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Neuroscience

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90
Citations
27959
World Ranking
1115
National Ranking
577

Biology and Biochemistry

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89
Citations
26775
World Ranking
2580
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Research.com Recognitions

  • 2013 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Eric Klann is affiliated with New York University in the United States. Their research principally covers Biochemistry, Genetics and Molecular Biology, with additional focus in Neuroscience. Within these main fields, they have contributed extensively to subfields such as Molecular Biology, Cellular and Molecular Neuroscience, Genetics, Cognitive Neuroscience, and Cell Biology.

The scientist's work addresses a range of topics including Genetics and Neurodevelopmental Disorders, Autism Spectrum Disorder Research, Receptor Mechanisms and Signaling, Neuroscience and Neuropharmacology Research, RNA regulation and disease, RNA and protein synthesis mechanisms, and RNA modifications and cancer.

Among Eric Klann's recent scholarly publications are:

  • Correction of eIF2-dependent defects in brain protein synthesis, synaptic plasticity, and memory in mouse models of Alzheimer's disease (2021, Science Signaling)
  • Astrocytes derived from ASD individuals alter behavior and destabilize neuronal activity through aberrant Ca2+ signaling (2022, Molecular Psychiatry)
  • Cell-type-specific drug-inducible protein synthesis inhibition demonstrates that memory consolidation requires rapid neuronal translation (2020, Nature Neuroscience)
  • Amygdala inhibitory neurons as loci for translation in emotional memories (2020, Nature)
  • Cell-type-specific profiling of human cellular models of fragile X syndrome reveal PI3K-dependent defects in translation and neurogenesis (2021, Cell Reports)

Eric Klann frequently collaborates with other researchers, including:

  • Maurício M. Oliveira
  • Francesco Longo
  • Prerana Shrestha
  • Maggie Mamcarz
  • Sameer Aryal

Their publications have appeared in venues such as bioRxiv (Cold Spring Harbor Laboratory), Proceedings of the National Academy of Sciences, Molecular Psychiatry, Cell Reports, and Communications Biology.

In 2013, Eric Klann was recognized as a Fellow of the American Association for the Advancement of Science (AAAS).

Best Publications

  • mTOR signaling: at the crossroads of plasticity, memory and disease.

    Charles A. Hoeffer;Eric Klann

  • Extinction-reconsolidation boundaries: key to persistent attenuation of fear memories

    Marie H. Monfils;Kiriana K. Cowansage;Eric Klann;Joseph E. Ledoux

  • Translational control of long-lasting synaptic plasticity and memory.

    Mauro Costa-Mattioli;Wayne S. Sossin;Eric Klann;Nahum Sonenberg

  • Glutamate-induced neuron death requires mitochondrial calcium uptake.

    Amy K. Stout;Heather M. Raphael;Beatriz I. Kanterewicz;Eric Klann

  • Reactive oxygen species in the regulation of synaptic plasticity and memory.

    Cynthia A. Massaad;Eric Klann

  • Persistent Activation of ERK Contributes to Glutamate-induced Oxidative Toxicity in a Neuronal Cell Line and Primary Cortical Neuron Cultures

    Madalina Stanciu;Ying Wang;Ruth Kentor;Nancy Burke

  • Activation of the Phosphoinositide 3-Kinase-Akt-Mammalian Target of Rapamycin Signaling Pathway Is Required for Metabotropic Glutamate Receptor-Dependent Long-Term Depression

    Lingfei Hou;Eric Klann

  • Dysregulation of mTOR Signaling in Fragile X Syndrome

    Ali Sharma;Charles A. Hoeffer;Yukihiro Takayasu;Yukihiro Takayasu;Takahiro Miyawaki;Takahiro Miyawaki

  • Suppression of eIF2α kinases alleviates Alzheimer's disease–related plasticity and memory deficits

    Tao Ma;Mimi A Trinh;Alyse J Wexler;Clarisse Bourbon;Clarisse Bourbon

  • Dynamic Translational and Proteasomal Regulation of Fragile X Mental Retardation Protein Controls mGluR-Dependent Long-Term Depression

    Lingfei Hou;Marcia D. Antion;Daoying Hu;Corinne M. Spencer

  • The translation of translational control by FMRP: therapeutic targets for FXS

    Jennifer C Darnell;Eric Klann

  • Reactive oxygen species and synaptic plasticity in the aging hippocampus.

    Faridis Serrano;Eric Klann

  • Biochemical mechanisms for translational regulation in synaptic plasticity

    Eric Klann;Thomas E. Dever

  • Making synaptic plasticity and memory last: mechanisms of translational regulation

    Joel D. Richter;Eric Klann

  • Exaggerated translation causes synaptic and behavioural aberrations associated with autism

    Emanuela Santini;Thu N. Huynh;Andrew F. MacAskill;Adam G. Carter

  • Local RNA translation at the synapse and in disease.

    Liqun Liu-Yesucevitz;Gary J. Bassell;Aaron D. Gitler;Anne C. Hart

  • The translation repressor 4E-BP2 is critical for eIF4F complex formation, synaptic plasticity, and memory in the hippocampus.

    Jessica L. Banko;Francis Poulin;Lingfei Hou;Christine T. DeMaria

  • Sources and Targets of Reactive Oxygen Species in Synaptic Plasticity and Memory

    Kenneth T. Kishida;Eric Klann;Eric Klann

  • Dysregulation and restoration of translational homeostasis in fragile X syndrome.

    Joel D. Richter;Gary J. Bassell;Eric Klann

  • Genetic Removal of p70 S6 Kinase 1 Corrects Molecular, Synaptic, and Behavioral Phenotypes in Fragile X Syndrome Mice

    Aditi Bhattacharya;Hanoch Kaphzan;Amanda C. Alvarez-Dieppa;Jaclyn P. Murphy

Frequent Co-Authors

Joseph E. LeDoux
Joseph E. LeDoux New York University
J. David Sweatt
J. David Sweatt University of Alabama at Birmingham
Philippe Pierre
Philippe Pierre Aix-Marseille University
German Barrionuevo
German Barrionuevo University of Pittsburgh
Gary J. Bassell
Gary J. Bassell Emory University
Nahum Sonenberg
Nahum Sonenberg McGill University
Moses V. Chao
Moses V. Chao New York University
Joel D. Richter
Joel D. Richter University of Massachusetts Chan Medical School
Thomas A. Neubert
Thomas A. Neubert New York University
Peter V. Nguyen
Peter V. Nguyen University of Alberta

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