World's Best Scientists 2026 revealed!

D-Index & Metrics

Neuroscience

D-Index
115
Citations
67582
World Ranking
445
National Ranking
261

Medicine

D-Index
115
Citations
67584
World Ranking
4454
National Ranking
2427

Overview

David Sulzer is affiliated with Columbia University in the United States and has an extensive research portfolio primarily focused on neuroscience and medicine. Their scholarly work spans over 113 publications in neuroscience and 102 in medicine, indicating a broad and interdisciplinary approach to biomedical research.

The main subfields of study contributing to Sulzer's research include neurology, cellular and molecular neuroscience, molecular biology, immunology, and cell biology. These areas highlight a concentrated effort on understanding disease mechanisms at cellular and molecular levels as well as immune system interactions within neurological contexts.

The scientist's research topics cover:

  • Parkinson's Disease Mechanisms and Treatments
  • Neuroscience and Neuropharmacology Research
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Nuclear Receptors and Signaling
  • Neurotransmitter Receptor Influence on Behavior
  • Receptor Mechanisms and Signaling
  • Neurological Disorders and Treatments

David Sulzer has contributed a number of recent papers in prominent journals, which include:

  • "α-Synuclein-specific T cell reactivity is associated with preclinical and early Parkinson's disease," 2020, Nature Communications
  • "Chaperone-mediated autophagy prevents collapse of the neuronal metastable proteome," 2021, Cell
  • "COVID-19 and possible links with Parkinson's disease and parkinsonism: from bench to bedside," 2020, npj Parkinson's Disease
  • "Alpha-synuclein research: defining strategic moves in the battle against Parkinson's disease," 2021, npj Parkinson's Disease
  • "Mutant glucocerebrosidase impairs α-synuclein degradation by blockade of chaperone-mediated autophagy," 2022, Science Advances

The scientist collaborates frequently with other researchers, with their most frequent co-authors being Alessandro Sette, Cecilia S. Lindestam Arlehamn, April Frazier, Eugene V. Mosharov, and Jennifer G. Goldman. These collaborations reflect interdisciplinary and team-driven research efforts.

David Sulzer's work is regularly published in several specialized venues including bioRxiv (Cold Spring Harbor Laboratory), Zenodo (CERN European Organization for Nuclear Research), npj Parkinson's Disease, Neurobiology of Disease, and Cell Reports. This variety demonstrates a presence in both preprint repositories and peer-reviewed journals focused on neuroscience and neurological disease.

In addition to research articles, Sulzer has contributed to academic books, with a noted publication titled "Music, Math, and Mind," released in 2021 by Columbia University Press.

Best Publications

  • Guidelines for the use and interpretation of assays for monitoring autophagy

    Daniel J. Klionsky;Fabio C. Abdalla;Hagai Abeliovich;Robert T. Abraham

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes

    Daniel J. Klionsky;Hagai Abeliovich;Patrizia Agostinis;Devendra K. Agrawal

  • Impaired degradation of mutant α-synuclein by chaperone-mediated autophagy

    Ana Maria Cuervo;Leonidas Stefanis;Ross Fredenburg;Peter T. Lansbury

  • Mice Lacking α-Synuclein Display Functional Deficits in the Nigrostriatal Dopamine System

    Asa Abeliovich;Yvonne Schmitz;Isabel Fariñas;Derek Choi-Lundberg

  • Mechanisms of neurotransmitter release by amphetamines: a review.

    David Sulzer;Mark S. Sonders;Nathan W. Poulsen;Aurelio Galli

  • Loss of mTOR-Dependent Macroautophagy Causes Autistic-like Synaptic Pruning Deficits

    Guomei Tang;Kathryn Gudsnuk;Sheng-Han Kuo;Marisa L. Cotrina;Marisa L. Cotrina

  • Cargo recognition failure is responsible for inefficient autophagy in Huntington's disease

    Marta Martinez-Vicente;Marta Martinez-Vicente;Zsolt Talloczy;Zsolt Talloczy;Esther Wong;Guomei Tang

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • T cells from patients with Parkinson’s disease recognize α-synuclein peptides

    David Sulzer;Roy N. Alcalay;Francesca Garretti;Lucien Cote

  • Amphetamine redistributes dopamine from synaptic vesicles to the cytosol and promotes reverse transport

    David Sulzer;Ta Kung Chen;Yau Yi Lau;Helle Kristensen

  • Dopamine-modified α-synuclein blocks chaperone-mediated autophagy

    Marta Martinez-Vicente;Zsolt Talloczy;Susmita Kaushik;Ashish C. Massey

  • Resistance of alpha -synuclein null mice to the parkinsonian neurotoxin MPTP.

    William Dauer;Nikolai Kholodilov;Miquel Vila;Anne Cecile Trillat

  • Multiple hit hypotheses for dopamine neuron loss in Parkinson's disease

    David Sulzer

  • The identification of vesicular glutamate transporter 3 suggests novel modes of signaling by glutamate.

    Robert T. Fremeau;Jonathon Burman;Tayyaba Qureshi;Cindy H. Tran

  • Interactions of iron, dopamine and neuromelanin pathways in brain aging and Parkinson's disease.

    Fabio A. Zucca;Juan Segura-Aguilar;Emanuele Ferrari;Patricia Muñoz

  • Interplay of LRRK2 with chaperone-mediated autophagy

    Samantha J. Orenstein;Sheng-Hang Kuo;Inmaculada Tasset;Esperanza Arias

  • Dopamine release from the locus coeruleus to the dorsal hippocampus promotes spatial learning and memory

    Kimberly A. Kempadoo;Eugene V. Mosharov;Se Joon Choi;Se Joon Choi;David Sulzer;David Sulzer

  • Interplay between Cytosolic Dopamine, Calcium, and α-Synuclein Causes Selective Death of Substantia Nigra Neurons

    Eugene V. Mosharov;Kristin E. Larsen;Ellen Kanter;Kester A. Phillips

  • How addictive drugs disrupt presynaptic dopamine neurotransmission.

    David Sulzer

  • Expression of A53T Mutant But Not Wild-Type α-Synuclein in PC12 Cells Induces Alterations of the Ubiquitin-Dependent Degradation System, Loss of Dopamine Release, and Autophagic Cell Death

    Leonidas Stefanis;Kristin E. Larsen;Hardy J. Rideout;David Sulzer

Frequent Co-Authors

Luigi Zecca
Luigi Zecca National Academies of Sciences, Engineering, and Medicine
Dalibor Sames
Dalibor Sames Columbia University
Alessandro Sette
Alessandro Sette La Jolla Institute For Allergy & Immunology
Stephen Rayport
Stephen Rayport Columbia University
Robert H. Edwards
Robert H. Edwards University of California, San Francisco
Serge Przedborski
Serge Przedborski Columbia University
Ana Maria Cuervo
Ana Maria Cuervo Albert Einstein College of Medicine
Sheng-Han Kuo
Sheng-Han Kuo Columbia University Medical Center
Un Jung Kang
Un Jung Kang New York University
Bjoern Peters
Bjoern Peters La Jolla Institute For Allergy & Immunology

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