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Genetics

D-Index
69
Citations
33641
World Ranking
2311
National Ranking
1043

Overview

Gary H. Karpen is affiliated with the University of California, Berkeley in the United States. Their research primarily falls within the field of Biochemistry, Genetics and Molecular Biology, with a focused specialization in Molecular Biology.

The scientist's work covers several subfields, including Plant Science, Physiology, Pulmonary and Respiratory Medicine, and Radiology, Nuclear Medicine and Imaging. Their research interests also extend across multiple key topics such as Genomics and Chromatin Dynamics, RNA Research and Splicing, Chromosomal and Genetic Variations, RNA modifications and cancer, CRISPR and Genetic Engineering, RNA and protein synthesis mechanisms, and the effects of Spaceflight on biology.

Among Gary H. Karpen's recent papers are:

  • Complete genomic and epigenetic maps of human centromeres, 2022, Science
  • HP1-driven phase separation recapitulates the thermodynamics and kinetics of heterochromatin condensate formation, 2023, Proceedings of the National Academy of Sciences
  • Innovation of heterochromatin functions drives rapid evolution of essential ZAD-ZNF genes in Drosophila, 2020, eLife
  • Pericentromeric heterochromatin is hierarchically organized and spatially contacts H3K9me2 islands in euchromatin, 2020, PLoS Genetics
  • Mouse genomic associations with in vitro sensitivity to simulated space radiation, 2022, Life Sciences in Space Research

Frequent co-authors in their research collaborations include Lucy D. Brennan, Serafin U. Colmenares, S. A. Safran, Nicolas Altemose, and Sasha A. Langley.

The scientist has published extensively in various venues. Most frequently, their publications have appeared in bioRxiv (Cold Spring Harbor Laboratory), Biophysical Journal, UNC Libraries, Nucleic Acids Research, and Science.

Best Publications

  • The genome sequence of Drosophila melanogaster

    M. D. Adams;S. E. Celniker;R. A. Holt;C. A. Evans

  • Evolution of genes and genomes on the Drosophila phylogeny.

    Andrew G. Clark;Michael B. Eisen;Michael B. Eisen;Douglas R. Smith;Casey M. Bergman

  • Phase Separation Drives Heterochromatin Domain Formation

    Amy R. Strom;Alexander V. Emelyanov;Mustafa R. Mir;Dmitry V. Fyodorov

  • Identification of Functional Elements and Regulatory Circuits by Drosophila modENCODE

    Sushmita Roy;Jason Ernst;Peter V. Kharchenko;Pouya Kheradpour

  • Comprehensive analysis of the chromatin landscape in Drosophila melanogaster

    Peter V. Kharchenko;Artyom A. Alekseyenko;Artyom A. Alekseyenko;Yuri B. Schwartz;Aki Minoda

  • Unlocking the Secrets of the Genome

    Susan E. Celniker;Laura A. L. Dillon;Mark B. Gerstein;Kristin C. Gunsalus

  • Epigenetic regulation of centromeric chromatin: old dogs, new tricks?

    Robin C. Allshire;Gary H. Karpen

  • Conserved Organization of Centromeric Chromatin in Flies and Humans

    Michael D. Blower;Beth A. Sullivan;Gary H. Karpen

  • Centromeric chromatin exhibits a histone modification pattern that is distinct from both euchromatin and heterochromatin

    Beth A Sullivan;Gary H Karpen;Gary H Karpen;Gary H Karpen

  • The case for epigenetic effects on centromere identity and function

    Gary H. Karpen;Robin C. Allshire

  • Double-Strand Breaks in Heterochromatin Move Outside of a Dynamic HP1a Domain to Complete Recombinational Repair

    Irene Chiolo;Aki Minoda;Serafin U. Colmenares;Aris Polyzos

  • Analysis of subtelomeric heterochromatin in the Drosophila minichromosome Dp1187 by single P element insertional mutagenesis.

    G H Karpen;A C Spradling

  • An assessment of histone-modification antibody quality

    Thea A. Egelhofer;Aki Minoda;Aki Minoda;Sarit Klugman;Sarit Klugman;Kyungjoon Lee

  • H3K9 methylation and RNA interference regulate nucleolar organization and repeated DNA stability

    Jamy C. Peng;Gary H. Karpen;Gary H. Karpen

  • The Release 6 reference sequence of the Drosophila melanogaster genome

    Roger A. Hoskins;Joseph W. Carlson;Kenneth H. Wan;Soo Park

  • The role of Drosophila CID in kinetochore formation, cell-cycle progression and heterochromatin interactions

    Michael D. Blower;Gary H. Karpen

  • Comparative analysis of metazoan chromatin organization

    Joshua Wing Kei Ho;Joshua Wing Kei Ho;Youngsook L. Jung;Tao Liu;Tao Liu;Burak Han Alver

  • Heterochromatin: Guardian of the Genome

    Aniek Janssen;Serafin U Colmenares;Gary H Karpen

  • Mislocalization of the Drosophila centromere-specific histone CID promotes formation of functional ectopic kinetochores

    Patrick Heun;Sylvia Erhardt;Michael D. Blower;Samara Weiss

  • Preferential transposition of Drosophila P elements to nearby chromosomal sites.

    J Tower;G H Karpen;N Craig;A C Spradling

Frequent Co-Authors

Peter J. Park
Peter J. Park Harvard University
Mitzi I. Kuroda
Mitzi I. Kuroda Brigham and Women's Hospital
Susan E. Celniker
Susan E. Celniker Lawrence Berkeley National Laboratory
Michael Y. Tolstorukov
Michael Y. Tolstorukov Harvard University
Peter V. Kharchenko
Peter V. Kharchenko Harvard University
Sarah C. R. Elgin
Sarah C. R. Elgin Washington University in St. Louis
Roger A. Hoskins
Roger A. Hoskins Lawrence Berkeley National Laboratory
Jian-Hua Mao
Jian-Hua Mao Lawrence Berkeley National Laboratory
Allan C. Spradling
Allan C. Spradling Carnegie Institution for Science

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