World's Best Scientists 2026 revealed!

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Chemistry

D-Index
61
Citations
10718
World Ranking
9440
National Ranking
2656

Biology and Biochemistry

D-Index
60
Citations
10936
World Ranking
12119
National Ranking
5188

Research.com Recognitions

  • 2004 - Fellow of the American Association for the Advancement of Science (AAAS)
  • 1974 - Fellow of Alfred P. Sloan Foundation

Overview

Barry S. Cooperman is affiliated with the University of Pennsylvania in the United States. Their research primarily focuses on the field of Biochemistry, Genetics, and Molecular Biology, with a significant emphasis on Molecular Biology as a subfield.

The scientist's work spans several main topics, including:

  • RNA and protein synthesis mechanisms
  • RNA modifications and cancer
  • RNA Research and Splicing
  • Mitochondrial Function and Pathology
  • Viral Infections and Immunology Research
  • Advanced biosensing and bioanalysis techniques
  • Genomics and Phylogenetic Studies

Barry S. Cooperman has published many papers in various scientific venues. Frequent publication venues include:

  • Biophysical Journal (8 publications)
  • bioRxiv (Cold Spring Harbor Laboratory) (4 publications)
  • Nature Communications (2 publications)
  • Nucleic Acids Research (2 publications)
  • Proceedings of the National Academy of Sciences (1 publication)

Some of their recent papers are:

  • "Ataluren and aminoglycosides stimulate read-through of nonsense codons by orthogonal mechanisms," 2021, Proceedings of the National Academy of Sciences
  • "Ataluren binds to multiple protein synthesis apparatus sites and competitively inhibits release factor-dependent termination," 2022, Nature Communications
  • "Human mitochondria require mtRF1 for translation termination at non-canonical stop codons," 2023, Nature Communications
  • "Translation initiation of leaderless and polycistronic transcripts in mammalian mitochondria," 2023, Nucleic Acids Research
  • "Cytosolic and mitochondrial translation elongation are coordinated through the molecular chaperone TRAP1 for the synthesis and import of mitochondrial proteins," 2023, Genome Research

Barry S. Cooperman has collaborated frequently with several co-authors, including:

  • Yale E. Goldman (14 co-authored papers)
  • A.A. Bhattacharya (13 co-authored papers)
  • Clark Fritsch (8 co-authored papers)
  • Saleem Y. Bhat (8 co-authored papers)
  • Martin Y. Ng (7 co-authored papers)

The scientist has received recognition in the form of awards, including being named a Fellow of the American Association for the Advancement of Science (AAAS) in 2004 and a Fellow of the Alfred P. Sloan Foundation in 1974.

Best Publications

  • A double-stranded RNA unwinding activity introduces structural alterations by means of adenosine to inosine conversions in mammalian cells and Xenopus eggs.

    Richard W. Wagner;Joseph E. Smith;Barry S. Cooperman;Kazuko Nishikura

  • Evolutionary conservation of the active site of soluble inorganic pyrophosphatase.

    Barry S. Cooperman;Alexander A. Baykov;Reijo Lahti

  • Crystal structure of an uncleaved serpin reveals the conformation of an inhibitory reactive loop

    Anzhi Wei;Harvey Rubin;Barry S. Cooperman;David W. Christianson

  • Kinetically competent intermediates in the translocation step of protein synthesis.

    Dongli Pan;Stanislav V. Kirillov;Stanislav V. Kirillov;Barry S. Cooperman

  • Cloning, expression, purification, and biological activity of recombinant native and variant human alpha 1-antichymotrypsins.

    H. Rubin;Zhi Mei Wang;E. B. Nickbarg;S. Mclarney

  • Photoincorporation of tetracycline into Escherichia coli ribosomes. Identification of the major proteins photolabeled by native tetracycline and tetracycline photoproducts and implications for the inhibitory action of tetracycline on protein synthesis.

    Robert A. Goldman;Tayyaba Hasan;Clifford C. Hall;William A. Strycharz

  • The structural basis for pyrophosphatase catalysis.

    Pirkko Heikinheimo;Jukka Lehtonen;Alexander Baykov;Reijo Lahti

  • Dynamics of translation by single ribosomes through mRNA secondary structures

    Chunlai Chen;Haibo Zhang;Steven L Broitman;Michael Reiche

  • Reaction of human skin chymotrypsin-like proteinase chymase with plasma proteinase inhibitors.

    N M Schechter;J L Sprows;O L Schoenberger;G S Lazarus

  • Single-molecule fluorescence measurements of ribosomal translocation dynamics.

    Chunlai Chen;Benjamin Stevens;Jaskarin Kaur;Diana Cabral

  • The mechanism of action of yeast inorganic pyrophosphatase.

    Barry S. Cooperman

  • Nonexponential kinetics of a single tRNAPhe molecule under physiological conditions.

    Yiwei Jia;Alexander Sytnik;Liangquan Li;Serguei Vladimirov

  • Engine out of the chassis: Cell-free protein synthesis and its uses

    Gabriel Rosenblum;Barry S. Cooperman

  • Toward a quantum-mechanical description of metal-assisted phosphoryl transfer in pyrophosphatase.

    P. Heikinheimo;V. Tuominen;A.-K. Ahonen;A. Teplyakov

  • A comprehensive model for the allosteric regulation of mammalian ribonucleotide reductase. Functional consequences of ATP- and dATP-induced oligomerization of the large subunit.

    Ossama B. Kashlan;Charles P. Scott;James D. Lear;Barry S. Cooperman

  • Ribosomal protein L2 is involved in the association of the ribosomal subunits, tRNA binding to A and P sites and peptidyl transfer

    Gundo Diedrich;Gundo Diedrich;Christian M. T. Spahn;Christian M. T. Spahn;Ulrich Stelzl;Markus A. Schäfer

  • An unusual route to thermostability disclosed by the comparison of Thermus thermophilus and Escherichia coli inorganic pyrophosphatases.

    Tuna Salminen;Alexei Teplyakov;Jussi Kankare;Barry S. Cooperman

  • Cytoplasmic inorganic pyrophosphatase

    A. A. Baykov;B. S. Cooperman;A. Goldman;R. Lahti

  • A quantitative kinetic scheme for 70 S translation initiation complex formation.

    Christina Grigoriadou;Stefano Marzi;Stanislas Kirillov;Stanislas Kirillov;Claudio O. Gualerzi

  • Comprehensive model for allosteric regulation of mammalian ribonucleotide reductase: refinements and consequences.

    Ossama B. Kashlan;Barry S. Cooperman

Frequent Co-Authors

Yale E. Goldman
Yale E. Goldman University of Pennsylvania
Harvey Rubin
Harvey Rubin University of Pennsylvania
Norman M. Schechter
Norman M. Schechter University of Pennsylvania
Amos B. Smith
Amos B. Smith University of Pennsylvania
Tayyaba Hasan
Tayyaba Hasan Harvard University
Daniel N. Wilson
Daniel N. Wilson Universität Hamburg
David W. Christianson
David W. Christianson University of Pennsylvania
Scott L. Diamond
Scott L. Diamond University of Pennsylvania
Xu Wu
Xu Wu Harvard University
Hieronim Jakubowski
Hieronim Jakubowski Rutgers, The State University of New Jersey

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