His scientific interests lie mostly in DNA methylation, Epigenetics, Genetics, Molecular biology and Histone. His work deals with themes such as Autoimmune disease, Myeloid Cell Differentiation and DNA, which intersect with DNA methylation. His Epigenetics research is multidisciplinary, incorporating perspectives in Epigenesis, Cancer research and CpG site.
In general Genetics study, his work on Epigenetics of physical exercise, Histone methylation and Genotype often relates to the realm of Lupus erythematosus, thereby connecting several areas of interest. His work carried out in the field of Molecular biology brings together such families of science as Lesion, Apolipoprotein E, Histone methyltransferase and Trichostatin A. Many of his research projects under Histone are closely connected to Nucleic acid amplification technique with Nucleic acid amplification technique, tying the diverse disciplines of science together.
Esteban Ballestar mainly investigates DNA methylation, Epigenetics, Genetics, Molecular biology and Cancer research. His study focuses on the intersection of DNA methylation and fields such as Methylation with connections in the field of Promoter. Esteban Ballestar has researched Epigenetics in several fields, including Cancer, Immunology, Histone, Disease and Regulation of gene expression.
His Molecular biology research also works with subjects such as
Esteban Ballestar spends much of his time researching DNA methylation, Epigenetics, Cancer research, Immunology and Regulation of gene expression. His work in the fields of DNA methylation, such as DNA demethylation, intersects with other areas such as Activation-induced deaminase. Epigenetics is a subfield of Genetics that he studies.
His work on Histone and Genetic architecture as part of general Genetics research is often related to Extracellular matrix organization, thus linking different fields of science. Esteban Ballestar interconnects Mesenchymal stem cell, Bone marrow and Multiple myeloma in the investigation of issues within Cancer research. His research investigates the connection with Regulation of gene expression and areas like Cellular differentiation which intersect with concerns in Cell biology, C2C12, Myogenesis and Skeletal muscle cell differentiation.
Esteban Ballestar mostly deals with DNA methylation, Cell biology, Epigenetics, Immunology and Regulation of gene expression. As a member of one scientific family, Esteban Ballestar mostly works in the field of DNA methylation, focusing on Cancer research and, on occasion, Tumor progression, Microvesicles, Cancer cell, Carcinogenesis and Tumor microenvironment. The various areas that Esteban Ballestar examines in his Cell biology study include Autophagy, Cellular differentiation, Conditional gene knockout, Histone code and Histone deacetylase.
In his research on the topic of Epigenetics, Epigenesis, Epigenetic biomarkers, Personalized medicine, Epigenomics and Bioinformatics is strongly related with Cancer. His Immunology research includes elements of Familial Mediterranean fever and Methylation. Esteban Ballestar has included themes like Skeletal muscle cell differentiation, Inflammasome, AIM2, Tet methylcytosine dioxygenase 2 and Autoinflammatory Syndrome in his Regulation of gene expression study.
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Epigenetic differences arise during the lifetime of monozygotic twins
Mario F. Fraga;Esteban Ballestar;Maria F. Paz;Santiago Ropero.
Proceedings of the National Academy of Sciences of the United States of America (2005)
Loss of acetylation at Lys16 and trimethylation at Lys20 of histone H4 is a common hallmark of human cancer
Mario F Fraga;Esteban Ballestar;Ana Villar-Garea;Manuel Boix-Chornet.
Nature Genetics (2005)
Genetic Unmasking of an Epigenetically Silenced microRNA in Human Cancer Cells
Amaia Lujambio;Santiago Ropero;Esteban Ballestar;Mario F. Fraga.
Cancer Research (2007)
Mi-2 complex couples DNA methylation to chromatin remodelling and histone deacetylation.
Paul A. Wade;Anne Gegonne;Peter L. Jones;Esteban Ballestar.
Nature Genetics (1999)
Autophagy maintains stemness by preventing senescence
García-Prat L;Martínez-Vicente M;Perdiguero E;Ortet L.
Snail mediates E-cadherin repression by the recruitment of the Sin3A/histone deacetylase 1 (HDAC1)/HDAC2 complex.
Hector Peinado;Esteban Ballestar;Manel Esteller;Amparo Cano.
Molecular and Cellular Biology (2004)
Geriatric muscle stem cells switch reversible quiescence into senescence
Pedro Sousa-Victor;Pedro Sousa-Victor;Susana Gutarra;Laura García-Prat;Javier Rodriguez-Ubreva.
Changes in the pattern of DNA methylation associate with twin discordance in systemic lupus erythematosus
Biola M. Javierre;Agustin F. Fernandez;Julia Richter;Fatima Al-Shahrour.
Genome Research (2010)
Notch Signaling Is Essential for Ventricular Chamber Development
Joaquín Grego-Bessa;Luis Luna-Zurita;Gonzalo del Monte;Victoria Bolós.
Developmental Cell (2007)
Methyl-CpG-binding proteins. Targeting specific gene repression.
Esteban Ballestar;Alan P. Wolffe.
FEBS Journal (2001)
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