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D-Index & Metrics

Molecular Biology

D-Index
67
Citations
14393
World Ranking
1582
National Ranking
38

Overview

Ross D. Hannan is affiliated with the Australian National University in Australia and specializes in research primarily centered in the fields of Biochemistry, Genetics, and Molecular Biology, with additional focus on Medicine. Their work extends across various subfields including Molecular Biology, Oncology, Cancer Research, Pulmonary and Respiratory Medicine, and Hematology.

The scientist's research covers topics such as RNA modifications and cancer, RNA research and splicing, RNA and protein synthesis mechanisms, DNA repair mechanisms, genomics and chromatin dynamics, PARP inhibition in cancer therapy, and cancer-related molecular mechanisms research. This multi-faceted focus places their work at the intersection of fundamental molecular biology and applied cancer research.

Ross D. Hannan has contributed to numerous peer-reviewed publications. Notable recent papers include:

  • CX-5461 activates the DNA damage response and demonstrates therapeutic efficacy in high-grade serous ovarian cancer (2020, Nature Communications)
  • Targeting the RNA Polymerase I Transcription for Cancer Therapy Comes of Age (2020, Cells)
  • Selective Translation Complex Profiling Reveals Staged Initiation and Co-translational Assembly of Initiation Factor Complexes (2020, Molecular Cell)
  • Nuclear stabilization of p53 requires a functional nucleolar surveillance pathway (2022, Cell Reports)
  • PGRMC1 phosphorylation affects cell shape, motility, glycolysis, mitochondrial form and function, and tumor growth (2020, BMC Molecular and Cell Biology)

Frequent co-authors associated with Ross D. Hannan include Katherine M. Hannan, Nadine Hein, Rita Ferreira, Richard B. Pearson, and Perlita Poh. These collaborations span multiple studies highlighting a networked research approach.

The scientist's work has been published repeatedly in prominent venues such as bioRxiv (Cold Spring Harbor Laboratory), Cancer Research, Molecular Cancer Therapeutics, Research Square, and Biomedicines, demonstrating consistent contributions to journals focused on cancer and molecular biology.

Best Publications

  • mTOR-dependent regulation of ribosomal gene transcription requires S6K1 and is mediated by phosphorylation of the carboxy-terminal activation domain of the nucleolar transcription factor UBF.

    Katherine M. Hannan;Yves Brandenburger;Anna Jenkins;Kerith Sharkey

  • Targeting RNA Polymerase I with an Oral Small Molecule CX-5461 Inhibits Ribosomal RNA Synthesis and Solid Tumor Growth

    Denis Drygin;Amy Lin;Josh Bliesath;Caroline B. Ho

  • Inhibition of RNA polymerase I as a therapeutic strategy to promote cancer-specific activation of p53.

    Megan J Bywater;Gretchen Poortinga;Gretchen Poortinga;Elaine Sanij;Elaine Sanij;Nadine Hein

  • The renin-angiotensin system and cancer: old dog, new tricks.

    Amee J George;Walter Glen Thomas;Ross Duncan Hannan;Ross Duncan Hannan;Ross Duncan Hannan

  • ATRX interacts with H3.3 in maintaining telomere structural integrity in pluripotent embryonic stem cells

    Lee Wong;James Derrick Robert McGhie;Marcus L J Sim;Melissa A Anderson

  • Centromere RNA is a key component for the assembly of nucleoproteins at the nucleolus and centromere.

    Lee H. Wong;Kate H. Brettingham-Moore;Lyn Chan;Julie M. Quach

  • Coordinate regulation of ribosome biogenesis and function by the ribosomal protein S6 kinase, a key mediator of mTOR function.

    Katarzyna Jastrzebski;Katherine M. Hannan;Elissaveta B. Tchoubrieva;Ross D. Hannan

  • An Immediate Response of Ribosomal Transcription to Growth Factor Stimulation in Mammals Is Mediated by ERK Phosphorylation of UBF

    Victor Y Stefanovsky;Guillaume Pelletier;Ross Hannan;Thérèse Gagnon-Kugler

  • Direct Actions of Urotensin II on the Heart: Implications for Cardiac Fibrosis and Hypertrophy

    Alex Tzanidis;Ross D Hannan;Walter G Thomas;Done Onan

  • AKT induces senescence in human cells via mTORC1 and p53 in the absence of DNA damage: implications for targeting mTOR during malignancy

    Megan Astle;Katherine Hannan;Puiyee Ng;Rachel Lee

  • The nucleolus: an emerging target for cancer therapy

    Nadine Hein;Katherine M Hannan;Katherine M Hannan;Amee J George;Amee J George;Amee J George;Elaine Sanij;Elaine Sanij

  • Targeting the nucleolus for cancer intervention

    Jaclyn E Quin;Jaclyn E Quin;Jennifer R Devlin;Jennifer R Devlin;Donald Cameron;Katherine M Hannan;Katherine M Hannan

  • UBF levels determine the number of active ribosomal RNA genes in mammals.

    Elaine Sanij;Gretchen Poortinga;Kerith Sharkey;Sandy Hung

  • Dysregulation of the basal RNA polymerase transcription apparatus in cancer

    Megan Bywater;Richard Bruce Pearson;Grant A McArthur;Ross Duncan Hannan

  • Adenoviral-Directed Expression of the Type 1A Angiotensin Receptor Promotes Cardiomyocyte Hypertrophy via Transactivation of the Epidermal Growth Factor Receptor

    Walter G. Thomas;Yves Brandenburger;Dominic J. Autelitano;Thao Pham

  • AKT promotes rRNA synthesis and cooperates with c-MYC to stimulate ribosome biogenesis in cancer.

    Joanna C. Chan;Katherine M. Hannan;Kim Riddell;Pui Yee Ng

  • MAD1 and c-MYC regulate UBF and rDNA transcription during granulocyte differentiation

    Gretchen Poortinga;Katherine M Hannan;Hayley Snelling;Carl R Walkley;Carl R Walkley

  • Cardiac hypertrophy: A matter of translation

    RD Hannan;A Jenkins;AK Jenkins;Y Brandenburger

  • A Novel Mouse Model of Atherosclerotic Plaque Instability for Drug Testing and Mechanistic/Therapeutic Discoveries Using Gene and microRNA Expression Profiling

    Yung-Chih Chen;Anh Viet Bui;Jeannine Diesch;Richard Manasseh

  • Transcription by RNA polymerase I.

    Hannan Km;Hannan Rd;Rothblum Li

Frequent Co-Authors

Richard B. Pearson
Richard B. Pearson Peter MacCallum Cancer Centre
Grant A. McArthur
Grant A. McArthur Peter MacCallum Cancer Centre
Carleen Cullinane
Carleen Cullinane Peter MacCallum Cancer Centre
Ricky W. Johnstone
Ricky W. Johnstone Peter MacCallum Cancer Centre
Walter G. Thomas
Walter G. Thomas University of Queensland
Lawrence I. Rothblum
Lawrence I. Rothblum University of Oklahoma
Henry Krum
Henry Krum Monash University
Clare L. Scott
Clare L. Scott Walter and Eliza Hall Institute of Medical Research
Antony W. Braithwaite
Antony W. Braithwaite University of Otago
Scott W. Lowe
Scott W. Lowe Memorial Sloan Kettering Cancer Center

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