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Wolfgang Wintermeyer

Wolfgang Wintermeyer

D-Index & Metrics

Biology and Biochemistry

D-Index
70
Citations
15775
World Ranking
7086
National Ranking
517

Overview

Wolfgang Wintermeyer is affiliated with the Max Planck Society in Germany. Their research revolves around biochemistry, genetics, and molecular biology, with a significant focus on molecular biology and genetics as subfields.

The main topics explored by Wintermeyer include:

  • RNA and protein synthesis mechanisms
  • Bacterial genetics and biotechnology
  • Bacteriophages and microbial interactions
  • Peptidase inhibition and analysis
  • Signaling pathways in disease
  • RNA modifications and cancer
  • Radiopharmaceutical chemistry and applications

Wintermeyer's recent publications cover various aspects of protein biogenesis and bacterial membrane proteins. Notable papers include:

  • "Co-translational insertion and topogenesis of bacterial membrane proteins monitored in real time", 2020, The EMBO Journal
  • "Lateral gate dynamics of the bacterial translocon during cotranslational membrane protein insertion", 2021, Proceedings of the National Academy of Sciences
  • "Kinetic control of nascent protein biogenesis by peptide deformylase", 2021, Scientific Reports
  • "Cotranslational Biogenesis of Membrane Proteins in Bacteria", 2022, Frontiers in Molecular Biosciences
  • "Deformylation of nascent peptide chains on the ribosome", 2023, Methods in enzymology on CD-ROM/Methods in enzymology

Frequent collaborators in Wintermeyer's research include Evan Mercier, Marina V. Rodnina, Xiaolin Wang, Manisankar Maiti, and Lena A. K. Bögeholz. This collaborative work is often published in venues such as Biophysical Journal, Faculty Opinions - Post-Publication Peer Review of the Biomedical Literature, The EMBO Journal, Proceedings of the National Academy of Sciences, and Scientific Reports.

Best Publications

  • Hydrolysis of GTP by elongation factor G drives tRNA movement on the ribosome

    Marina V. Rodnina;Andreas Savelsbergh;Vladimir I. Katunin;Wolfgang Wintermeyer

  • Complete kinetic mechanism of elongation factor Tu-dependent binding of aminoacyl-tRNA to the A site of the E. coli ribosome.

    Tillmann Pape;Wolfgang Wintermeyer;Marina V. Rodnina

  • Ribosome dynamics and tRNA movement by time-resolved electron cryomicroscopy

    Niels Fischer;Andrey L. Konevega;Wolfgang Wintermeyer;Marina V. Rodnina

  • Visualization of elongation factor Tu on the Escherichia coli ribosome

    H. Stark;M. V. Rodnina;J. Rinke-Appel;R. Brimacombe

  • Fidelity of Aminoacyl-tRNA Selection on the Ribosome: Kinetic and Structural Mechanisms

    Marina V. Rodnina;Wolfgang Wintermeyer

  • Induced fit in initial selection and proofreading of aminoacyl‐tRNA on the ribosome

    Tillmann Pape;Wolfgang Wintermeyer;Marina Rodnina

  • The Escherichia coli SRP and SecB targeting pathways converge at the translocon

    Quido A. Valent;Pier A. Scotti;Stephen High;Jan Willem L De Gier

  • Large-Scale Movement of Elongation Factor G and Extensive Conformational Change of the Ribosome during Translocation

    Holger Stark;Marina V Rodnina;Hans-Joachim Wieden;Marin van Heel

  • An elongation factor G-induced ribosome rearrangement precedes tRNA-mRNA translocation.

    Andreas Savelsbergh;Vladimir I. Katunin;Dagmar Mohr;Frank Peske

  • Arrangement of tRNAs in pre- and posttranslocational ribosomes revealed by electron cryomicroscopy.

    Holger Stark;Elena V Orlova;Elena V Orlova;Jutta Rinke-Appel;Nicole Jünke

  • Conformational switch in the decoding region of 16S rRNA during aminoacyl-tRNA selection on the ribosome

    Tillmann Pape;Wolfgang Wintermeyer;Marina V. Rodnina

  • How ribosomes make peptide bonds

    Marina V. Rodnina;Malte Beringer;Wolfgang Wintermeyer

  • GTP consumption of elongation factor Tu during translation of heteropolymeric mRNAs

    Marina V. Rodnina;Wolfgang Wintermeyer

  • Ribosome interactions of aminoacyl-tRNA and elongation factor Tu in the codon-recognition complex

    H. Stark;M. V. Rodnina;H. J. Wieden;F. Zemlin

  • Thiostrepton inhibits the turnover but not the GTPase of elongation factor G on the ribosome

    Marina V. Rodnina;Andreas Savelsbergh;Natalia B. Matassova;Vladimir I. Katunin

  • Signal sequence-independent membrane targeting of ribosomes containing short nascent peptides within the exit tunnel.

    Thomas Bornemann;Johannes Jöckel;Marina V Rodnina;Wolfgang Wintermeyer

  • Conformational changes of the small ribosomal subunit during elongation factor G-dependent tRNA-mRNA translocation.

    Frank Peske;Andreas Savelsbergh;Vladimir I. Katunin;Marina V. Rodnina

  • GTPase activation of elongation factors Tu and G on the ribosome.

    Dagmar Mohr;Wolfgang Wintermeyer;Marina V. Rodnina

  • Sequence of Steps in Ribosome Recycling as Defined by Kinetic Analysis

    Frank Peske;Marina V. Rodnina;Wolfgang Wintermeyer

  • Important Contribution to Catalysis of Peptide Bond Formation by a Single Ionizing Group within the Ribosome

    Vladimir I Katunin;Gregory W Muth;Scott A Strobel;Wolfgang Wintermeyer

Frequent Co-Authors

Marina V. Rodnina
Marina V. Rodnina Max Planck Society
Holger Stark
Holger Stark Max Planck Society
Hans G. Zachau
Hans G. Zachau Ludwig-Maximilians-Universität München
Richard Brimacombe
Richard Brimacombe Max Planck Society
Claudio O. Gualerzi
Claudio O. Gualerzi University of Camerino
Joen Luirink
Joen Luirink Vrije Universiteit Amsterdam
Rudolf Rigler
Rudolf Rigler Karolinska Institute
Elena V. Orlova
Elena V. Orlova Birkbeck, University of London
Roland Lill
Roland Lill Philipp University of Marburg
Mathias Sprinzl
Mathias Sprinzl University of Bayreuth

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