D-Index & Metrics Best Publications

D-Index & Metrics

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Neuroscience D-index 64 Citations 16,063 137 World Ranking 1138 National Ranking 581
Biology and Biochemistry D-index 73 Citations 17,119 132 World Ranking 2497 National Ranking 1337

Research.com Recognitions

Awards & Achievements

2013 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Enzyme
  • Neuron

His primary scientific interests are in Neuroscience, Synaptic plasticity, Cell biology, Long-term potentiation and Superoxide. His work deals with themes such as P70-S6 Kinase 1 and Fragile X syndrome, which intersect with Neuroscience. His studies in Synaptic plasticity integrate themes in fields like PI3K/AKT/mTOR pathway, Signal transduction, Soma and Protein biosynthesis.

The various areas that Eric Klann examines in his Cell biology study include Hippocampal formation, Glutamate receptor, Metabotropic glutamate receptor and Long-term depression. His studies deal with areas such as Reactive oxygen species, Hippocampus, Cell signaling and Protein kinase A as well as Long-term potentiation. His Superoxide study deals with NADPH oxidase intersecting with Oxidase test, Nitric oxide synthase, Cerebral cortex and Membrane protein.

His most cited work include:

  • mTOR signaling: at the crossroads of plasticity, memory and disease. (782 citations)
  • Translational control of long-lasting synaptic plasticity and memory. (682 citations)
  • Extinction-reconsolidation boundaries: key to persistent attenuation of fear memories (672 citations)

What are the main themes of his work throughout his whole career to date?

Eric Klann spends much of his time researching Neuroscience, Synaptic plasticity, Cell biology, Long-term potentiation and Translation. His study ties his expertise on Fragile X syndrome together with the subject of Neuroscience. His study in Synaptic plasticity is interdisciplinary in nature, drawing from both Endocrinology and Signal transduction.

His biological study deals with issues like Hippocampal formation, which deal with fields such as Extracellular. The study incorporates disciplines such as Protein kinase A, NMDA receptor, Reactive oxygen species, PI3K/AKT/mTOR pathway and Superoxide in addition to Long-term potentiation. His Translation study combines topics from a wide range of disciplines, such as Regulation of gene expression and Protein biosynthesis.

He most often published in these fields:

  • Neuroscience (63.71%)
  • Synaptic plasticity (42.62%)
  • Cell biology (36.71%)

What were the highlights of his more recent work (between 2017-2021)?

  • Neuroscience (63.71%)
  • Protein biosynthesis (16.46%)
  • Translation (18.14%)

In recent papers he was focusing on the following fields of study:

Eric Klann mainly focuses on Neuroscience, Protein biosynthesis, Translation, Amygdala and Cell biology. His Neuroscience research incorporates elements of Autism spectrum disorder, P70-S6 Kinase 1 and Phosphorylation. His Protein biosynthesis research also works with subjects such as

  • Fragile X syndrome, which have a strong connection to Phenotype, Oncology, Internal medicine and Metabotropic glutamate receptor,
  • Proteome which is related to area like Hippocampus, Neuropathology, Function, Pathology and Memory impairment.

His research integrates issues of Synaptic plasticity and RNA in his study of Translation. His Synaptic plasticity study integrates concerns from other disciplines, such as Cancer, Internalization and Memory consolidation. Eric Klann interconnects Long-term potentiation, Neural development and Cell growth in the investigation of issues within Cell biology.

Between 2017 and 2021, his most popular works were:

  • Isoform-selective phosphoinositide 3-kinase inhibition ameliorates a broad range of fragile X syndrome-associated deficits in a mouse model. (19 citations)
  • Axon TRAP reveals learning-associated alterations in cortical axonal mRNAs in the lateral amgydala. (13 citations)
  • Altered steady state and activity-dependent de novo protein expression in fragile X syndrome (13 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • Neuron

His main research concerns Neuroscience, Protein biosynthesis, Amygdala, Phenotype and Fragile X syndrome. Eric Klann combines subjects such as Synaptic plasticity and Translation with his study of Neuroscience. His Protein biosynthesis research integrates issues from eIF2, Cell growth, EIF2S3 and Cell biology.

Eric Klann has researched Amygdala in several fields, including P70-S6 Kinase 1, Memory consolidation, Eukaryotic initiation factor and Phosphorylation. His biological study spans a wide range of topics, including Internal medicine, Blood based biomarkers, Target engagement and Oncology. His work carried out in the field of Fragile X syndrome brings together such families of science as Biomarker, Clinical trial and MMP9.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

mTOR signaling: at the crossroads of plasticity, memory and disease.

Charles A. Hoeffer;Eric Klann.
Trends in Neurosciences (2010)

989 Citations

Extinction-reconsolidation boundaries: key to persistent attenuation of fear memories

Marie H. Monfils;Kiriana K. Cowansage;Eric Klann;Joseph E. Ledoux.
Science (2009)

930 Citations

Translational control of long-lasting synaptic plasticity and memory.

Mauro Costa-Mattioli;Wayne S. Sossin;Eric Klann;Nahum Sonenberg.
Neuron (2009)

846 Citations

Glutamate-induced neuron death requires mitochondrial calcium uptake.

Amy K. Stout;Heather M. Raphael;Beatriz I. Kanterewicz;Eric Klann.
Nature Neuroscience (1998)

728 Citations

Persistent Activation of ERK Contributes to Glutamate-induced Oxidative Toxicity in a Neuronal Cell Line and Primary Cortical Neuron Cultures

Madalina Stanciu;Ying Wang;Ruth Kentor;Nancy Burke.
Journal of Biological Chemistry (2000)

623 Citations

Activation of the Phosphoinositide 3-Kinase-Akt-Mammalian Target of Rapamycin Signaling Pathway Is Required for Metabotropic Glutamate Receptor-Dependent Long-Term Depression

Lingfei Hou;Eric Klann.
The Journal of Neuroscience (2004)

566 Citations

Dysregulation of mTOR Signaling in Fragile X Syndrome

Ali Sharma;Charles A. Hoeffer;Yukihiro Takayasu;Yukihiro Takayasu;Takahiro Miyawaki;Takahiro Miyawaki.
The Journal of Neuroscience (2010)

515 Citations

Dynamic Translational and Proteasomal Regulation of Fragile X Mental Retardation Protein Controls mGluR-Dependent Long-Term Depression

Lingfei Hou;Marcia D. Antion;Daoying Hu;Corinne M. Spencer.
Neuron (2006)

473 Citations

Biochemical mechanisms for translational regulation in synaptic plasticity

Eric Klann;Thomas E. Dever.
Nature Reviews Neuroscience (2004)

453 Citations

Reactive oxygen species and synaptic plasticity in the aging hippocampus.

Faridis Serrano;Eric Klann.
Ageing Research Reviews (2004)

451 Citations

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