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Biology and Biochemistry

D-Index
72
Citations
15623
World Ranking
6421
National Ranking
2996

Overview

Jill M. Siegfried is affiliated with the University of Minnesota in the United States and has focused their research primarily within the field of Medicine. Their work spans 27 publications, with particular emphasis on Oncology, Pulmonary and Respiratory Medicine, and Immunology among other subfields.

The scientist's research interests cover a wide range of topics including:

  • Global Cancer Incidence and Screening
  • Chronic Obstructive Pulmonary Disease (COPD) Research
  • Cancer Immunotherapy and Biomarkers
  • Asthma and respiratory diseases
  • CAR-T cell therapy research
  • Monoclonal and Polyclonal Antibodies Research
  • Nanowire Synthesis and Applications

Siegfried has published in several academic venues, frequently contributing to:

  • Cancer Prevention Research
  • Australian Economic Papers
  • Endocrinology
  • Journal of Medicinal Chemistry
  • Cancer

Recent significant papers include:

  • "Sex and Gender Differences in Lung Cancer and Chronic Obstructive Lung Disease," 2021, Endocrinology
  • "Anti-EGFR Fibronectin Bispecific Chemically Self-Assembling Nanorings (CSANs) Induce Potent T Cell-Mediated Antitumor Responses and Downregulation of EGFR Signaling and PD-1/PD-L1 Expression," 2020, Journal of Medicinal Chemistry
  • "Targeting the ERβ/HER Oncogenic Network in KRAS Mutant Lung Cancer Modulates the Tumor Microenvironment and Is Synergistic with Sequential Immunotherapy," 2021, International Journal of Molecular Sciences
  • "The American Cancer Society National Lung Cancer Roundtable strategic plan: Lung cancer in women," 2024, Cancer
  • "Early natural menopause is associated with poor lung health and increased mortality among female smokers," 2022, American Journal of Obstetrics and Gynecology

Siegfried has collaborated frequently with several researchers, including:

  • Abdulaziz A. Almotlak
  • Mariya Farooqui
  • Laura P. Stabile
  • Ozgun Kilic
  • Marcos Romário Matos de Souza

Best Publications

  • Comprehensive molecular profiling of lung adenocarcinoma: The cancer genome atlas research network

    Eric A. Collisson;Joshua D. Campbell;Angela N. Brooks;Angela N. Brooks;Alice H. Berger

  • Comprehensive genomic characterization of squamous cell lung cancers

    Peter S. Hammerman;Doug Voet;Michael S. Lawrence;Douglas Voet

  • Human non-small cell lung tumors and cells derived from normal lung express both estrogen receptor α and β and show biological responses to estrogen

    Laura P. Stabile;Autumn L. Gaither Davis;Christopher T. Gubish;Toni M. Hopkins

  • Association of Radiographic Emphysema and Airflow Obstruction with Lung Cancer

    David O. Wilson;Joel L. Weissfeld;Arzu Balkan;Arzu Balkan;Jeffrey G. Schragin

  • Combined Targeting of the Estrogen Receptor and the Epidermal Growth Factor Receptor in Non–Small Cell Lung Cancer Shows Enhanced Antiproliferative Effects

    Laura P. Stabile;Jennifer S. Lyker;Christopher T. Gubish;Weiping Zhang

  • Progress in chemoprevention drug development: the promise of molecular biomarkers for prevention of intraepithelial neoplasia and cancer--a plan to move forward.

    Gary J. Kelloff;Scott M. Lippman;Andrew J. Dannenberg;Caroline C. Sigman

  • The Pittsburgh Lung Screening Study (PLuSS): outcomes within 3 years of a first computed tomography scan.

    David O. Wilson;Joel L. Weissfeld;Carl R. Fuhrman;Stephen N. Fisher

  • Unlocking Biomarker Discovery: Large Scale Application of Aptamer Proteomic Technology for Early Detection of Lung Cancer

    Rachel M. Ostroff;William L. Bigbee;Wilbur Franklin;Larry Gold

  • HGF and c-Met Participate in Paracrine Tumorigenic Pathways in Head and Neck Squamous Cell Cancer

    Lynn M. Knowles;Laura P. Stabile;Ann Marie Egloff;Mary E. Rothstein

  • Sex-Specific Expression of Gastrin-Releasing Peptide Receptor: Relationship to Smoking History and Risk of Lung Cancer

    Sharon Persinger Shriver;Heather A. Bourdeau;Christopher T. Gubish;Dayna L. Tirpak

  • Genetic instability of microsatellite sequences in many non-small cell lung carcinomas.

    Viji Shridhar;Jill Siegfried;Jay Hunt;Maria del Mar Alonso

  • Association of immunoreactive hepatocyte growth factor with poor survival in resectable non-small cell lung cancer.

    Jill M. Siegfried;Lisa A. Weissfeld;Praveena Singh-Kaw;Robert J. Weyant

  • Detection of K-ras mutations in lung carcinomas: relationship to prognosis.

    Phouthone Keohavong;Mary Ann A DeMichele;Alea C. Melacrinos;Rodney J. Landreneau

  • Comparative Genomic Hybridization Analysis Detects Frequent, Often High-Level, Overrepresentation of DNA Sequences at 3q, 5p, 7p, and 8q in Human Non-Small Cell Lung Carcinomas

    Binaifer R. Balsara;Gonosuke Sonoda;Stanislas Du Manoir;Jill M. Siegfried

  • Downregulation of Dkk3 activates β-catenin/TCF-4 signaling in lung cancer

    Wen Yue;Quanhong Sun;Sanja Dacic;Rodney J. Landreneau

  • Regulation of endogenous gene expression in human non-small cell lung cancer cells by estrogen receptor ligands.

    Pamela A. Hershberger;A. Cecilia Vasquez;Beatriz Kanterewicz;Stephanie Land

  • Recurrent Deletions of Specific Chromosomal Sites in 1p, 3p, 6q, and 9p in Human Malignant Mesothelioma

    Takahiro Taguchi;Suresh C. Jhanwar;Jill M. Siegfried;Steven M. Keller

  • Women and lung cancer: does oestrogen play a role?

    Jill M Siegfried

  • SRC family kinases mediate epidermal growth factor receptor ligand cleavage, proliferation, and invasion of head and neck cancer cells.

    Qing Zhang;Sufi M. Thomas;Sichuan Xi;Thomas E. Smithgall

  • Phosphorylation of TNF-α converting enzyme by gastrin-releasing peptide induces amphiregulin release and EGF receptor activation

    Qing Zhang;Sufi M. Thomas;Vivian Wai Yan Lui;Sichuan Xi

Frequent Co-Authors

Jennifer R. Grandis
Jennifer R. Grandis University of California, San Francisco
James D. Luketich
James D. Luketich University of Pittsburgh
Joel L. Weissfeld
Joel L. Weissfeld University of Pittsburgh
Rodney J. Landreneau
Rodney J. Landreneau University of Pittsburgh
Joseph R. Testa
Joseph R. Testa Fox Chase Cancer Center
William E. Gooding
William E. Gooding University of Pittsburgh
Steven A. Belinsky
Steven A. Belinsky University of New Mexico
Mark A. Socinski
Mark A. Socinski University of North Carolina at Chapel Hill
Naftali Kaminski
Naftali Kaminski Yale University
Thomas P. Conrads
Thomas P. Conrads University of Pittsburgh

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