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Medicine

D-Index
101
Citations
34433
World Ranking
8040
National Ranking
4173

Research.com Recognitions

  • Member of the Association of American Physicians
  • Member of the Association of American Physicians

Overview

Stephen J. Meltzer is affiliated with Johns Hopkins University School of Medicine in the United States, with a research focus spanning medicine and biochemistry, genetics, and molecular biology. Their work includes significant contributions to surgery, molecular biology, pulmonary and respiratory medicine, cancer research, and oncology.

The scientist's primary research topics emphasize esophageal cancer research and treatment, gastric cancer management and outcomes, epigenetics and DNA methylation, esophageal and gastrointestinal pathology, RNA modifications and cancer, microRNA in disease regulation, and cancer-related molecular mechanisms research.

Stephen J. Meltzer has published extensively in several prominent venues, including:

  • Gastroenterology
  • The American Journal of Gastroenterology
  • UNC Libraries
  • Molecular Cancer
  • Nature Communications

Their recent publications highlight various aspects of cancer biology and molecular pathways:

  • A novel protein AXIN1-295aa encoded by circAXIN1 activates the Wnt/β-catenin signaling pathway to promote gastric cancer progression, 2021, Molecular Cancer
  • Interplay and cooperation between SREBF1 and master transcription factors regulate lipid metabolism and tumor-promoting pathways in squamous cancer, 2021, Nature Communications
  • Risk Factors for Progression of Barrett's Esophagus to High Grade Dysplasia and Esophageal Adenocarcinoma, 2020, Scientific Reports
  • Vimentin binds to a novel tumor suppressor protein, GSPT1-238aa, encoded by circGSPT1 with a selective encoding priority to halt autophagy in gastric carcinoma, 2022, Cancer Letters
  • miRNA-192 and -215 activate Wnt/β-catenin signaling pathway in gastric cancer via APC, 2020, Journal of Cellular Physiology

Stephen J. Meltzer frequently collaborates with a range of researchers, including Yulan Cheng, Andrew Kalra, Sarah Laun, Daniel Lunz, and Lisa Kann.

The scientist has been recognized as a member of the Association of American Physicians, reflecting a professional standing within the medical community.

Best Publications

  • A National Cancer Institute Workshop on Microsatellite Instability for Cancer Detection and Familial Predisposition: Development of International Criteria for the Determination of Microsatellite Instability in Colorectal Cancer

    C. Richard Boland;Stephen N. Thibodeau;Stanley R. Hamilton;David Sidransky

  • 6-Mercaptopurine in the management of inflammatory bowel disease: short- and long-term toxicity.

    Daniel H. Present;Stephen J. Meltzer;Michael P. Krumholz;Anita Wolke

  • Increased Expression of Inducible Nitric Oxide Synthase and Cyclooxygenase-2 in Barrett's Esophagus and Associated Adenocarcinomas

    Keith T. Wilson;Sidong Fu;Kalathur S. Ramanujam;Stephen J. Meltzer

  • Analysis of adenomatous polyposis coli promoter hypermethylation in human cancer.

    Manel Esteller;Andrew Sparks;Minoru Toyota;Montserrat Sanchez-Cespedes

  • MicroRNAs and epigenetics.

    Fumiaki Sato;Soken Tsuchiya;Stephen J. Meltzer;Kazuharu Shimizu

  • Microsatellite instability in the insulin–like growth factor II receptor gene in gastrointestinal tumours

    R. F. Souza;R. Appel;J. Yin;S. Wang

  • Increased expression and cellular localization of inducible nitric oxide synthase and cyclooxygenase 2 in Helicobacter pylori gastritis.

    Sidong Fu;Kalathur S. Ramanujam;Annie Wong;George T. Fantry

  • Molecular evolution of the metaplasia-dysplasia-adenocarcinoma sequence in the esophagus.

    Janusz A. Jankowski;Nick A. Wright;Stephen J. Meltzer;George Triadafilopoulos

  • E-Cadherin Gene Promoter Hypermethylation in Primary Human Gastric Carcinomas

    Gen Tamura;Jing Yin;Suna Wang;A. S. Fleisher

  • Hypermethylation of the hMLH1 Gene Promoter in Human Gastric Cancers with Microsatellite Instability

    A. Steven Fleisher;Manel Esteller;Suna Wang;Gen Tamura

  • Consensus Statements for Management of Barrett's Dysplasia and Early-Stage Esophageal Adenocarcinoma, Based on a Delphi Process

    Cathy Bennett;Nimish Vakil;Jacques Bergman;Rebecca Harrison

  • Hypermethylated APC DNA in Plasma and Prognosis of Patients With Esophageal Adenocarcinoma

    Kazuyuki Kawakami;Jan Brabender;Reginald V. Lord;Susan Groshen

  • A DNA methylation fingerprint of 1628 human samples

    Augustin F. Fernandez;Yassen Assenov;Jose Ignacio Martin-Subero;Balazs Balint

  • PTEN1 is frequently mutated in primary endometrial carcinomas

    Dehe Kong;Dehe Kong;Akihiko Suzuki;Tong Tong Zou;Akira Sakurada;Akira Sakurada

  • Pharmacologic unmasking of epigenetically silenced tumor suppressor genes in esophageal squamous cell carcinoma.

    Keishi Yamashita;Sunil Upadhyay;Motonobu Osada;Mohammad O Hoque

  • Comparative genomic analysis of esophageal adenocarcinoma and squamous cell carcinoma

    Nishant Agrawal;Yuchen Jiao;Chetan Bettegowda;Susan M. Hutfless

  • Identification of microRNAs associated with ileal and colonic Crohn's disease

    Feng Wu;Simin Zhang;Themistocles Dassopoulos;Mary L. Harris

  • The miR-106b-25 Polycistron, Activated by Genomic Amplification, Functions as an Oncogene by Suppressing p21 and Bim

    Takatsugu Kan;Fumiaki Sato;Tetsuo Ito;Nobutoshi Matsumura

  • MicroRNA-21 is overexpressed in human cholangiocarcinoma and regulates programmed cell death 4 and tissue inhibitor of metalloproteinase 3

    Florin M. Selaru;Alexandru V. Olaru;Takatsugu Kan;Stefan David

  • Application of cDNA microarrays to generate a molecular taxonomy capable of distinguishing between colon cancer and normal colon.

    Tong Tong Zou;Florin M. Selaru;Yan Xu;Valentina Shustova

Frequent Co-Authors

Barbara A. Leggett
Barbara A. Leggett University of Queensland
Joanne P. Young
Joanne P. Young University of Adelaide
Keith T. Wilson
Keith T. Wilson Vanderbilt University Medical Center
Yutaka Shimada
Yutaka Shimada Kyoto University
Elizabeth A. Montgomery
Elizabeth A. Montgomery University of Miami
Stephen P. James
Stephen P. James National Institutes of Health
Kenneth K. Wang
Kenneth K. Wang Mayo Clinic
Marcia I. Canto
Marcia I. Canto Johns Hopkins University
Jeremy R. Jass
Jeremy R. Jass Imperial College London
Manel Esteller
Manel Esteller Josep Carreras Leukaemia Research Institute

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