World's Best Scientists 2026 revealed!

D-Index & Metrics

Molecular Biology

D-Index
70
Citations
24726
World Ranking
1400
National Ranking
710

Research.com Recognitions

  • 2012 - Fellow of the American Association for the Advancement of Science (AAAS)
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)

Overview

Bruce A. Edgar is affiliated with the Huntsman Cancer Institute in the United States. Their research spans multiple areas within biochemistry, genetics, molecular biology, immunology, and microbiology. The scientist's primary fields of study include biochemistry, genetics and molecular biology with 25 publications, and immunology and microbiology with 16 publications.

The subfields of study that Bruce A. Edgar has contributed to are:

  • Immunology
  • Molecular Biology
  • Cellular and Molecular Neuroscience
  • Insect Science
  • Oncology

The main research topics addressed by their work include:

  • Invertebrate Immune Response Mechanisms
  • Neurobiology and Insect Physiology Research
  • Insect symbiosis and bacterial influences
  • Aquaculture disease management and microbiota
  • Epigenetics and DNA Methylation
  • Cancer-related Molecular Pathways
  • Insect Utilization and Effects

Bruce A. Edgar has contributed to research published in several venues, with frequent publications in:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • eLife
  • Proceedings of the National Academy of Sciences
  • UNC Libraries
  • Nature

Notable recent papers authored or co-authored include:

  • Fitness trade-offs incurred by ovary-to-gut steroid signalling in Drosophila (2020, Nature)
  • Remodelling of oxygen-transporting tracheoles drives intestinal regeneration and tumorigenesis in Drosophila (2021, Nature Cell Biology)
  • Insect Gut Regeneration (2021, Cold Spring Harbor Perspectives in Biology)
  • EGFR signaling activates intestinal stem cells by promoting mitochondrial biogenesis and β-oxidation (2022, Current Biology)
  • Age-related changes in polycomb gene regulation disrupt lineage fidelity in intestinal stem cells (2021, eLife)

The scientist has collaborated frequently with several co-authors, including:

  • Marco Marchetti
  • Chenge Zhang
  • Peng Zhang
  • Mohammed Mahidur Rahman
  • Mitchell R. Lewis

Bruce A. Edgar has been recognized with several awards during their career. These include election as a Fellow of the American Association for the Advancement of Science (AAAS) in 2012 and membership in the European Molecular Biology Organization (EMBO).

Best Publications

  • Rheb is a direct target of the tuberous sclerosis tumour suppressor proteins.

    Yong Zhang;Yong Zhang;Xinsheng Gao;Leslie J. Saucedo;Binggen Ru

  • Cytokine/Jak/Stat Signaling Mediates Regeneration and Homeostasis in the Drosophila Midgut

    Huaqi Jiang;Parthive H. Patel;Alexander Kohlmaier;Marc O. Grenley

  • Endoreplication cell cycles: more for less.

    Bruce A. Edgar;Terry L. Orr-Weaver

  • Coordination of Growth and Cell Division in the Drosophila Wing

    Thomas P Neufeld;Aida Flor A de la Cruz;Laura A Johnston;Bruce A Edgar

  • Rheb promotes cell growth as a component of the insulin/TOR signalling network

    Leslie J. Saucedo;Xinsheng Gao;Dominic A. Chiarelli;Ling Li

  • Sequence-specific binding of glucocorticoid receptor to MTV DNA at sites within and upstream of the transcribed region.

    Farhang Payvar;Donald DeFranco;Gary L. Firestone;Bruce Edgar

  • Drosophila myc Regulates Cellular Growth during Development

    Laura A. Johnston;David A. Prober;Bruce A. Edgar;Robert N. Eisenman

  • Drosophila's Insulin/PI3-Kinase Pathway Coordinates Cellular Metabolism with Nutritional Conditions

    Jessica S. Britton;Wendy K. Lockwood;Ling Li;Stephen M. Cohen

  • Genetic control of cell division patterns in the Drosophila embryo

    Bruce A. Edgar;Patrick H. O'Farrell

  • The three postblastoderm cell cycles of Drosophila embryogenesis are regulated in G2 by string

    Bruce A. Edgar;Patrick H. O'Farrell

  • Environmental control of the cell cycle in Drosophila: nutrition activates mitotic and endoreplicative cells by distinct mechanisms

    Jessica S. Britton;Bruce A. Edgar

  • How flies get their size: genetics meets physiology.

    Bruce A. Edgar

  • EGFR/Ras/MAPK signaling mediates adult midgut epithelial homeostasis and regeneration in Drosophila.

    Huaqi Jiang;Marc O. Grenley;Maria Jose Bravo;Rachel Z. Blumhagen

  • Genomic binding by the Drosophila Myc, Max, Mad/Mnt transcription factor network

    Amir Orian;Bas van Steensel;Jeffrey Delrow;Harmen J. Bussemaker

  • Myc-dependent regulation of ribosomal RNA synthesis during Drosophila development.

    Savraj S. Grewal;Ling Li;Amir Orian;Robert N. Eisenman

  • Parameters controlling transcriptional activation during early drosophila development

    Bruce A. Edgar;Gerold Schubiger

  • Cell cycle control by the nucleo-cytoplasmic ratio in early Drosophila development

    Bruce A. Edgar;Caroline P. Kiehle;Gerold Schubiger

  • Filling out the Hippo pathway.

    Leslie J. Saucedo;Leslie J. Saucedo;Bruce A. Edgar

  • From cell structure to transcription: Hippo forges a new path.

    Bruce A. Edgar

  • Developmental Control of Cell Cycle Regulators: A Fly's Perspective

    Bruce A. Edgar;Christian F. Lehner

Frequent Co-Authors

Robert N. Eisenman
Robert N. Eisenman Fred Hutchinson Cancer Research Center
Christian F. Lehner
Christian F. Lehner University of Zurich
Patrick H. O'Farrell
Patrick H. O'Farrell University of California, San Francisco
Aurelio A. Teleman
Aurelio A. Teleman German Cancer Research Center
Susan M. Parkhurst
Susan M. Parkhurst Fred Hutchinson Cancer Research Center
Cornelia M. Ulrich
Cornelia M. Ulrich University of Utah
Daniel L. Segal
Daniel L. Segal University of Colorado Colorado Springs
Harmen J. Bussemaker
Harmen J. Bussemaker Columbia University
Jeffrey J. Delrow
Jeffrey J. Delrow Fred Hutchinson Cancer Research Center
Crisanto Gutierrez
Crisanto Gutierrez Spanish National Research Council

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