World's Best Scientists 2026 revealed!

D-Index & Metrics

Medicine

D-Index
94
Citations
42037
World Ranking
10315
National Ranking
5305

Overview

Wayne M. Koch is affiliated with Johns Hopkins University in the United States and has contributed extensively to the field of medicine, with a focus on otorhinolaryngology, surgery, oncology, molecular biology, and pulmonary and respiratory medicine.

The scientist's research spans multiple topics, including:

  • Head and Neck Cancer Studies
  • Cancer Diagnosis and Treatment
  • Head and Neck Surgical Oncology
  • Lung Cancer Treatments and Mutations
  • Global Health and Surgery
  • Cervical Cancer and HPV Research
  • Salivary Gland Tumors Diagnosis and Treatment

Notable papers authored or co-authored by the scientist include:

  • Global Burden of Head and Neck Cancer: Economic Consequences, Health, and the Role of Surgery, 2020, Otolaryngology
  • Transoral robotic surgical resection followed by randomization to low- or standard-dose IMRT in resectable p16+ locally advanced oropharynx cancer: A trial of the ECOG-ACRIN Cancer Research Group (E3311)., 2020, Journal of Clinical Oncology
  • HPV E2, E4, E5 drive alternative carcinogenic pathways in HPV positive cancers, 2020, Oncogene
  • Comparison of next generation sequencing, droplet digital PCR, and quantitative real-time PCR for the earlier detection and quantification of HPV in HPV-positive oropharyngeal cancer, 2022, Oral Oncology
  • A novel surgeon credentialing and quality assurance process using transoral surgery for oropharyngeal cancer in ECOG-ACRIN Cancer Research Group Trial E3311, 2020, Oral Oncology

Frequent co-authors in the scientist's publications include:

  • Carole Fakhry
  • Harry Quon
  • Christine G. Gourin
  • Robert L. Ferris
  • Gregory S. Weinstein

Publications are commonly found in several key venues, such as:

  • Journal of Clinical Oncology
  • The Laryngoscope
  • Otolaryngology
  • Oral Oncology
  • Cancers

Wayne M. Koch's research work predominantly focuses on advancing understanding and treatment of head and neck cancers, especially exploring surgical approaches and diagnostic methodologies. Their studies include investigations into HPV-related carcinogenic pathways as well as clinical trials assessing therapeutic strategies for oropharyngeal cancer.

The scientist's body of work reflects a multidisciplinary approach combining clinical oncology, surgical techniques, molecular biology, and epidemiological aspects of cancer. This has contributed data addressing global health and economic impacts, as well as innovations in surgical credentialing and quality assurance.

Best Publications

  • Evidence for a Causal Association Between Human Papillomavirus and a Subset of Head and Neck Cancers

    Maura Gillison;Wayne M. Koch;Randolph B. Capone;Michael Spafford

  • Case-control study of human papillomavirus and oropharyngeal cancer.

    Aimee R. Kreimer;Raphael Viscidi;Michael Pawlita;Carole Fakhry

  • Exome sequencing of head and neck squamous cell carcinoma reveals inactivating mutations in NOTCH1

    Nishant Agrawal;Mitchell J. Frederick;Curtis R. Pickering;Chetan Bettegowda

  • Genetic progression model for head and neck cancer: Implications for field cancerization

    Joseph Califano;Peter Van Der Riet;William Westra;Homaira Nawroz

  • Head and neck cancer.

    Arlene Forastiere;Wayne Koch;Andrew Trotti;David Sidransky

  • Microsatellite alterations in serum DNA of head and neck cancer patients.

    Homaira Nawroz;Wayne Koch;Philippe Anker;Maurice Stroun

  • Molecular Assessment of Histopathological Staging in Squamous-Cell Carcinoma of the Head and Neck

    Joseph A. Brennan;Li Mao;Ralph H. Hruban;Jay O. Boyle

  • Phosphodiesterase-5 inhibition augments endogenous antitumor immunity by reducing myeloid-derived suppressor cell function

    Paolo Serafini;Kristen Meckel;Michael Kelso;Kimberly Noonan

  • TP53 mutations and survival in squamous-cell carcinoma of the head and neck.

    M. Luana Poeta;M. Luana Poeta;Judith Manola;Meredith A. Goldwasser;Arlene Forastiere

  • Association between Cigarette Smoking and Mutation of the p53 Gene in Squamous-Cell Carcinoma of the Head and Neck

    Joseph A. Brennan;Jay O. Boyle;Wayne M. Koch;Steven N. Goodman

  • High Frequency of p16 (CDKN2/MTS-1/INK4A) Inactivation in Head and Neck Squamous Cell Carcinoma

    Andre L. Reed;Joseph Califano;Paul Cairns;William H. Westra

  • Frequency of homozygous deletion at p16/CDKN2 in primary human tumours

    P. Cairns;T. J. Polascik;Y. Eby;K. Tokino

  • The Incidence of p53 Mutations Increases with Progression of Head and Neck Cancer

    Jay O. Boyle;John Hakim;Wayne Koch;Peter van der Riet

  • Gene Promoter Hypermethylation in Tumors and Serum of Head and Neck Cancer Patients

    Montserrat Sanchez-Cespedes;Manel Esteller;Li Wu;Homaira Nawroz-Danish

  • Detection of somatic mutations and HPV in the saliva and plasma of patients with head and neck squamous cell carcinomas.

    Yuxuan Wang;Simeon Springer;Carolyn L. Mulvey;Natalie Silliman

  • Promoter Hypermethylation Patterns of p16, O6-Methylguanine-DNA-methyltransferase, and Death-associated Protein Kinase in Tumors and Saliva of Head and Neck Cancer Patients

    Siane Lopes Bittencourt Rosas;Siane Lopes Bittencourt Rosas;Wayne Koch;Maria da Gloria da Costa Carvalho;Li Wu

  • CYSTIC LYMPH NODE METASTASIS IN PATIENTS WITH HEAD AND NECK CANCER: AN HPV-ASSOCIATED PHENOMENON

    David Goldenberg;Shahnaz Begum;William H. Westra;Zubair Khan

  • Allelotype of Head and Neck Squamous Cell Carcinoma

    Nawroz H;van der Riet P;Hruban Rh;Koch W

  • Frequent loss of chromosome 9p21-22 early in head and neck cancer progression.

    P. Van Der Riet;H. Nawroz;R. H. Hruban;R. Corio

  • A genetic progression model for head and neck cancer: Implications for field cancerization

    Joseph A. Califano;Gary Clayman;David Sidransky;Wayne Koch

Frequent Co-Authors

Joseph A. Califano
Joseph A. Califano University of California, San Diego
David Sidransky
David Sidransky Johns Hopkins University School of Medicine
William H. Westra
William H. Westra Icahn School of Medicine at Mount Sinai
David W. Eisele
David W. Eisele Johns Hopkins University
David M. Goldenberg
David M. Goldenberg Immunomedics (United States)
Arlene A. Forastiere
Arlene A. Forastiere Johns Hopkins University
Marianna Zahurak
Marianna Zahurak Johns Hopkins University
Robert L. Ferris
Robert L. Ferris University of Pittsburgh
Carmen Jerónimo
Carmen Jerónimo University of Porto
Jin Jen
Jin Jen Bristol Myers Squibb

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