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Chemistry

D-Index
65
Citations
16524
World Ranking
7603
National Ranking
2226

Research.com Recognitions

  • 2002 - Fellow of Alfred P. Sloan Foundation

Overview

Dalibor Sames is affiliated with Columbia University in the United States and focuses on research primarily in Neuroscience and Biochemistry, Genetics and Molecular Biology. Their work spans several specialized subfields including Cellular and Molecular Neuroscience, Organic Chemistry, Pharmacology, Clinical Psychology, and Molecular Biology.

The scientist's research explores core topics such as Chemical synthesis and alkaloids, Alkaloids: synthesis and pharmacology, Neurotransmitter receptor influence on behavior, Psychedelics and drug studies, Neuroscience and neuropharmacology research, Traditional and medicinal uses of Annonaceae, and Parkinson's disease mechanisms and treatments.

Frequent co-authors in their publications include David Sulzer, Susruta Majumdar, Jonathan A. Javitch, Václav Havel, and Andrew C. Kruegel. These collaborations reflect consistent partnerships across various projects.

Dalibor Sames has published multiple papers in notable scientific journals. Among their recent papers are:

  • A Novel Mitragynine Analog with Low-Efficacy Mu Opioid Receptor Agonism Displays Antinociception with Attenuated Adverse Effects (2021, Journal of Medicinal Chemistry)
  • Structural pharmacology and therapeutic potential of 5-methoxytryptamines (2024, Nature)
  • Pharmacological Mechanism of the Non-hallucinogenic 5-HT2A Agonist Ariadne and Analogs (2022, ACS Chemical Neuroscience)
  • Oxidative Metabolism as a Modulator of Kratom's Biological Actions (2021, Journal of Medicinal Chemistry)
  • Dopamine transporter and synaptic vesicle sorting defects underlie auxilin-associated Parkinson's disease (2023, Cell Reports)

Sames regularly contributes to several publication venues, including:

  • ACS Chemical Neuroscience
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal of Medicinal Chemistry
  • Journal of the American Chemical Society
  • Nature Communications

Their work has also been recognized with awards such as the Fellow of Alfred P. Sloan Foundation in 2002.

Best Publications

  • C-H Bond Functionalization in Complex Organic Synthesis

    Kamil Godula;Dalibor Sames

  • Direct palladium-catalyzed C-2 and C-3 arylation of indoles: a mechanistic rationale for regioselectivity.

    Benjamin S Lane;Meghann A Brown;Dalibor Sames

  • Direct C-arylation of free (NH)-indoles and pyrroles catalyzed by Ar-Rh(III) complexes assembled in situ.

    Xiang Wang;Benjamin S. Lane;Dalibor Sames

  • sp3 C−H Bond Arylation Directed by Amidine Protecting Group: α-Arylation of Pyrrolidines and Piperidines

    Stefan J. Pastine;Denis V. Gribkov;Dalibor Sames

  • Direct C-H bond arylation: selective palladium-catalyzed C2-arylation of N-substituted indoles.

    Benjamin S. Lane;Dalibor Sames

  • Ru(III)-Catalyzed Cyclization of Arene-Alkene Substrates via Intramolecular Electrophilic Hydroarylation

    Stefan J Pastine;So Won Youn;Dalibor Sames

  • Catalytic C−H Arylation of SEM-Protected Azoles with Palladium Complexes of NHCs and Phosphines

    B. Barry Touré;Benjamin S. Lane;Dalibor Sames

  • Phosphine-free palladium-catalyzed C-H bond arylation of free (N-H)-indoles and pyrroles.

    Xiang Wang;Denis V. Gribkov;Dalibor Sames

  • Synthetic and Receptor Signaling Explorations of the Mitragyna Alkaloids: Mitragynine as an Atypical Molecular Framework for Opioid Receptor Modulators.

    Andrew C. Kruegel;Madalee M. Gassaway;Abhijeet Kapoor;András Váradi

  • Room temperature hydroalkylation of electron-deficient olefins: sp3 C-H functionalization via a lewis acid-catalyzed intramolecular redox event.

    Stefan J Pastine;Kevin M McQuaid;Dalibor Sames

  • Synthetic and Immunological Studies on Clustered Modes of Mucin-Related Tn and TF O-Linked Antigens: The Preparation of a Glycopeptide-Based Vaccine for Clinical Trials against Prostate Cancer†

    Scott D. Kuduk;Jacob B. Schwarz;Xiao-Tao Chen;Peter W. Glunz

  • Selective functionalization of amino acids in water: a synthetic method via catalytic C-H bond activation.

    Brian D. Dangel;James A. Johnson;Dalibor Sames

  • C−H Bond Functionalization via Hydride Transfer: Lewis Acid Catalyzed Alkylation Reactions by Direct Intramolecular Coupling of sp3 C−H Bonds and Reactive Alkenyl Oxocarbenium Intermediates

    Kevin M. McQuaid;Dalibor Sames

  • C-H bonds as ubiquitous functionality: a general approach to complex arylated pyrazoles via sequential regioselective C-arylation and N-alkylation enabled by SEM-group transposition.

    Roman Goikhman;Teresa L. Jacques;Dalibor Sames

  • Fully synthetic carbohydrate-based vaccines in biochemically relapsed prostate cancer: clinical trial results with alpha-N-acetylgalactosamine-O-serine/threonine conjugate vaccine.

    Susan F. Slovin;Govindaswami Ragupathi;Cristina Musselli;Krystyna Olkiewicz

  • Cocktails of Tb(3+) and Eu(3+) complexes: a general platform for the design of ratiometric optical probes.

    Matthew S Tremblay;Marlin Halim;Dalibor Sames

  • Total synthesis of (-)-rhazinilam: Asymmetric C-H bond activation via the use of a chiral auxiliary

    James A. Johnson;Ning Li;Dalibor Sames

  • C-C bond formation via C-H bond activation: synthesis of the core of teleocidin B4.

    Brian D. Dangel;Kamil Godula;So Won Youn;Bengü Sezen

  • Principles of Mucin Architecture: Structural Studies on Synthetic Glycopeptides Bearing Clustered Mono-, Di-, Tri-, and Hexasaccharide Glycodomains

    Don M. Coltart;Ajay K. Royyuru;Lawrence J. Williams;Peter W. Glunz

  • Pt(IV)-catalyzed cyclization of arene–alkyne substrates via C–H bond functionalization

    Stefan J Pastine;So Won Youn;Dalibor Sames

  • The Behavioral Effects of the Antidepressant Tianeptine Require the Mu-Opioid Receptor

    Benjamin Adam Samuels;Katherine M Nautiyal;Andrew C Kruegel;Marjorie R Levinstein

  • C-H bond functionalization in complex organic synthesis

    Dalibor Sames

Frequent Co-Authors

David Sulzer
David Sulzer Columbia University
Jonathan A. Javitch
Jonathan A. Javitch Columbia University
Samuel J. Danishefsky
Samuel J. Danishefsky Columbia University
Steffen Jockusch
Steffen Jockusch Bowling Green State University
Nicholas J. Turro
Nicholas J. Turro Columbia University
Min Hee Lee
Min Hee Lee Sookmyung Women's University
Philip O. Livingston
Philip O. Livingston Memorial Sloan Kettering Cancer Center
Young-Tae Chang
Young-Tae Chang Pohang University of Science and Technology
Robert H. Edwards
Robert H. Edwards University of California, San Francisco
John E. Pintar
John E. Pintar Rutgers, The State University of New Jersey

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