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Medicine

D-Index
108
Citations
54204
World Ranking
5917
National Ranking
3170

Research.com Recognitions

  • 2012 - Member of the National Academy of Medicine (NAM)
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians

Overview

Jennifer R. Grandis is affiliated with the University of California, San Francisco in the United States. Their research spans a broad range of medicine and molecular biology topics, with notable focus on oncology, pulmonary and respiratory medicine, and otorhinolaryngology. Their scholarly contributions cover both clinical and molecular aspects of cancer research.

Their recent published work includes:

  • "Head and neck squamous cell carcinoma" (2020) in Nature Reviews Disease Primers
  • "Discovering dominant tumor immune archetypes in a pan-cancer census" (2021) in Cell
  • "Targeting the JAK/STAT pathway in solid tumors" (2020) in Journal of Cancer Metastasis and Treatment
  • "The contemporary management of cancers of the sinonasal tract in adults" (2022) in CA A Cancer Journal for Clinicians
  • "Disruption of the HER3-PI3K-mTOR oncogenic signaling axis and PD-1 blockade as a multimodal precision immunotherapy in head and neck cancer" (2021) in Nature Communications

Frequent co-authors in their research include:

  • Daniel E. Johnson
  • Umamaheswar Duvvuri
  • Yan Zeng
  • Julie E. Bauman
  • Neil E. Bhola

Publications by Jennifer R. Grandis have appeared multiple times in several venues specializing in cancer and clinical research, such as:

  • Cancer Research
  • Clinical Cancer Research
  • Cancers
  • CA A Cancer Journal for Clinicians
  • Molecular Cancer Therapeutics

Their main fields of study encompass Medicine and Biochemistry, Genetics and Molecular Biology. Within these, subfields of particular focus include Molecular Biology, Oncology, Pulmonary and Respiratory Medicine, Otorhinolaryngology, and Public Health, Environmental and Occupational Health.

The primary research topics addressed involve:

  • Head and Neck Cancer Studies
  • Lung Cancer Treatments and Mutations
  • Cancer-related gene regulation
  • Cancer-related Molecular Pathways
  • PI3K/AKT/mTOR signaling in cancer
  • Cancer Immunotherapy and Biomarkers
  • Diversity and Career in Medicine

Jennifer R. Grandis has been recognized with membership in significant professional organizations, including:

  • Member of the National Academy of Medicine (NAM), 2012
  • Member of the Association of American Physicians

Best Publications

  • Comprehensive genomic characterization of head and neck squamous cell carcinomas

    Michael S. Lawrence;Carrie Sougnez;Lee Lichtenstein;Kristian Cibulskis

  • The Mutational Landscape of Head and Neck Squamous Cell Carcinoma

    N. Stransky;A. M. Egloff;A. D. Tward;A. D. Kostic

  • Head and neck squamous cell carcinoma

    Daniel E. Johnson;Barbara Burtness;C. René Leemans;Vivian Wai Yan Lui

  • Targeting the IL-6/JAK/STAT3 signalling axis in cancer.

    Daniel E. Johnson;Rachel A. O'Keefe;Jennifer R. Grandis

  • WHO classification of head and neck tumours

    Adel K El-Naggar;John K. C Chan;Jennifer Rubin Grandis;隆 高田

  • Levels of TGF-α and EGFR Protein in Head and Neck Squamous Cell Carcinoma and Patient Survival

    Jennifer Rubin Grandis;Mona F. Melhem;William E. Gooding;Roger Day

  • Elevated Levels of Transforming Growth Factor α and Epidermal Growth Factor Receptor Messenger RNA Are Early Markers of Carcinogenesis in Head and Neck Cancer

    Jennifer Rubin Grandis;David J. Tweardy

  • Epidermal Growth Factor Receptor Biology in Head and Neck Cancer

    Shailaja Kalyankrishna;Jennifer R. Grandis

  • Constitutive activation of Stat3 signaling abrogates apoptosis in squamous cell carcinogenesis in vivo.

    Jennifer Rubin Grandis;Stephanie D. Drenning;Qing Zeng;Simon C. Watkins

  • Requirement of Stat3 but not Stat1 activation for epidermal growth factor receptor- mediated cell growth In vitro.

    Jennifer Rubin Grandis;Stephanie D. Drenning;Arup Chakraborty;Min Yu Zhou

  • Mutant Epidermal Growth Factor Receptor (EGFRvIII) Contributes to Head and Neck Cancer Growth and Resistance to EGFR Targeting

    John C. Sok;Francesca M. Coppelli;Sufi M. Thomas;Miriam N. Lango

  • Frequent mutation of the PI3K pathway in head and neck cancer defines predictive biomarkers

    Vivian W.Y. Lui;Matthew L. Hedberg;Hua Li;Bhavana S. Vangara

  • STAT signaling in head and neck cancer.

    John I Song;Jennifer Rubin Grandis

  • Targeted inhibition of Stat3 with a decoy oligonucleotide abrogates head and neck cancer cell growth.

    Paul L. Leong;Genevieve A. Andrews;Daniel E. Johnson;Kevin F. Dyer

  • STAT3 signaling: anticancer strategies and challenges.

    Paul A. Johnston;Jennifer R. Grandis

  • Characterization of HPV and host genome interactions in primary head and neck cancers.

    Michael Parfenov;Chandra Sekhar Pedamallu;Nils Gehlenborg;Nils Gehlenborg;Samuel S. Freeman

  • The changing face of malignant (necrotising) external otitis: clinical, radiological, and anatomic correlations.

    Jennifer Rubin Grandis;Barton F Branstetter;Victor L Yu

  • Signaling through the epidermal growth factor receptor during the development of malignancy

    Jennifer Rubin Grandis;John C. Sok

  • Combined Targeting of the Estrogen Receptor and the Epidermal Growth Factor Receptor in Non–Small Cell Lung Cancer Shows Enhanced Antiproliferative Effects

    Laura P. Stabile;Jennifer S. Lyker;Christopher T. Gubish;Weiping Zhang

  • STAT‐mediated EGFR signaling in cancer

    Kelly M. Quesnelle;Amanda L. Boehm;Jennifer R. Grandis

Frequent Co-Authors

William E. Gooding
William E. Gooding University of Pittsburgh
Daniel E. Johnson
Daniel E. Johnson University of California, San Francisco
Robert L. Ferris
Robert L. Ferris University of Pittsburgh
Jonas T. Johnson
Jonas T. Johnson University of Pittsburgh
Jill M. Siegfried
Jill M. Siegfried University of Minnesota
Raja R. Seethala
Raja R. Seethala University of Pittsburgh
Gordon B. Mills
Gordon B. Mills Oregon Health & Science University
Levi A. Garraway
Levi A. Garraway Roche (United States)
Joel L. Weissfeld
Joel L. Weissfeld University of Pittsburgh
Qing Zhang
Qing Zhang Nanyang Technological University

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