowlis;Sheila Bryson;Elizabeth Duffie.
Cell (1996)
Embryonic gene expression patterns of TGF beta 1, beta 2 and beta 3 suggest different developmental functions in vivo.
F.A. Millan;F. Denhez;P. Kondaiah;R.J. Akhurst.
Development (1991)
Metastasis is driven by sequential elevation of H-ras and Smad2 levels.
Martin Oft;Rosemary J. Akhurst;Rosemary J. Akhurst;Allan Balmain;Allan Balmain.
Nature Cell Biology (2002)
Differentiation plasticity regulated by TGF-β family proteins in development and disease
Rik Derynck;Rosemary J. Akhurst.
Nature Cell Biology (2007)
Embryonic expression pattern of TGF beta type-1 RNA suggests both paracrine and autocrine mechanisms of action.
S.A. Lehnert;R.J. Akhurst.
Development (1988)
Localized production of TGF-β mRNA in tumour promoter-stimulated mouse epidermis
R J Akhurst;F Fee;A Balmain.
Nature (1988)
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