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Chemistry
Korea
2025
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Biology and Biochemistry
Korea
2023

D-Index & Metrics

Chemistry

D-Index
90
Citations
29181
World Ranking
2065
National Ranking
26

Biology and Biochemistry

D-Index
89
Citations
28874
World Ranking
2558
National Ranking
12

Research.com Recognitions

  • 2025 - Research.com Chemistry in Korea Leader Award
  • 2023 - Research.com Biology and Biochemistry in Korea Leader Award
  • 2022 - Research.com Biology and Biochemistry in Korea Leader Award
  • 2022 - Research.com Chemistry in Korea Leader Award

Overview

Young-Tae Chang is affiliated with Pohang University of Science and Technology in South Korea. The scientist's research spans multiple areas within biochemistry, genetics, molecular biology, and medicine, with significant contributions in related subfields such as molecular biology, immunology, biomedical engineering, physiology, and materials chemistry.

The scientist's work covers a variety of main topics, including:

  • Nanoplatforms for cancer theranostics
  • Advanced biosensing and bioanalysis techniques
  • Adipose tissue and metabolism
  • Molecular sensors and ion detection
  • RNA interference and gene delivery
  • Luminescence and fluorescent materials
  • Immune cell function and interaction

Young-Tae Chang has published extensively in journals such as:

  • Journal of the American Chemical Society
  • Angewandte Chemie International Edition
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Angewandte Chemie
  • Chemosensors

Notable recent publications include:

  • "RNA-Induced Conformational Switching and Clustering of G3BP Drive Stress Granule Assembly by Condensation" (2020) in Cell
  • "Partitioning of cancer therapeutics in nuclear condensates" (2020) in Science
  • "A General Descriptor ΔE Enables the Quantitative Development of Luminescent Materials Based on Photoinduced Electron Transfer" (2020) in Journal of the American Chemical Society
  • "CRISPR-engineered human brown-like adipocytes prevent diet-induced obesity and ameliorate metabolic syndrome in mice" (2020) in Science Translational Medicine
  • "Molecular Mechanism of Viscosity Sensitivity in BODIPY Rotors and Application to Motion-Based Fluorescent Sensors" (2020) in ACS Sensors

Frequent coauthors collaborating with Young-Tae Chang include:

  • Xiao Liu
  • Haw-Young Kwon
  • Sun Hyeok Lee
  • Heewon Cho
  • Nam-Young Kang

The body of research reflects a multidisciplinary approach integrating chemistry, biology, and engineering principles. The scientist's focus on nanoplatforms and biosensing techniques aligns with ongoing developments in biomedical research and medical technology. Their work on RNA interference, gene delivery, and immune cell function suggests involvement in understanding cellular mechanisms and their applications in medicine.

Best Publications

  • RNA buffers the phase separation behavior of prion-like RNA binding proteins

    Shovamayee Maharana;Jie Wang;Dimitrios K. Papadopoulos;Dimitrios K. Papadopoulos;Doris Richter

  • Intracellular glutathione detection using MnO2-nanosheet-modified upconversion nanoparticles

    Renren Deng;Xiaoji Xie;Marc Vendrell;Young-Tae Chang

  • RNA-Induced Conformational Switching and Clustering of G3BP Drive Stress Granule Assembly by Condensation

    Jordina Guillén-Boixet;Andrii Kopach;Alex S. Holehouse;Sina Wittmann

  • Discerning the Chemistry in Individual Organelles with Small-Molecule Fluorescent Probes.

    Wang Xu;Zebing Zeng;Jian-Hui Jiang;Young-Tae Chang;Young-Tae Chang

  • Combinatorial Strategies in Fluorescent Probe Development

    Marc Vendrell;Marc Vendrell;Duanting Zhai;Jun Cheng Er;Young-Tae Chang;Young-Tae Chang

  • Development of Targetable Two-Photon Fluorescent Probes to Image Hypochlorous Acid in Mitochondria and Lysosome in Live Cell and Inflamed Mouse Model

    Lin Yuan;Lin Yuan;Lu Wang;Bikram Keshari Agrawalla;Sung-Jin Park

  • Partitioning of Cancer Therapeutics in Nuclear Condensates

    Isaac A. Klein;Isaac A. Klein;Ann Boija;Lena K. Afeyan;Susana Wilson Hawken

  • Expulsion of small molecules in vesicles shed by cancer cells: association with gene expression and chemosensitivity profiles.

    Kerby Shedden;Xue Tao Xie;Parthapratim Chandaroy;Young Tae Chang

  • Selective Visualization of the Endogenous Peroxynitrite in an Inflamed Mouse Model by a Mitochondria-Targetable Two-Photon Ratiometric Fluorescent Probe

    Dan Cheng;Yue Pan;Lu Wang;Zebing Zeng

  • Mitochondria are physiologically maintained at close to 50 °C.

    Dominique Chretien;Paule Benit;Paule Benit;Hyung-Ho Ha;Susanne Keipert

  • Modulation of CD1d-restricted NKT cell responses by using N-acyl variants of α-galactosylceramides

    Karl O. A. Yu;Jin S. Im;Alberto Molano;Yves Dutronc

  • Surface-enhanced Raman scattering in cancer detection and imaging.

    Marc Vendrell;Kaustabh Kumar Maiti;Kevin Dhaliwal;Young-Tae Chang;Young-Tae Chang

  • Nuclear envelope budding enables large ribonucleoprotein particle export during synaptic Wnt signaling

    Sean D. Speese;James A. Ashley;Vahbiz Jokhi;John J. Nunnari

  • Synthesis and application of functionally diverse 2,6,9-trisubstituted purine libraries as CDK inhibitors.

    Young-Tae Chang;Nathanael S Gray;Gustavo R Rosania;Daniel P Sutherlin

  • Anti-HIV activity of olive leaf extract (OLE) and modulation of host cell gene expression by HIV-1 infection and OLE treatment.

    Sylvia Lee-Huang;Li Zhang;Philip Lin Huang;Young Tae Chang

  • Ultrasensitive near-infrared Raman reporters for SERS-based in vivo cancer detection

    Animesh Samanta;Kaustabh Kumar Maiti;Kiat Seng Soh;Xiaojun Liao

  • Piezoelectric Nanoparticle-Assisted Wireless Neuronal Stimulation

    Attilio Marino;Attilio Marino;Satoshi Arai;Yanyan Hou;Edoardo Sinibaldi

  • Intracellular targets of cyclin-dependent kinase inhibitors: identification by affinity chromatography using immobilised inhibitors

    Marie Knockaert;N. Gray;E. Damiens;Y.-T. Chang

  • Chemical Genetics

    Unknown

  • Myoseverin, a microtubule-binding molecule with novel cellular effects

    Gustavo R. Rosania;Young Tae Chang;Omar Perez;Daniel Sutherlin;Daniel Sutherlin

  • RNA-selective, live cell imaging probes for studying nuclear structure and function.

    Qian Li;Yunkyung Kim;Joshua Namm;Amita Kulkarni

Frequent Co-Authors

Sungjin Park
Sungjin Park Inha University
Xiaogang Liu
Xiaogang Liu National University of Singapore
Peter G. Schultz
Peter G. Schultz Scripps Research Institute
Lin Yuan
Lin Yuan Hunan University
Nathanael S. Gray
Nathanael S. Gray Stanford University
Jishan Wu
Jishan Wu National University of Singapore
Steven A. Porcelli
Steven A. Porcelli Albert Einstein College of Medicine
Gurdyal S. Besra
Gurdyal S. Besra University of Birmingham
Michael Givskov
Michael Givskov University of Copenhagen
Seth J. Orlow
Seth J. Orlow New York University

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