World's Best Scientists 2026 revealed!

D-Index & Metrics

Molecular Biology

D-Index
65
Citations
23912
World Ranking
1645
National Ranking
833

Overview

Kazuko Nishikura is a researcher affiliated with The Wistar Institute in the United States. Their work primarily spans the fields of Biochemistry, Genetics and Molecular Biology, and Medicine, with a more focused expertise in Molecular Biology. Their research interests include various subfields such as Epidemiology, Oncology, Cardiology and Cardiovascular Medicine, and Infectious Diseases.

Their scientific contributions concentrate on topics related to RNA regulation and disease, RNA research and splicing, RNA and protein synthesis mechanisms, cytomegalovirus and herpesvirus research, viral-associated cancers and disorders, viral infections and immunology research, and CRISPR and genetic engineering.

They have published extensively in multiple venues, including bioRxiv (Cold Spring Harbor Laboratory), Wiley Interdisciplinary Reviews - RNA, Nature Communications, Nature Cell Biology, and RNA. Their papers cover mechanisms of RNA editing, genome stability, and cellular senescence related to RNA editing enzymes.

  • The role of RNA editing enzyme ADAR1 in human disease, 2021, Wiley Interdisciplinary Reviews - RNA
  • ADAR1 RNA editing enzyme regulates R-loop formation and genome stability at telomeres in cancer cells, 2021, Nature Communications
  • ADAR1 downregulation by autophagy drives senescence independently of RNA editing by enhancing p16INK4a levels, 2022, Nature Cell Biology
  • Processing of Alu small RNAs by DICER/ADAR1 complexes and their RNAi targets, 2020, RNA
  • LANA-Dependent Transcription-Replication Conflicts and R-Loops at the Terminal Repeats (TR) Correlate with KSHV Episome Maintenance, 2025, bioRxiv (Cold Spring Harbor Laboratory)

Frequent co-authors in their research include Yusuke Shiromoto, Moeko Minakuchi, Masayuki Sakurai, Andrew V. Kossenkov, and Atif H. Asghar.

Best Publications

  • TRBP recruits the Dicer complex to Ago2 for microRNA processing and gene silencing.

    Thimmaiah P. Chendrimada;Richard I. Gregory;Easwari Kumaraswamy;Easwari Kumaraswamy;Jessica Norman

  • Functions and Regulation of RNA Editing by ADAR Deaminases

    Kazuko Nishikura

  • Modulation of microRNA processing and expression through RNA editing by ADAR deaminases.

    Weidong Yang;Thimmaiah P Chendrimada;Qingde Wang;Miyoko Higuchi

  • A-to-I editing of coding and non-coding RNAs by ADARs

    Kazuko Nishikura

  • Redirection of Silencing Targets by Adenosine-to-Inosine Editing of miRNAs

    Yukio Kawahara;Boris Zinshteyn;Praveen Sethupathy;Hisashi Iizasa

  • A third member of the RNA-specific adenosine deaminase gene family, ADAR3, contains both single- and double-stranded RNA binding domains.

    Chun-Xia Chen;Dan-Sung C. Cho;Qingde Wang;Fang Lai

  • Dynamic landscape and regulation of RNA editing in mammals

    Meng How Tan;Qin Li;Raghuvaran Shanmugam;Robert Piskol

  • Stress-induced Apoptosis Associated with Null Mutation of ADAR1 RNA Editing Deaminase Gene

    Qingde Wang;Mana Miyakoda;Weidong Yang;Jaspal Khillan

  • Requirement of the RNA editing deaminase ADAR1 gene for embryonic erythropoiesis.

    Q. Wang;J. Khillan;P. Gadue;K. Nishikura

  • RNA editing of the microRNA-151 precursor blocks cleavage by the Dicer–TRBP complex

    Yukio Kawahara;Boris Zinshteyn;Thimmaiah P Chendrimada;Ramin Shiekhattar

  • Molecular cloning of cDNA for double-stranded RNA adenosine deaminase, a candidate enzyme for nuclear RNA editing.

    Unkyu Kim;Yi Wang;Tamara Sanford;Yong Zeng

  • Regulation of innate immune responses by DAI (DLM-1/ZBP1) and other DNA-sensing molecules.

    ZhiChao Wang;Myoung Kwon Choi;Tatsuma Ban;Hideyuki Yanai

  • Differential expression of the translocated and the untranslocated c-myc oncogene in Burkitt lymphoma

    Abbas ar-Rushdi;Kazuko Nishikura;Jan Erikson;Rosemary Watt

  • A Z-DNA binding domain present in the human editing enzyme, double-stranded RNA adenosine deaminase

    Alan Herbert;Jens Alfken;Yang-Gyun Kim;I. Saira Mian

  • Frequency and fate of microRNA editing in human brain

    Yukio Kawahara;Molly Megraw;Edward Kreider;Hisashi Iizasa

  • Editor meets silencer: crosstalk between RNA editing and RNA interference

    Kazuko Nishikura

  • A-to-I RNA editing and human disease.

    Stefan Maas;Yukio Kawahara;Kristen M Tamburro;Kazuko Nishikura

  • ADAR1 Forms a Complex with Dicer to Promote MicroRNA Processing and RNA-Induced Gene Silencing

    Hiromitsu Ota;Masayuki Sakurai;Ravi Gupta;Louis Valente

  • A Short Primer on RNAi: RNA-Directed RNA Polymerase Acts as a Key Catalyst

    Kazuko Nishikura

  • Adenosine-to-inosine RNA editing and human disease

    William Slotkin;Kazuko Nishikura

Frequent Co-Authors

Jan Erikson
Jan Erikson The Wistar Institute
Carlo M. Croce
Carlo M. Croce The Ohio State University
Ramin Shiekhattar
Ramin Shiekhattar University of Miami
Peter C. Nowell
Peter C. Nowell University of Pennsylvania
Louise C. Showe
Louise C. Showe The Wistar Institute
Charles E. Samuel
Charles E. Samuel University of California, Santa Barbara
Andrew V. Kossenkov
Andrew V. Kossenkov The Wistar Institute
Tomohiko Tamura
Tomohiko Tamura Yokohama City University
Julie A. Blendy
Julie A. Blendy University of Pennsylvania
Beverly S. Emanuel
Beverly S. Emanuel Children's Hospital of Philadelphia

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Exploring molecular biology can open doors to a variety of online healthcare and science degrees in the USA. For students with a communication sciences background, slp bridge programs offer a pathway into speech-language pathology, bridging the gap for those who didn’t major in the field.

If you're considering a shift into nursing, there are accelerated nursing programs for non nurses online that allow science graduates to qualify as registered nurses in a shorter time frame. These flexible, online pathways help career changers transition quickly into high-demand healthcare roles.

For those interested in mental health, becoming a nurse practitioner can be a rewarding goal. Researching psychiatric mental health nurse practitioner salary by state can help you assess financial outcomes across different regions. Additionally, understanding how long does it take to be a nurse practitioner can guide your educational planning for a streamlined career transition.

Best Scientists Citing Kazuko Nishikura

Trending Scientists

Recently Published Articles