D-Index & Metrics Best Publications
Research.com 2022 Best Scientist Award Badge

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Medicine D-index 151 Citations 103,700 545 World Ranking 414 National Ranking 251
Best Scientists D-index 160 Citations 116,412 791 World Ranking 833 National Ranking 537

Research.com Recognitions

Awards & Achievements

2022 - Research.com Best Scientist Award

Overview

What is he best known for?

The fields of study he is best known for:

  • Cancer
  • Gene
  • Internal medicine

His primary areas of study are Cancer research, Pathology, Cancer, Tumor suppressor gene and Gene. His Cancer research research is multidisciplinary, incorporating elements of Methylation, DNA methylation, Carcinogenesis, Point mutation and Prostate cancer. He has researched Carcinogenesis in several fields, including Cell cycle and Haematopoiesis.

His Pathology research integrates issues from Head and neck squamous-cell carcinoma, Head and neck cancer, Internal medicine and Loss of heterozygosity. His Cancer research incorporates themes from Lung cancer and Oncology. His Tumor suppressor gene study deals with Locus intersecting with Chromosome 9.

His most cited work include:

  • p53 mutations in human cancers (6981 citations)
  • A National Cancer Institute Workshop on Microsatellite Instability for Cancer Detection and Familial Predisposition: Development of International Criteria for the Determination of Microsatellite Instability in Colorectal Cancer (3519 citations)
  • Participation of p53 Protein in the Cellular Response to DNA Damage (3461 citations)

What are the main themes of his work throughout his whole career to date?

David Sidransky mainly investigates Cancer research, Cancer, Pathology, Internal medicine and DNA methylation. His Cancer research study which covers Carcinogenesis that intersects with Gene silencing. David Sidransky works mostly in the field of Cancer, limiting it down to topics relating to Mutation and, in certain cases, Mitochondrial DNA, as a part of the same area of interest.

His Pathology study incorporates themes from Primary tumor, Loss of heterozygosity and Adenocarcinoma. His Internal medicine study combines topics in areas such as Endocrinology and Oncology. His research in DNA methylation intersects with topics in Molecular biology, Methylation and Prostate cancer.

He most often published in these fields:

  • Cancer research (48.23%)
  • Cancer (37.97%)
  • Pathology (30.00%)

What were the highlights of his more recent work (between 2016-2021)?

  • Cancer research (48.23%)
  • Cancer (37.97%)
  • Head and neck squamous-cell carcinoma (15.82%)

In recent papers he was focusing on the following fields of study:

His primary areas of investigation include Cancer research, Cancer, Head and neck squamous-cell carcinoma, Oncology and Internal medicine. His studies in Cancer research integrate themes in fields like Cell, Cell growth, Downregulation and upregulation, microRNA and Kinase. His Cancer study combines topics from a wide range of disciplines, such as Epigenetics, Alternative splicing and Central nervous system.

As part of one scientific family, David Sidransky deals mainly with the area of Epigenetics, narrowing it down to issues related to the DNA methylation, and often Pathology, Germline, Carcinoma and Early detection. His Head and neck squamous-cell carcinoma research is multidisciplinary, incorporating perspectives in Metastasis, Notch signaling pathway, Mitochondrial DNA and Tissue microarray. His Oncology research includes themes of KRAS and Proportional hazards model.

Between 2016 and 2021, his most popular works were:

  • Correction: Corrigendum: A dual specificity kinase, DYRK1A, as a potential therapeutic target for head and neck squamous cell carcinoma (158 citations)
  • Patient-derived xenografts effectively capture responses to oncology therapy in a heterogeneous cohort of patients with solid tumors (105 citations)
  • Bifunctional immune checkpoint-targeted antibody-ligand traps that simultaneously disable TGFβ enhance the efficacy of cancer immunotherapy (98 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Cancer
  • Internal medicine

David Sidransky mostly deals with Cancer research, Cancer, Head and neck squamous-cell carcinoma, Lung cancer and Internal medicine. His Cancer research research focuses on Tumor microenvironment in particular. David Sidransky specializes in Cancer, namely Carcinogenesis.

David Sidransky has included themes like Tyrosine kinase, DNA methylation, Bioinformatics and ALK Gene Rearrangement in his Lung cancer study. His work deals with themes such as DYRK1A, Oncology and Pathology, which intersect with Internal medicine. David Sidransky combines subjects such as Sanger sequencing and Vaginal flora with his study of Pathology.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

p53 mutations in human cancers

Monica Hollstein;David Sidransky;Bert Vogelstein;Curtis C. Harris.
Science (1991)

10340 Citations

Participation of p53 Protein in the Cellular Response to DNA Damage

Michael B. Kastan;Onyinye Onyekwere;David Sidransky;Bert Vogelstein.
Cancer Research (1991)

5056 Citations

A National Cancer Institute Workshop on Microsatellite Instability for Cancer Detection and Familial Predisposition: Development of International Criteria for the Determination of Microsatellite Instability in Colorectal Cancer

C. Richard Boland;Stephen N. Thibodeau;Stanley R. Hamilton;David Sidransky.
Cancer Research (1998)

3770 Citations

Evidence for a Causal Association Between Human Papillomavirus and a Subset of Head and Neck Cancers

Maura Gillison;Wayne M. Koch;Randolph B. Capone;Michael Spafford.
Journal of the National Cancer Institute (2000)

3397 Citations

5' CpG island methylation is associated with transcriptional silencing of the tumour suppressor p16/CDKN2/MTS1 in human cancers.

Adrian Merlo;James G. Herman;Li Mao;Daniel J. Lee.
Nature Medicine (1995)

2446 Citations

Inactivation of the CDKN2/p16/MTS1 Gene Is Frequently Associated with Aberrant DNA Methylation in All Common Human Cancers

James G. Herman;Adrian Merlo;Li Mao;Rena G. Lapidus.
Cancer Research (1995)

1888 Citations

Exome sequencing of head and neck squamous cell carcinoma reveals inactivating mutations in NOTCH1

Nishant Agrawal;Mitchell J. Frederick;Curtis R. Pickering;Chetan Bettegowda.
Science (2011)

1684 Citations

Genetic progression model for head and neck cancer: Implications for field cancerization

Joseph Califano;Peter Van Der Riet;William Westra;Homaira Nawroz.
Cancer Research (1996)

1675 Citations

Head and neck cancer.

Arlene Forastiere;Wayne Koch;Andrew Trotti;David Sidransky.
The New England Journal of Medicine (2001)

1605 Citations

Detection of Aberrant Promoter Hypermethylation of Tumor Suppressor Genes in Serum DNA from Non-Small Cell Lung Cancer Patients

Manel Esteller;Montserrat Sanchez-Cespedes;Rafael Rosell;David Sidransky.
Cancer Research (1999)

1200 Citations

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