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D-Index & Metrics

Biology and Biochemistry

D-Index
65
Citations
16291
World Ranking
9094
National Ranking
4040

Overview

Christopher J. Kemp is affiliated with the Fred Hutchinson Cancer Research Center in the United States. Their research spans several fields including medicine and biochemistry, genetics, and molecular biology, with significant contributions in neurology, molecular biology, oncology, pulmonary and respiratory medicine, and cancer research.

The scientist's recent published papers cover a range of topics and venues:

  • "An expanded universe of cancer targets" (2021) published in Cell
  • "Developmental exposure to the organochlorine pesticide dieldrin causes male-specific exacerbation of α-synuclein-preformed fibril-induced toxicity and motor deficits" (2020) published in Neurobiology of Disease
  • "Striatal Afferent BDNF Is Disrupted by Synucleinopathy and Partially Restored by STN DBS" (2021) published in Journal of Neuroscience
  • "BET, SRC, and BCL2 family inhibitors are synergistic drug combinations with PARP inhibitors in ovarian cancer" (2020) published in EBioMedicine
  • "Targeting BET Proteins BRD2 and BRD3 in Combination with PI3K-AKT Inhibition as a Therapeutic Strategy for Ovarian Clear Cell Carcinoma" (2021) published in Molecular Cancer Therapeutics

Kemp has frequently collaborated with several coauthors including Caryl E. Sortwell, Carla Grandori, Joseph R. Patterson, Anna C. Stoll, and Kelvin C. Luk.

Their main topics of research include:

  • Parkinson's Disease Mechanisms and Treatments
  • Neurological disorders and treatments
  • Alzheimer's disease research and treatments
  • Cancer Genomics and Diagnostics
  • Botulinum Toxin and Related Neurological Disorders
  • Ovarian cancer diagnosis and treatment
  • Bioinformatics and Genomic Networks

Frequent publication venues where Kemp's work appears are:

  • Cancer Research
  • Journal of Clinical Oncology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Neurobiology of Disease
  • npj Parkinson's Disease

Their research represents a cross-disciplinary approach bridging neurological diseases and cancer biology, particularly focusing on molecular pathways and therapeutic strategies.

Best Publications

  • The murine gene p27Kip1 is haplo-insufficient for tumour suppression

    Matthew L. Fero;Erin Randel;Kay E. Gurley;James M. Roberts;James M. Roberts

  • Personalized In Vitro and In Vivo Cancer Models to Guide Precision Medicine

    Chantal Pauli;Chantal Pauli;Chantal Pauli;Benjamin D Hopkins;Davide Prandi;Reid Shaw

  • Doxorubicin, DNA torsion, and chromatin dynamics.

    Fan Yang;Sheila S. Teves;Christopher J. Kemp;Steven Henikoff;Steven Henikoff

  • The role of p53 in spontaneous and radiation-induced apoptosis in the gastrointestinal tract of normal and p53-deficient mice.

    Anita J. Merritt;Christopher S. Potten;Christopher J. Kemp;John A. Hickman

  • Reduction of p53 gene dosage does not increase initiation or promotion but enhances malignant progression of chemically induced skin tumors.

    Christopher J. Kemp;Lawrence A. Donehower;Allan Bradley;Allan Balmain

  • p53 -deficient mice are extremely susceptible to radiation-induced tumorigenesis

    Christopher J. Kemp;Tom Wheldon;Allan Balmain

  • p27(Kip1): regulation and function of a haploinsufficient tumor suppressor and its misregulation in cancer.

    Jeannette Philipp-Staheli;Shannon R. Payne;Christopher J. Kemp

  • A targeted proteomics-based pipeline for verification of biomarkers in plasma

    Jeffrey R Whiteaker;Chenwei Lin;Jacob Kennedy;Liming Hou

  • The mutational landscapes of genetic and chemical models of Kras -driven lung cancer

    Peter M. K. Westcott;Kyle D. Halliwill;Minh D. To;Mamunur Rashid

  • A pathway in quiescent cells that controls p27Kip1 stability, subcellular localization, and tumor suppression

    Arnaud Besson;Mark Gurian-West;Xueyan Chen;Karen S. Kelly-Spratt

  • High Throughput Quantitative Analysis of Serum Proteins Using Glycopeptide Capture and Liquid Chromatography Mass Spectrometry

    Hui Zhang;Eugene C. Yi;Xiao Jun Li;Parag Mallick

  • Tumor suppressor genetics

    Shannon R. Payne;Christopher J. Kemp

  • A Software Suite for the Generation and Comparison of Peptide Arrays from Sets of Data Collected by Liquid Chromatography-Mass Spectrometry

    Xiao Jun Li;Eugene C. Yi;Christopher J. Kemp;Hui Zhang

  • Integrated pipeline for mass spectrometry-based discovery and confirmation of biomarkers demonstrated in a mouse model of breast cancer

    Jeffrey R. Whiteaker;Heidi Zhang;Lei Zhao;Pei Wang

  • TRAIL-R deficiency in mice enhances lymph node metastasis without affecting primary tumor development

    Anne Grosse-Wilde;Oksana Voloshanenko;S. Lawrence Bailey;Gary M. Longton

  • Consumption of a high-fat diet induces central insulin resistance independent of adiposity.

    Deborah J. Clegg;Koro Gotoh;Christopher Kemp;Matthew D. Wortman

  • The crystal structure of palmitoyl protein thioesterase 1 and the molecular basis of infantile neuronal ceroid lipofuscinosis.

    John J. Bellizzi;Joanne Widom;Christopher Kemp;Jui Yun Lu

  • Loss of heterozygosity and mutational alterations of the p53 gene in skin tumours of interspecific hybrid mice.

    Burns Pa;Kemp Cj;Gannon Jv;Lane Dp

  • Multistep skin cancer in mice as a model to study the evolution of cancer cells

    Christopher J Kemp

  • A Software Suite for the Generation and Comparison of Peptide Arrays from Sets of Data Collected by Liquid

    Xiao-jun Li;Eugene C. Yi;Christopher J. Kemp;Hui Zhang

Frequent Co-Authors

Allan Balmain
Allan Balmain University of California, San Francisco
Steven Henikoff
Steven Henikoff Fred Hutchinson Cancer Research Center
Hui Zhang
Hui Zhang Johns Hopkins University
Samir M. Hanash
Samir M. Hanash The University of Texas MD Anderson Cancer Center
Eugene C. Yi
Eugene C. Yi Seoul National University
Stephen C. Benoit
Stephen C. Benoit University of Cincinnati
Amanda G. Paulovich
Amanda G. Paulovich Fred Hutchinson Cancer Research Center
Rosemary J. Akhurst
Rosemary J. Akhurst University of California, San Francisco
Pei Wang
Pei Wang Icahn School of Medicine at Mount Sinai

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