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Genetics

D-Index
106
Citations
59260
World Ranking
591
National Ranking
296

Research.com Recognitions

  • 2008 - Gruber Prize in Genetics
  • 2003 - Edwin Grant Conklin Medal, Society for Developmental Biology
  • 1992 - Fellow of the American Association for the Advancement of Science (AAAS)
  • 1991 - Fellow of the American Academy of Arts and Sciences
  • 1989 - Genetics Society of America Medal
  • 1989 - Member of the National Academy of Sciences

Overview

Allan C. Spradling is affiliated with the Carnegie Institution for Science in the United States. Their research primarily focuses on the field of Biochemistry, Genetics, and Molecular Biology, with significant contributions to Molecular Biology, Insect Science, Public Health, Environmental and Occupational Health, Genetics, and Immunology.

The scientist's work covers several main topics, including:

  • Reproductive Biology and Fertility
  • Insect symbiosis and bacterial influences
  • Invertebrate Immune Response Mechanisms
  • Genomics and Chromatin Dynamics
  • Developmental Biology and Gene Regulation
  • Neurobiology and Insect Physiology Research
  • Animal Genetics and Reproduction

Spradling has published extensively, with frequent appearances in several journals and publication venues. These include:

  • bioRxiv (Cold Spring Harbor Laboratory), with 13 publications
  • eLife, with 7 publications
  • Proceedings of the National Academy of Sciences, with 5 publications
  • BMC Genomics, with 2 publications
  • Science, with 2 publications

Notable recent papers authored or coauthored by Spradling include:

  • "Two distinct pathways of pregranulosa cell differentiation support follicle formation in the mouse ovary," 2020, Proceedings of the National Academy of Sciences
  • "Mouse oocytes develop in cysts with the help of nurse cells," 2022, Cell
  • "Conservation of oocyte development in germline cysts from Drosophila to mouse," 2022, eLife
  • "A symbiotic physical niche in Drosophila melanogaster regulates stable association of a multi-species gut microbiota," 2023, Nature Communications
  • "An abundant quiescent stem cell population in Drosophila Malpighian tubules protects principal cells from kidney stones," 2020, eLife

Frequent collaborators in Spradling's research network include:

  • Haolong Zhu
  • John Urban
  • Wanbao Niu
  • Chenhui Wang
  • Steven Z. DeLuca

Throughout their career, Spradling has received several awards recognizing their contributions to science, such as:

  • Gruber Prize in Genetics (2008)
  • Edwin Grant Conklin Medal, Society for Developmental Biology (2003)
  • Fellow of the American Association for the Advancement of Science (AAAS) (1992)
  • Fellow of the American Academy of Arts and Sciences (1991)
  • Member of the National Academy of Sciences (1989)
  • Genetics Society of America Medal (1989)

Best Publications

  • The genome sequence of Drosophila melanogaster

    M. D. Adams;S. E. Celniker;R. A. Holt;C. A. Evans

  • Genetic Transformation of Drosophila with Transposable Element Vectors

    Gerald M. Rubin;Allan C. Spradling

  • Stem Cells and Niches: Mechanisms That Promote Stem Cell Maintenance throughout Life

    Sean J. Morrison;Allan C. Spradling

  • Transposition of cloned P elements into Drosophila germ line chromosomes

    Allan C. Spradling;Gerald M. Rubin

  • Stem cells find their niche

    Allan Spradling;Daniela Drummond-Barbosa;Toshie Kai

  • Developmental genetics of oogenesis

    A. Spradling

  • The adult Drosophila posterior midgut is maintained by pluripotent stem cells

    Benjamin Ohlstein;Allan Spradling

  • The BDGP gene disruption project: single transposon insertions associated with 40% of Drosophila genes.

    Hugo J. Bellen;Robert W. Levis;Guochun Liao;Yuchun He

  • The Berkeley Drosophila Genome Project gene disruption project: Single P-element insertions mutating 25% of vital Drosophila genes.

    A C Spradling;D Stern;A Beaton;E J Rhem

  • A Niche Maintaining Germ Line Stem Cells in the Drosophila Ovary

    Ting Xie;Allan C. Spradling

  • A novel group of pumilio mutations affects the asymmetric division of germline stem cells in the Drosophila ovary

    Haifan Lin;Allan C. Spradling

  • Mouse ovarian germ cell cysts undergo programmed breakdown to form primordial follicles.

    Melissa E. Pepling;Allan C. Spradling

  • decapentaplegic is essential for the maintenance and division of germline stem cells in the Drosophila ovary.

    Ting Xie;Allan C Spradling

  • Insertional mutagenesis of the Drosophila genome with single P elements

    Lynn Cooley;Richard Kelley;Allan Spradling

  • MiMIC: a highly versatile transposon insertion resource for engineering Drosophila melanogaster genes.

    Koen J T Venken;Karen L Schulze;Nele A Haelterman;Hongling Pan

  • Identification and behavior of epithelial stem cells in the Drosophila ovary

    J. Margolis;A. Spradling

  • Multipotent Drosophila Intestinal Stem Cells Specify Daughter Cell Fates by Differential Notch Signaling

    Benjamin Ohlstein;Allan Spradling

  • Stem cells and their progeny respond to nutritional changes during Drosophila oogenesis.

    Daniela Drummond-Barbosa;Allan C. Spradling

  • The Carnegie Protein Trap Library: A Versatile Tool for Drosophila Developmental Studies

    Michael Buszczak;Shelley Paterno;Daniel Lighthouse;Julia Bachman

  • The Berkeley Drosophila Genome Project gene disruption project: Single P-element insertions mutating 25% of vital Drosophila genes.

    N Mozden;Hari S. Misra;E J Rhem;Daniel A. Beaton

Frequent Co-Authors

Gerald M. Rubin
Gerald M. Rubin Howard Hughes Medical Institute
Hugo J. Bellen
Hugo J. Bellen Baylor College of Medicine
Roger A. Hoskins
Roger A. Hoskins Lawrence Berkeley National Laboratory
Norbert Perrimon
Norbert Perrimon Harvard University
Stephanie E. Mohr
Stephanie E. Mohr Harvard University
Yanhui Hu
Yanhui Hu Harvard University
Gary H. Karpen
Gary H. Karpen University of California, Berkeley
Michael Ashburner
Michael Ashburner University of Cambridge
Suzanna E. Lewis
Suzanna E. Lewis Lawrence Berkeley National Laboratory
Susan E. Celniker
Susan E. Celniker Lawrence Berkeley National Laboratory

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