What is he best known for?
The fields of study he is best known for:
Kevan M. Shokat mainly focuses on Cell biology, Biochemistry, Kinase, Signal transduction and PI3K/AKT/mTOR pathway.
His Cell biology study combines topics in areas such as Chromatin, Cell cycle, Chromosome segregation and Cytokinesis.
His work in Chromatin addresses subjects such as DNA repair, which are connected to disciplines such as Computational biology.
His studies in Kinase integrate themes in fields like Tyrosine kinase, Cell signaling and Drug discovery.
His research integrates issues of Substrate specificity and Phosphorylation in his study of Signal transduction.
His PI3K/AKT/mTOR pathway research includes themes of Autophagy, Cancer research and Protein kinase B.
His most cited work include:
- RAF inhibitors transactivate RAF dimers and ERK signalling in cells with wild-type BRAF (1354 citations)
- A SARS-CoV-2 protein interaction map reveals targets for drug repurposing. (1317 citations)
- IRE1 Signaling Affects Cell Fate During the Unfolded Protein Response (1030 citations)
What are the main themes of his work throughout his whole career to date?
Kevan M. Shokat mainly investigates Kinase, Cell biology, Biochemistry, Cancer research and PI3K/AKT/mTOR pathway.
His Kinase study combines topics from a wide range of disciplines, such as Tyrosine kinase, Signal transduction and Phosphorylation.
Kevan M. Shokat works mostly in the field of Cell biology, limiting it down to topics relating to Small molecule and, in certain cases, Computational biology.
MAP2K7, SH3 domain, Proto-oncogene tyrosine-protein kinase Src, Enzyme and c-Raf are subfields of Biochemistry in which his conducts study.
His Cancer research study integrates concerns from other disciplines, such as Carcinogenesis, Cancer and MAPK/ERK pathway.
Kevan M. Shokat regularly ties together related areas like Protein kinase B in his PI3K/AKT/mTOR pathway studies.
He most often published in these fields:
- Kinase (44.15%)
- Cell biology (39.79%)
- Biochemistry (36.82%)
What were the highlights of his more recent work (between 2015-2021)?
- Kinase (44.15%)
- Cancer research (22.69%)
- Cell biology (39.79%)
In recent papers he was focusing on the following fields of study:
His main research concerns Kinase, Cancer research, Cell biology, Biochemistry and PI3K/AKT/mTOR pathway.
Kevan M. Shokat combines subjects such as Signal transduction and Phosphorylation with his study of Kinase.
Kevan M. Shokat has included themes like Carcinogenesis, Cancer, Adenocarcinoma, Apoptosis and Kinome in his Cancer research study.
His work in Cell biology tackles topics such as Receptor which are related to areas like Binding site.
TOR Serine-Threonine Kinases is closely connected to Drug resistance in his research, which is encompassed under the umbrella topic of PI3K/AKT/mTOR pathway.
As part of the same scientific family, Kevan M. Shokat usually focuses on TOR Serine-Threonine Kinases, concentrating on Drug discovery and intersecting with Computational biology.
Between 2015 and 2021, his most popular works were:
- A SARS-CoV-2 protein interaction map reveals targets for drug repurposing. (1317 citations)
- Drugging the 'undruggable' cancer targets (270 citations)
- The Global Phosphorylation Landscape of SARS-CoV-2 Infection. (231 citations)
In his most recent research, the most cited papers focused on:
The scientist’s investigation covers issues in Kinase, Cancer research, Biochemistry, PI3K/AKT/mTOR pathway and Phosphorylation.
His Kinase research is under the purview of Cell biology.
His research in Cell biology intersects with topics in Triphosphatase and Functional genomics.
His Enzyme and Pyrazolopyrimidine study, which is part of a larger body of work in Biochemistry, is frequently linked to P-TEFb, RNA polymerase II holoenzyme and Transcription factor II D, bridging the gap between disciplines.
Within one scientific family, Kevan M. Shokat focuses on topics pertaining to Protein kinase B under PI3K/AKT/mTOR pathway, and may sometimes address concerns connected to Glioma and Cell signaling.
As a member of one scientific family, Kevan M. Shokat mostly works in the field of Phosphorylation, focusing on Cyclin-dependent kinase and, on occasion, Cyclin D1, Cyclin-dependent kinase 4 and Tyrosine kinase.
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