D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Genetics and Molecular Biology D-index 69 Citations 16,570 187 World Ranking 1578 National Ranking 809

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Cancer
  • DNA

His main research concerns DNA methylation, Epigenetics, Cancer research, Methylation and CpG site. The DNA methylation study combines topics in areas such as Carcinogenesis and Molecular biology. His Epigenetics research includes elements of Cancer, Ovarian cancer, Tissue microarray, DNA demethylation and Gene silencing.

His study in Cancer research is interdisciplinary in nature, drawing from both Beta-catenin, Wnt signaling pathway, Estrogen receptor, Estrogen receptor alpha and Tumor suppressor gene. His studies in Methylation integrate themes in fields like Microarray, Pathology and Adenocarcinoma. His CpG site study combines topics in areas such as Chromatin and CpG Island Methylator Phenotype.

His most cited work include:

  • Identification and characterization of ovarian cancer-initiating cells from primary human tumors. (994 citations)
  • Gene silencing in cancer by histone H3 lysine 27 trimethylation independent of promoter DNA methylation (534 citations)
  • Methylation Profiling of CpG Islands in Human Breast Cancer Cells (456 citations)

What are the main themes of his work throughout his whole career to date?

Tim H M Huang mainly investigates DNA methylation, Cancer research, Epigenetics, Genetics and Methylation. The various areas that Tim H M Huang examines in his DNA methylation study include Carcinogenesis, Cancer and Molecular biology. His work carried out in the field of Cancer research brings together such families of science as Estrogen receptor alpha, Gene silencing, Tumor suppressor gene, Breast cancer and Prostate cancer.

In his study, Endocrinology is strongly linked to Internal medicine, which falls under the umbrella field of Epigenetics. As part of the same scientific family, Tim H M Huang usually focuses on Genetics, concentrating on Computational biology and intersecting with Gene expression profiling. His Methylation research is multidisciplinary, incorporating elements of Microarray and Bioinformatics.

He most often published in these fields:

  • DNA methylation (50.42%)
  • Cancer research (41.27%)
  • Epigenetics (31.86%)

What were the highlights of his more recent work (between 2015-2021)?

  • Cancer research (41.27%)
  • DNA methylation (50.42%)
  • Cell biology (8.03%)

In recent papers he was focusing on the following fields of study:

Tim H M Huang mostly deals with Cancer research, DNA methylation, Cell biology, Prostate cancer and Epigenetics. His Cancer research research includes themes of Carcinogenesis, Cancer, Metastasis, Endometrial cancer and Transcriptome. He combines subjects such as Receptor tyrosine kinase, Molecular biology, Downregulation and upregulation and Transcription factor with his study of Cancer.

His research integrates issues of Biomarker, Internal medicine, Regulation of gene expression and Methylation in his study of DNA methylation. Tim H M Huang interconnects Tumor suppressor gene and Reprimo in the investigation of issues within Methylation. His Epigenetics study frequently involves adjacent topics like DNA.

Between 2015 and 2021, his most popular works were:

  • NF-κB-HOTAIR Axis Links DNA Damage Response, Chemoresistance and Cellular Senescence in Ovarian Cancer (144 citations)
  • Cross-talk among writers, readers, and erasers of m6A regulates cancer growth and progression (87 citations)
  • Diverse AR-V7 cistromes in castration-resistant prostate cancer are governed by HoxB13. (52 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Cancer
  • DNA

Cancer research, DNA methylation, Methylation, Regulation of gene expression and Carcinogenesis are his primary areas of study. The Cancer research study combines topics in areas such as Transcription factor, EZH2, Cell cycle and Prostate cancer, Androgen receptor. His DNA methylation research incorporates themes from Internal medicine, Epigenetics and Endometrial cancer.

Tim H M Huang has researched Methylation in several fields, including Biomarker, Cancer, Bisulfite sequencing and Cell cycle checkpoint. His Regulation of gene expression study focuses on Gene and Genetics. His studies in Carcinogenesis integrate themes in fields like Enhancer and Estrogen receptor.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Identification and characterization of ovarian cancer-initiating cells from primary human tumors.

Shu Zhang;Curt Balch;Michael W. Chan;Hung Cheng Lai.
Cancer Research (2008)

1433 Citations

Methylation Profiling of CpG Islands in Human Breast Cancer Cells

Tim Hui Ming Huang;Martin R. Perry;Douglas E. Laux.
Human Molecular Genetics (1999)

700 Citations

Gene silencing in cancer by histone H3 lysine 27 trimethylation independent of promoter DNA methylation

Yutaka Kondo;Lanlan Shen;Alfred S. Cheng;Alfred S. Cheng;Saira Ahmed.
Nature Genetics (2008)

673 Citations

Isolating human transcription factor targets by coupling chromatin immunoprecipitation and CpG island microarray analysis

Amy S. Weinmann;Pearlly S. Yan;Matthew J. Oberley;Tim Hui Ming Huang.
Genes & Development (2002)

583 Citations

FOXP3 is an X-linked breast cancer suppressor gene and an important repressor of the HER-2/ErbB2 oncogene

Tao Zuo;Lizhong Wang;Carl Morrison;Xing Chang.
Cell (2007)

437 Citations

Methyl-CpG binding proteins identify novel sites of epigenetic inactivation in human cancer

Esteban Ballestar;Maria F. Paz;Laura Valle;Susan Wei.
The EMBO Journal (2003)

404 Citations

Methylation-Specific Oligonucleotide Microarray: A New Potential for High-Throughput Methylation Analysis

Raad S. Gitan;Huidong Shi;Chuan Mu Chen;Pearlly S. Yan.
Genome Research (2002)

388 Citations

The functional consequences of alternative promoter use in mammalian genomes

Ramana V. Davuluri;Ramana V. Davuluri;Yutaka Suzuki;Sumio Sugano;Christoph Plass;Christoph Plass.
Trends in Genetics (2008)

359 Citations

Dissecting Complex Epigenetic Alterations in Breast Cancer Using CpG Island Microarrays

Pearlly S. Yan;Chuan-Mu Chen;Huidong Shi;Farahnaz Rahmatpanah.
Cancer Research (2001)

324 Citations

Epigenetic Repression of microRNA-129-2 Leads to Overexpression of SOX4 Oncogene in Endometrial Cancer

Yi Wen Huang;Joseph C. Liu;Daniel E. Deatherage;Jingqin Luo.
Cancer Research (2009)

323 Citations

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