Jian-Hua Mao spends much of his time researching Cancer research, Genetics, Cancer, Gene and Carcinogenesis. His Cancer research research includes elements of Tumor suppressor gene, Molecular biology, PI3K/AKT/mTOR pathway and Immunology. His work in the fields of DNA, Human genome, Comparative genomic hybridization and Genome overlaps with other areas such as Mus spretus.
His Cancer research includes themes of Chromosome instability, Epigenetics, Kinetochore and Bioinformatics. His Carcinogenesis research is multidisciplinary, incorporating elements of Stem cell, Ubiquitin ligase, FBXW7 Gene, Loss of heterozygosity and Genetic screen. His studies examine the connections between Ubiquitin ligase and genetics, as well as such issues in Epithelial–mesenchymal transition, with regards to Gene silencing and Breast cancer.
Jian-Hua Mao focuses on Cancer research, Cancer, Genetics, Carcinogenesis and Gene. Jian-Hua Mao interconnects Cell growth, Molecular biology, Breast cancer, Tumor suppressor gene and Lung cancer in the investigation of issues within Cancer research. Jian-Hua Mao has included themes like Cancer cell and Regulation of gene expression in his Molecular biology study.
His work deals with themes such as Oncology and Bioinformatics, which intersect with Cancer. In the subject of general Genetics, his work in Allele, Quantitative trait locus, Genetic linkage and Genetic variation is often linked to Mus spretus, thereby combining diverse domains of study. His Carcinogenesis study also includes fields such as
Jian-Hua Mao mainly focuses on Microbiome, Cancer research, Internal medicine, Cell biology and Carcinogenesis. His biological study spans a wide range of topics, including Gene knockdown, CUL4A, Immune system, Metastasis and Tumor progression. His Internal medicine study combines topics from a wide range of disciplines, such as Breastfeeding, Plasma protein binding and Oncology.
His Cell biology study integrates concerns from other disciplines, such as Platelet, Integrin, Fibrinogen and Metabolome. His Carcinogenesis research incorporates elements of Cytotoxic T cell, Immunosuppression, CD8 and Carcinogen. As a part of the same scientific study, Jian-Hua Mao usually deals with the Gene expression, concentrating on Immunohistochemistry and frequently concerns with Cancer.
Jian-Hua Mao mostly deals with Microbiome, Cancer research, Gene, Metastasis and Metabolomics. His studies deal with areas such as Metabolome, Feces and Resveratrol, Pharmacology as well as Microbiome. His work often combines Cancer research and Kinetics studies.
Gene is closely attributed to Immunohistochemistry in his research. His Metastasis study combines topics in areas such as Downregulation and upregulation, Oncogene, CUL4A, Lung cancer and Gene silencing. His research integrates issues of Cancer, Tissue microarray, Laboratory mouse and Candidate gene in his study of Gene expression.
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Dissection of mechanisms of Chinese medicinal formula Realgar-Indigo naturalis as an effective treatment for promyelocytic leukemia
Lan Wang;Guang Biao Zhou;Guang Biao Zhou;Ping Liu;Jun Hong Song.
Proceedings of the National Academy of Sciences of the United States of America (2008)
FBXW7 targets mTOR for degradation and cooperates with PTEN in tumor suppression.
Jian-Hua Mao;Il-Jin Kim;Di Wu;Joan Climent.
Identification of Stk6/STK15 as a candidate low-penetrance tumor-susceptibility gene in mouse and human
Amanda Ewart-Toland;Paraskevi Briassouli;John P de Koning;John P de Koning;Jian-Hua Mao.
Nature Genetics (2003)
RNA-seq analysis of prostate cancer in the Chinese population identifies recurrent gene fusions, cancer-associated long noncoding RNAs and aberrant alternative splicings
Shancheng Ren;Zhiyu Peng;Jian-Hua Mao;Yongwei Yu.
Cell Research (2012)
Fbxw7 / Cdc4 is a p53-dependent, haploinsufficient tumour suppressor gene
Jian-Hua Mao;Jesus Perez-losada;Di Wu;Reyno DelRosario.
Amplification of PVT1 Contributes to the Pathophysiology of Ovarian and Breast Cancer
Yinghui Guan;Wen Lin Kuo;Jackie L. Stilwell;Hirokuni Takano.
Clinical Cancer Research (2007)
A Mouse Skin Multistage Carcinogenesis Model Reflects the Aberrant DNA Methylation Patterns of Human Tumors
Mario F. Fraga;Michel Herranz;Jesús Espada;Esteban Ballestar.
Cancer Research (2004)
Dissociation of Epithelial and Neuroendocrine Carcinoma Lineages in the Transgenic Adenocarcinoma of Mouse Prostate Model of Prostate Cancer
Teresa Chiaverotti;Suzana S. Couto;Annemarie Donjacour;Jian-Hua Mao.
American Journal of Pathology (2008)
Genome-wide detection of chromosomal imbalances in tumors using BAC microarrays.
Wei-Wen Cai;Jian-Hua Mao;Chi-Wen Chow;Shamsha Damani.
Nature Biotechnology (2002)
A 12-Gene Set Predicts Survival Benefits from Adjuvant Chemotherapy in Non-Small-Cell Lung Cancer Patients
Hao Tang;Guanghua Xiao;Carmen Behrens;Joan Schiller.
Clinical Cancer Research (2013)
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