What is he best known for?
The fields of study he is best known for:
His primary scientific interests are in Biochemistry, Protein structure, Cell biology, Kinase and Phosphorylation.
His study involves Enzyme, Hydrolase, Binding site, Transferase and Serratia marcescens, a branch of Biochemistry.
His Enzyme study integrates concerns from other disciplines, such as Chitin deacetylase and Peptide sequence.
Daan M. F. van Aalten has included themes like Hydrophobin, Plasma protein binding and Scaffold protein in his Protein structure study.
His research in the fields of Protein kinase A overlaps with other disciplines such as PINK1.
Daan M. F. van Aalten interconnects Signal transduction and Ubiquitin ligase in the investigation of issues within Phosphorylation.
His most cited work include:
- PDK1, the master regulator of AGC kinase signal transduction. (654 citations)
- The Non-catalytic Chitin-binding Protein CBP21 from Serratia marcescens Is Essential for Chitin Degradation (272 citations)
- High-Resolution Structure of the Pleckstrin Homology Domain of Protein Kinase B/Akt Bound to Phosphatidylinositol (3,4,5)-Trisphosphate (243 citations)
What are the main themes of his work throughout his whole career to date?
His scientific interests lie mostly in Biochemistry, Enzyme, Transferase, Stereochemistry and Protein structure.
In his research, Cell wall is intimately related to Aspergillus fumigatus, which falls under the overarching field of Biochemistry.
His Enzyme research includes themes of Antifungal drug and Saccharomyces cerevisiae, Yeast.
His Transferase research is multidisciplinary, incorporating elements of Genetics, Glycosylation, Serine, Tetratricopeptide and Cell biology.
His work deals with themes such as Cyclic peptide, Peptide, Substrate and Residue, which intersect with Stereochemistry.
His Protein structure study which covers Plasma protein binding that intersects with Protein phosphorylation.
He most often published in these fields:
- Biochemistry (61.05%)
- Enzyme (27.37%)
- Transferase (24.74%)
What were the highlights of his more recent work (between 2015-2021)?
- Biochemistry (61.05%)
- Transferase (24.74%)
- Enzyme (27.37%)
In recent papers he was focusing on the following fields of study:
His primary areas of study are Biochemistry, Transferase, Enzyme, Cell biology and Glycosylation.
He frequently studies issues relating to Aspergillus fumigatus and Biochemistry.
His Transferase research integrates issues from Genetics, Intellectual disability, Serine, Tetratricopeptide and Glycosyltransferase.
His Enzyme research incorporates themes from Protein structure, Aspartic acid, Antifungal drug and Mutagenesis.
He has researched Cell biology in several fields, including Phenotype, Drosophila melanogaster, Glutamine and Point mutation.
His research integrates issues of Acceptor, Biophysics, Proteolysis, Stereochemistry and Substrate in his study of Glycosylation.
Between 2015 and 2021, his most popular works were:
- Glucose and glutamine fuel protein O-GlcNAcylation to control T cell self-renewal and malignancy (159 citations)
- Activity-based E3 ligase profiling uncovers an E3 ligase with esterification activity (75 citations)
- Structure of PINK1 and mechanisms of Parkinson's disease-associated mutations (42 citations)
In his most recent research, the most cited papers focused on:
Daan M. F. van Aalten mainly investigates Biochemistry, Transferase, Serine, Gene and Cell biology.
His work in IL-2 receptor, Uridine diphosphate N-acetylglucosamine, CD28, Glutamine transport and ZAP70 are all subfields of Biochemistry research.
His study on Transferase is covered under Enzyme.
In his study, Peptide, Thio-, Glycosyltransferase and HeLa is inextricably linked to Cysteine, which falls within the broad field of Serine.
His work on Mutation as part of his general Gene study is frequently connected to Parkinson's disease and In patient, thereby bridging the divide between different branches of science.
His Cell biology research includes elements of Model organism, Hox gene, Drosophila melanogaster and Mutant, Homeotic gene.
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