World's Best Scientists 2026 revealed!

D-Index & Metrics

Chemistry

D-Index
47
Citations
8144
World Ranking
15627
National Ranking
3934

Punit P. Seth publication distribution in Chemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Chemistry in 2026. The highlighted bar marks where Punit P. Seth sits on this spectrum.

61–80 publications: 66 scientists 81–100 publications: 302 scientists 101–120 publications: 623 scientists 121–140 publications: 918 scientists 141–160 publications: 1,218 scientists 161–180 publications: 1,350 scientists 181–200 publications: 1,344 scientists 201–220 publications: 1,281 scientists 221–240 publications: 1,216 scientists 241–260 publications: 1,100 scientists 261–280 publications: 979 scientists 281–300 publications: 939 scientists 301–320 publications: 764 scientists 321–340 publications: 643 scientists 341–360 publications: 628 scientists 361–380 publications: 522 scientists 381–400 publications: 459 scientists 401–420 publications: 397 scientists 421–440 publications: 327 scientists 441–460 publications: 270 scientists 461–480 publications: 265 scientists 481–500 publications: 252 scientists 501–520 publications: 201 scientists 521–540 publications: 185 scientists 541–560 publications: 148 scientists 561–580 publications: 148 scientists 581–600 publications: 132 scientists 601–620 publications: 114 scientists 621–640 publications: 104 scientists 641–660 publications: 91 scientists 661–680 publications: 92 scientists 681–700 publications: 73 scientists 701–720 publications: 57 scientists 721–740 publications: 54 scientists 741–760 publications: 67 scientists 761–780 publications: 45 scientists 781–800 publications: 46 scientists 801–820 publications: 39 scientists 821–840 publications: 32 scientists 841–860 publications: 36 scientists 861–880 publications: 29 scientists 881–900 publications: 26 scientists 901–920 publications: 24 scientists 921–940 publications: 14 scientists 941–960 publications: 23 scientists 961–980 publications: 28 scientists 981–1,000 publications: 15 scientists 1,001–1,020 publications: 29 scientists 1,021–1,040 publications: 12 scientists 1,041–1,060 publications: 19 scientists 1,061–1,080 publications: 12 scientists 1,081–1,100 publications: 6 scientists 1,101–1,120 publications: 8 scientists 1,121–1,140 publications: 12 scientists 1,141–1,160 publications: 5 scientists 1,161–1,180 publications: 6 scientists 1,181–1,200 publications: 14 scientists 1,201–1,220 publications: 7 scientists 1,221–1,240 publications: 2 scientists 1,241–1,260 publications: 6 scientists 1,261–1,280 publications: 4 scientists 1,281–1,294 publications: 6 scientists 1,295+ publications: 100 scientists
61 publications 1,295+

This scientist: 145 publications — 12th percentile

12% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,295 publications or more.

Punit P. Seth D-index placement in Chemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Chemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Punit P. Seth sits on this spectrum.

40–41 D-Index: 289 scientists 42–43 D-Index: 612 scientists 44–45 D-Index: 808 scientists 46–47 D-Index: 776 scientists 48–49 D-Index: 835 scientists 50–51 D-Index: 861 scientists 52–53 D-Index: 872 scientists 54–55 D-Index: 933 scientists 56–57 D-Index: 1,051 scientists 58–59 D-Index: 930 scientists 60–61 D-Index: 882 scientists 62–63 D-Index: 834 scientists 64–65 D-Index: 731 scientists 66–67 D-Index: 775 scientists 68–69 D-Index: 683 scientists 70–71 D-Index: 646 scientists 72–73 D-Index: 561 scientists 74–75 D-Index: 501 scientists 76–77 D-Index: 437 scientists 78–79 D-Index: 388 scientists 80–81 D-Index: 354 scientists 82–83 D-Index: 292 scientists 84–85 D-Index: 275 scientists 86–87 D-Index: 254 scientists 88–89 D-Index: 235 scientists 90–91 D-Index: 185 scientists 92–93 D-Index: 192 scientists 94–95 D-Index: 155 scientists 96–97 D-Index: 163 scientists 98–99 D-Index: 125 scientists 100–101 D-Index: 105 scientists 102–103 D-Index: 105 scientists 104–105 D-Index: 112 scientists 106–107 D-Index: 88 scientists 108–109 D-Index: 68 scientists 110–111 D-Index: 69 scientists 112–113 D-Index: 65 scientists 114–115 D-Index: 79 scientists 116–117 D-Index: 61 scientists 118–119 D-Index: 44 scientists 120–121 D-Index: 37 scientists 122–123 D-Index: 40 scientists 124–125 D-Index: 33 scientists 126–127 D-Index: 26 scientists 128–129 D-Index: 34 scientists 130–131 D-Index: 35 scientists 132–133 D-Index: 25 scientists 134–135 D-Index: 27 scientists 136–137 D-Index: 17 scientists 138–139 D-Index: 16 scientists 140–141 D-Index: 20 scientists 142–143 D-Index: 20 scientists 144–145 D-Index: 15 scientists 146–147 D-Index: 9 scientists 148–149 D-Index: 9 scientists 150–151 D-Index: 16 scientists 152–153 D-Index: 11 scientists 154–155 D-Index: 9 scientists 156–157 D-Index: 3 scientists 158 D-Index: 3 scientists 159+ D-Index: 98 scientists
40 D-Index 159+

This scientist: 47 D-Index — 14th percentile

14% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 159 D-Index or more.

Overview

Punit P. Seth is affiliated with Ionis Pharmaceuticals in the United States. Their research primarily focuses on the field of Biochemistry, Genetics and Molecular Biology, where they have contributed extensively, particularly in Molecular Biology. Their work also intersects with subfields such as Pulmonary and Respiratory Medicine, Radiology, Nuclear Medicine and Imaging, Biophysics, and Rheumatology.

The scientist's main research topics include:

  • Advanced biosensing and bioanalysis techniques
  • RNA Interference and Gene Delivery
  • DNA and Nucleic Acid Chemistry
  • RNA and protein synthesis mechanisms
  • RNA Research and Splicing
  • CRISPR and Genetic Engineering
  • RNA regulation and disease

Punit P. Seth has published frequently in several scientific journals. The most common publication venues are:

  • Nucleic Acids Research (9 publications)
  • Journal of the American Chemical Society (6 publications)
  • Nucleic Acid Therapeutics (4 publications)
  • Nature Biotechnology (1 publication)
  • Trends in Pharmacological Sciences (1 publication)

Their recent notable papers include:

  • "Cholesterol-functionalized DNA/RNA heteroduplexes cross the blood-brain barrier and knock down genes in the rodent CNS," 2021, Nature Biotechnology
  • "The Interaction of Phosphorothioate-Containing RNA Targeted Drugs with Proteins Is a Critical Determinant of the Therapeutic Effects of These Agents," 2020, Journal of the American Chemical Society
  • "Towards next generation antisense oligonucleotides: mesylphosphoramidate modification improves therapeutic index and duration of effect of gapmer antisense oligonucleotides," 2021, Nucleic Acids Research
  • "Understanding the effect of controlling phosphorothioate chirality in the DNA gap on the potency and safety of gapmer antisense oligonucleotides," 2020, Nucleic Acids Research
  • "Origins of the Increased Affinity of Phosphorothioate-Modified Therapeutic Nucleic Acids for Proteins," 2020, Journal of the American Chemical Society

Frequent co-authors of Punit P. Seth comprise:

  • Michael T. Migawa
  • Eric E. Swayze
  • Stanley T. Crooke
  • Xue-hai Liang
  • Graeme C. Freestone

Best Publications

  • 6-modified bicyclic nucleic acid analogs

    Eric E. Swayze;Punit P. Seth

  • The Medicinal Chemistry of Therapeutic Oligonucleotides

    W. Brad Wan;Punit P. Seth

  • 5′-modified bicyclic nucleic acid analogs

    Punit P. Seth;Eric E. Swayze

  • Chemical modification of PS-ASO therapeutics reduces cellular protein-binding and improves the therapeutic index.

    Wen Shen;Cheryl L. De Hoyos;Michael T. Migawa;Timothy A. Vickers

  • Single-stranded siRNAs activate RNAi in animals

    Walt F. Lima;Thazha P. Prakash;Heather M. Murray;Garth A. Kinberger

  • Short antisense oligonucleotides with novel 2'-4' conformationaly restricted nucleoside analogues show improved potency without increased toxicity in animals.

    Punit P. Seth;Andrew Siwkowski;Charles R. Allerson;Guillermo Vasquez

  • Carbocyclic alpha-l-bicyclic nucleic acid analogs

    Punit P. Seth;Eric E. Swayze

  • Substituted alpha-l-bicyclic nucleosides

    Punit P. Seth;Eric E. Swayze

  • Synthesis and biophysical evaluation of 2',4'-constrained 2'O-methoxyethyl and 2',4'-constrained 2'O-ethyl nucleic acid analogues.

    Punit P. Seth;Guillermo Vasquez;Charles A. Allerson;Andres Berdeja

  • Bicyclic cyclohexose nucleic acid analogs

    Michael T. Migawa;Punit P. Seth;Eric E. Swayze;Bruce S. Ross

  • Conjugated antisense compounds and their use

    Thazha P. Prakash;Punit P. Seth;Eric E. Swayze

  • SAR by MS: Discovery of a New Class of RNA-Binding Small Molecules for the Hepatitis C Virus: Internal Ribosome Entry Site IIA Subdomain

    Punit P. Seth;Alycia Miyaji;Elizabeth A. Jefferson;Kristin A. Sannes-Lowery

  • Compounds and methods for synthesis of bicyclic nucleic acid analogs

    Balkrishen Bhat;Jie Xia;Punit P. Seth;Guillermo Vasquez

  • Compounds and methods for modulating gene expression

    Sanjay Bhanot;Richard S. Geary;Robert Mckay;Brett P. Monia

  • Targeted delivery of antisense oligonucleotides to pancreatic β-cells.

    C. Ämmälä;W. J. Drury;L. Knerr;I. Ahlstedt

  • Asialoglycoprotein receptor 1 mediates productive uptake of N-acetylgalactosamine-conjugated and unconjugated phosphorothioate antisense oligonucleotides into liver hepatocytes.

    Michael Tanowitz;Lisa Hettrick;Alexey Revenko;Garth A Kinberger

  • Synthesis, biophysical properties and biological activity of second generation antisense oligonucleotides containing chiral phosphorothioate linkages

    W. Brad Wan;Michael T. Migawa;Guillermo Vasquez;Heather M. Murray

  • Stabilin-1 and Stabilin-2 are specific receptors for the cellular internalization of phosphorothioate-modified antisense oligonucleotides (ASOs) in the liver

    Colton M. Miller;Aaron J. Donner;Emma E. Blank;Andrew W. Egger

  • DNA/RNA heteroduplex oligonucleotide for highly efficient gene silencing

    Kazutaka Nishina;Wenying Piao;Kie Yoshida-Tanaka;Yumiko Sujino

  • Characterization of the interactions of chemically-modified therapeutic nucleic acids with plasma proteins using a fluorescence polarization assay.

    Hans J Gaus;Ruchi Gupta;Alfred E Chappell;Michael E Østergaard

  • Design, Synthesis And Evaluation Of Constrained Methoxyethyl (cMOE) and Constrained Ethyl (cEt) Nucleoside Analogs

    Punit P Seth;Andrew Siwkowski;Charles R Allerson;Guillermo Vasquez

  • Fatty acid conjugation enhances potency of antisense oligonucleotides in muscle

    Thazha P Prakash;Adam E Mullick;Richard G Lee;Jinghua Yu

  • Compounds and methods for modulating expression of apob

    ブハノト サンジャイ;Bhanot Sanjay;エス.ゲアリ リチャルド;Richard S Geary

  • Comprehensive Structure-Activity Relationship of Triantennary N-Acetylgalactosamine Conjugated Antisense Oligonucleotides for Targeted Delivery to Hepatocytes

    Thazha P. Prakash;Jinghua Yu;Michael T. Migawa;Garth A. Kinberger

  • Cholesterol-functionalized DNA/RNA heteroduplexes cross the blood–brain barrier and knock down genes in the rodent CNS

    Tetsuya Nagata;Chrissa A. Dwyer;Kie Yoshida-Tanaka;Kensuke Ihara

  • An exocyclic methylene group acts as a bioisostere of the 2'-oxygen atom in LNA.

    Punit P Seth;Charles R. Allerson;Andres Berdeja;Andrew Siwkowski

  • Identification of metabolically stable 5′-phosphate analogs that support single-stranded siRNA activity

    Thazha P. Prakash;Walt F. Lima;Heather M. Murray;Wenyu Li

  • Selective tissue targeting of synthetic nucleic acid drugs

    Punit P. Seth;Michael Tanowitz;C. Frank Bennett

  • Towards next generation antisense oligonucleotides: mesylphosphoramidate modification improves therapeutic index and duration of effect of gapmer antisense oligonucleotides.

    Brooke A Anderson;Graeme C Freestone;Audrey Low;Cheryl L De-Hoyos

Frequent Co-Authors

Eric E. Swayze
Eric E. Swayze Ionis Pharmaceuticals (United States)
Richard S. Geary
Richard S. Geary Ionis Pharmaceuticals (United States)
Stanley T. Crooke
Stanley T. Crooke Ionis Pharmaceuticals (United States)
C. Frank Bennett
C. Frank Bennett Ionis Pharmaceuticals (United States)
Stephen Hanessian
Stephen Hanessian University of Montreal
Michael R. Hayden
Michael R. Hayden University of British Columbia
Brett P. Monia
Brett P. Monia Ionis Pharmaceuticals (United States)
Frank Rigo
Frank Rigo Ionis Pharmaceuticals (United States)
Martin Egli
Martin Egli Vanderbilt University
Susan M. Freier
Susan M. Freier Ionis Pharmaceuticals (United States)

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