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Chemistry

D-Index
128
Citations
47622
World Ranking
367
National Ranking
164

Research.com Recognitions

  • 1981 - Fellow of Alfred P. Sloan Foundation

Overview

R. Mark Wightman is affiliated with the University of North Carolina at Chapel Hill in the United States. Their research primarily spans the field of Neuroscience, with a focus on Cellular and Molecular Neuroscience, Cognitive Neuroscience, and Molecular Biology. Additional areas of expertise include Electrical and Electronic Engineering and Electrochemistry.

The scientist's work encompasses multiple topics such as Neuroscience and Neuropharmacology Research, Neurotransmitter Receptor Influence on Behavior, Electrochemical Analysis and Applications, Functional Brain Connectivity Studies, Analytical Chemistry and Sensors, Neural Dynamics and Brain Function, and Electrochemical Sensors and Biosensors.

Wightman has contributed extensively to the academic community, with a significant number of publications appearing in venues like UNC Libraries, OPAL (Open@LaTrobe) at La Trobe University, and NeuroImage. The UNC Libraries alone include 76 of their works, alongside publications in OPAL, NeuroImage, bioRxiv (Cold Spring Harbor Laboratory), and e-Publications@Marquette (Marquette University).

Frequent collaborators include Regina M. Carelli, Pavel Takmakov, Richard B. Keithley, Gregory S. McCarty, and Paul E. M. Phillips.

Notable recent papers authored or coauthored by Wightman include:

  • "Different kinetics govern dopaminergic transmission in the amygdala, prefrontal cortex, and striatum: an in vivo voltammetric study" (2021, UNC Libraries)
  • "Synaptic Overflow of Dopamine in the Nucleus Accumbens Arises from Neuronal Activity in the Ventral Tegmental Area" (2020, UNC Libraries)
  • "Simultaneous fMRI and fast-scan cyclic voltammetry bridges evoked oxygen and neurotransmitter dynamics across spatiotemporal scales" (2021, NeuroImage)
  • "Aversive stimulus differentially triggers subsecond dopamine release in reward regions" (2020, UNC Libraries)
  • "Time course of release of catecholamines from individual vesicles during exocytosis at adrenal medullary cells" (2020, UNC Libraries)

In recognition of their contributions, Wightman was named a Fellow of the Alfred P. Sloan Foundation in 1981.

Best Publications

  • Subsecond dopamine release promotes cocaine seeking

    Paul E. M. Phillips;Garret D. Stuber;Michael L. A. V. Heien;R. Mark Wightman

  • Detection of dopamine dynamics in the brain

    R. Mark Wightman;Leslie J. May;Adrian C. Michael

  • Temporally resolved catecholamine spikes correspond to single vesicle release from individual chromaffin cells

    R. M. Wightman;J. A. Jankowski;R. T. Kennedy;K. T. Kawagoe

  • Dopamine Operates as a Subsecond Modulator of Food Seeking

    Mitchell F. Roitman;Garret D. Stuber;Paul E. M. Phillips;R. Mark Wightman

  • Monitoring Rapid Chemical Communication in the Brain

    Donita L. Robinson;Andre Hermans;Andrew T. Seipel;R. Mark Wightman

  • Detecting subsecond dopamine release with fast-scan cyclic voltammetry in vivo.

    Donita L Robinson;B. Jill Venton;Michael L A V Heien;R Mark Mark Wightman

  • Real-time measurement of dopamine fluctuations after cocaine in the brain of behaving rats

    Michael L. A. V. Heien;Amina S. Khan;Jennifer L. Ariansen;Joseph F. Cheer

  • Real-time characterization of dopamine overflow and uptake in the rat striatum.

    R.M. Wightman;C. Amatorh;R.C. Engstrom;P.D. Hale

  • Psychoanalytical Electrochemistry: Dopamine and Behavior

    B. Jill Venton;R. Mark Wightman

  • Probing Cellular Chemistry in Biological Systems with Microelectrodes

    R. Mark Wightman

  • Dissociation of dopamine release in the nucleus accumbens from intracranial self-stimulation.

    Paul A. Garris;Michaux Kilpatrick;Melissa A. Bunin;Darren Michael

  • Knockout of the Vesicular Monoamine Transporter 2 Gene Results in Neonatal Death and Supersensitivity to Cocaine and Amphetamine

    Yan Min Wang;Raul R. Gainetdinov;Fabio Fumagalli;Fei Xu

  • Overoxidation of carbon-fiber microelectrodes enhances dopamine adsorption and increases sensitivity.

    Michael L. A. V. Heien;Paul E. M. Phillips;Garret D. Stuber;Andrew T. Seipel

  • Cannabinoids Enhance Subsecond Dopamine Release in the Nucleus Accumbens of Awake Rats

    Joseph F. Cheer;Kate M. Wassum;Michael L. A. V. Heien;Paul E. M. Phillips

  • Resolving neurotransmitters detected by fast-scan cyclic voltammetry.

    Michael L A V Heien;Michael A Johnson;R Mark Wightman

  • Subsecond adsorption and desorption of dopamine at carbon-fiber microelectrodes.

    Bradley D. Bath;Darren J. Michael;B. Jill Trafton;Joshua D. Joseph

  • Phasic dopamine release evoked by abused substances requires cannabinoid receptor activation.

    Joseph F. Cheer;Kate M. Wassum;Leslie A. Sombers;Michael L A V Heien

  • Principles of voltammetry and microelectrode surface states

    Unknown

  • Real-time chemical responses in the nucleus accumbens differentiate rewarding and aversive stimuli

    Mitchell F Roitman;Robert A Wheeler;R Mark Wightman;Regina M Carelli

  • Fast-scan voltammetry of biogenic amines

    John E. Baur;Eric W. Kristensen;Leslie J. May;Donna J. Wiedemann

  • Voltammetry with microscopic electrodes in new domains.

    R. Mark Wightman

Frequent Co-Authors

Regina M. Carelli
Regina M. Carelli University of North Carolina at Chapel Hill
Paul E. M. Phillips
Paul E. M. Phillips University of Washington
Sara R. Jones
Sara R. Jones Wake Forest University
Andrew G. Ewing
Andrew G. Ewing University of Gothenburg
Christian Amatore
Christian Amatore École Normale Supérieure
Paul A. Garris
Paul A. Garris Illinois State University
Evgeny A. Budygin
Evgeny A. Budygin Wake Forest University
Raul R. Gainetdinov
Raul R. Gainetdinov Saint Petersburg State University
Marc G. Caron
Marc G. Caron Duke University
Garret D. Stuber
Garret D. Stuber University of Washington

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