Davide Ruggero

Overview

Best Publications

• A SARS-CoV-2 protein interaction map reveals targets for drug repurposing.

  David E. Gordon;Gwendolyn M. Jang;Mehdi Bouhaddou;Jiewei Xu

  5396
  Citations

• VEGFR1-positive haematopoietic bone marrow progenitors initiate the pre-metastatic niche

  Rosandra N. Kaplan;Rebecca D. Riba;Stergios Zacharoulis;Anna H. Bramley

  3735
  Citations

• The translational landscape of mTOR signalling steers cancer initiation and metastasis

  Andrew C. Hsieh;Yi Liu;Merritt P. Edlind;Nicholas T. Ingolia

  1434
  Citations

• Active-site inhibitors of mTOR target rapamycin-resistant outputs of mTORC1 and mTORC2.

  Morris E Feldman;Beth Apsel;Aino Uotila;Robbie Loewith

  1336
  Citations

• Does the ribosome translate cancer

  Davide Ruggero;Pier Paolo Pandolfi

  1285
  Citations

• PML is essential for multiple apoptotic pathways.

  Zhu-Gang Wang;Davide Ruggero;Simona Ronchetti;Sue Zhong

  745
  Citations

• The translation factor eIF-4E promotes tumor formation and cooperates with c-Myc in lymphomagenesis.

  Davide Ruggero;Davide Ruggero;Lorenzo Montanaro;Li Ma;Wei Xu

  710
  Citations

• IRE1α Cleaves Select microRNAs During ER Stress to Derepress Translation of Proapoptotic Caspase-2

  John-Paul Upton;Likun Wang;Dan Han;Eric S. Wang

  689
  Citations

• Autism-related deficits via dysregulated eIF4E-dependent translational control

  Christos G. Gkogkas;Arkady Khoutorsky;Israeli Ran;Emmanouil Rampakakis

  600
  Citations

• Genetic dissection of the oncogenic mTOR pathway reveals druggable addiction to translational control via 4EBP-eIF4E.

  Andrew C. Hsieh;Maria Costa;Ornella Zollo;Cole Davis

  528
  Citations

• Dyskeratosis congenita and cancer in mice deficient in ribosomal RNA modification

  Davide Ruggero;Silvia Grisendi;Francesco Piazza;Eduardo Rego;Eduardo Rego

  516
  Citations

• Suppression of Myc oncogenic activity by ribosomal protein haploinsufficiency.

  Maria Barna;Aya Pusic;Ornella Zollo;Maria Costa

  496
  Citations

• Impaired Control of IRES-Mediated Translation in X-Linked Dyskeratosis Congenita

  Andrew Yoon;Guang Peng;Yves Brandenburg;Ornella Zollo

  457
  Citations

• ER stress–mediated autophagy promotes Myc-dependent transformation and tumor growth

  Lori S. Hart;John T. Cunningham;Tatini Datta;Souvik Dey

  410
  Citations

• Exaggerated translation causes synaptic and behavioural aberrations associated with autism

  Emanuela Santini;Thu N. Huynh;Andrew F. MacAskill;Adam G. Carter

  393
  Citations

• Targeting the eIF4F translation initiation complex: a critical nexus for cancer development.

  Jerry Pelletier;Jeremy Graff;Davide Ruggero;Nahum Sonenberg

  371
  Citations

• Translational Control in Cancer Etiology

  Davide Ruggero

  353
  Citations

• Differential Requirements for eIF4E Dose in Normal Development and Cancer

  Morgan L. Truitt;Crystal S. Conn;Zhen Shi;Xiaming Pang

  345
  Citations

• rRNA pseudouridylation defects affect ribosomal ligand binding and translational fidelity from yeast to human cells.

  Karen Jack;Cristian Bellodi;Dori M. Landry;Rachel O. Niederer

  337
  Citations

• Translational Control in Cancer

  Nathaniel Robichaud;Nahum Sonenberg;Davide Ruggero;Robert J. Schneider

  225
  Citations