Nathanael S. Gray

Research.com Recognitions

• 2026 - Research.com Biology and Biochemistry in United States Leader Award

Overview

Best Publications

• A Next Generation Connectivity Map: L1000 Platform and the First 1,000,000 Profiles.

  Aravind Subramanian;Rajiv Narayan;Steven M. Corsello;Steven M. Corsello;David D. Peck

  3575
  Citations

• Targeting cancer with small molecule kinase inhibitors

  Jianming Zhang;Priscilla L. Yang;Nathanael S. Gray

  3231
  Citations

• Systematic identification of genomic markers of drug sensitivity in cancer cells

  Mathew J. Garnett;Elena J. Edelman;Sonja J. Heidorn;Christopher Greenman;Christopher Greenman

  2736
  Citations

• A Landscape of Pharmacogenomic Interactions in Cancer

  Francesco Iorio;Francesco Iorio;Theo A. Knijnenburg;Theo A. Knijnenburg;Daniel J. Vis;Graham R. Bignell

  2122
  Citations

• An ATP-competitive mammalian target of rapamycin inhibitor reveals rapamycin-resistant functions of mTORC1.

  Carson C. Thoreen;Seong A. Kang;Jae Won Chang;Qingsong Liu

  2033
  Citations

• DEPTOR Is an mTOR Inhibitor Frequently Overexpressed in Multiple Myeloma Cells and Required for Their Survival

  Timothy R. Peterson;Mathieu Laplante;Carson C. Thoreen;Yasemin Sancak

  1636
  Citations

• A unifying model for mTORC1-mediated regulation of mRNA translation

  Carson Thoreen;Lynne Chantranupong;Lynne Chantranupong;Heather R. Keys;Heather R. Keys;Tim Wang

  1554
  Citations

• Rational design of inhibitors that bind to inactive kinase conformations

  Yi Liu;Nathanael S Gray

  1309
  Citations

• A chemical switch for inhibitor-sensitive alleles of any protein kinase

  Anthony C. Bishop;Jeffrey A. Ubersax;Dejah T. Petsch;Dina P. Matheos

  1245
  Citations

• Novel mutant-selective EGFR kinase inhibitors against EGFR T790M

  Wenjun Zhou;Dalia Ercan;Liang Chen;Cai-Hong Yun

  1223
  Citations

• EML4-ALK fusion gene and efficacy of an ALK kinase inhibitor in lung cancer

  Jussi P. Koivunen;Craig Mermel;Kreshnik Zejnullahu;Carly Murphy

  1211
  Citations

• The mTOR-Regulated Phosphoproteome Reveals a Mechanism of mTORC1-Mediated Inhibition of Growth Factor Signaling

  P. P. Hsu;S. A. Kang;J. Rameseder;Y. Zhang

  1203
  Citations

• Exploiting chemical libraries, structure, and genomics in the search for kinase inhibitors.

  Nathanael S. Gray;Lisa Wodicka;Andy-Mark W. H. Thunnissen;Thea C. Norman

  1140
  Citations

• Activating mutations in ALK provide a therapeutic target in neuroblastoma

  Rani E. George;Takaomi Sanda;Megan C. Hanna;Stefan Fröhling

  1008
  Citations

• Systematic Identification of Culture Conditions for Induction and Maintenance of Naive Human Pluripotency

  Thorold W. Theunissen;Benjamin E. Powell;Haoyi Wang;Maya Mitalipova

  958
  Citations

• YY1 Is a Structural Regulator of Enhancer-Promoter Loops

  Abraham S. Weintraub;Charles H. Li;Alicia V. Zamudio;Alla A. Sigova

  903
  Citations

• The promise and peril of chemical probes.

  Cheryl H. Arrowsmith;James E. Audia;Christopher Austin;Jonathan Baell

  883
  Citations

• Targeting transcription regulation in cancer with a covalent CDK7 inhibitor

  Nicholas Kwiatkowski;Tinghu Zhang;Peter B. Rahl;Brian J Abraham

  846
  Citations

• Kinase inhibitors: the road ahead

  Fleur M. Ferguson;Nathanael S. Gray

  826
  Citations

• The dTAG system for immediate and target-specific protein degradation

  Behnam Nabet;Justin M. Roberts;Dennis L. Buckley;Dennis L. Buckley;Joshiawa Paulk;Joshiawa Paulk

  818
  Citations