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Immunology

D-Index
70
Citations
13523
World Ranking
2453
National Ranking
1173

Overview

Amr H. Sawalha is affiliated with the University of Pittsburgh in the United States and has contributed extensively to the field of medicine, focusing on areas such as rheumatology and immunology. Their research spans across multiple subfields, including molecular biology, infectious diseases, and pathology and forensic medicine.

The scientist's main research topics include systemic lupus erythematosus, rheumatoid arthritis, T-cell and B-cell immunology, immune cell function and interaction, COVID-19 clinical research studies, autoimmune and inflammatory disorders, and systemic sclerosis and related diseases.

Some of Amr H. Sawalha's recent publications are:

  • "COVID-19 and autoimmune diseases," 2020, published in Current Opinion in Rheumatology
  • "COVID-19: A review of therapeutic strategies and vaccine candidates," 2020, Clinical Immunology
  • "Epigenetic dysregulation of ACE2 and interferon-regulated genes might suggest increased COVID-19 susceptibility and severity in lupus patients," 2020, Clinical Immunology
  • "A disease-associated gene desert directs macrophage inflammation through ETS2," 2024, Nature
  • "Clinical value of DNA methylation markers in autoimmune rheumatic diseases," 2020, Nature Reviews Rheumatology

Amr H. Sawalha frequently collaborates with several co-authors, including:

  • Kelli D. Allen
  • Joshua F. Baker
  • Bonnie L. Bermas
  • Patrick Coit
  • Susan A. Boackle

They have published papers predominantly in the following journals and venues:

  • Arthritis & Rheumatology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Arthritis Care & Research
  • Clinical Immunology
  • ACR Open Rheumatology

In total, their work covers 164 publications in the broad medical field, with a significant focus on rheumatology (56 publications) and immunology (52 publications).

Best Publications

  • Changes in the pattern of DNA methylation associate with twin discordance in systemic lupus erythematosus

    Biola M. Javierre;Agustin F. Fernandez;Julia Richter;Fatima Al-Shahrour

  • COVID-19 and autoimmune diseases.

    Yu Liu;Amr H. Sawalha;Qianjin Lu;Qianjin Lu

  • Genome-wide DNA methylation study suggests epigenetic accessibility and transcriptional poising of interferon-regulated genes in naïve CD4+ T cells from lupus patients

    Patrick Coit;Matlock Jeffries;Nezam Altorok;Mikhail G. Dozmorov

  • COVID-19: A review of therapeutic strategies and vaccine candidates.

    Vladislav Izda;Matlock A. Jeffries;Matlock A. Jeffries;Amr H. Sawalha

  • Epigenetic dysregulation of ACE2 and interferon-regulated genes might suggest increased COVID-19 susceptibility and severity in lupus patients.

    Amr H. Sawalha;Ming Zhao;Patrick Coit;Qianjin Lu

  • Genetic association of interleukin-21 polymorphisms with systemic lupus erythematosus.

    Amr H Sawalha;Amr H Sawalha;Amr H Sawalha;Kenneth M Kaufman;Kenneth M Kaufman;Kenneth M Kaufman;Jennifer A Kelly;Adam J Adler

  • Genome-wide DNA methylation patterns in CD4+ T cells from patients with systemic lupus erythematosus

    Matlock A. Jeffries;Mikhail Dozmorov;Yuhong Tang;Joan T. Merrill

  • Impaired DNA methylation and its mechanisms in CD4(+)T cells of systemic lupus erythematosus.

    Yiqun Zhang;Ming Zhao;Amr H. Sawalha;Bruce Richardson

  • IFI44L promoter methylation as a blood biomarker for systemic lupus erythematosus

    Ming Zhao;Yin Zhou;Bochen Zhu;Mengjie Wan

  • Early disease onset is predicted by a higher genetic risk for lupus and is associated with a more severe phenotype in lupus patients

    Ryan Webb;Jennifer A Kelly;Emily C Somers;Travis Hughes

  • Identification of Multiple Genetic Susceptibility Loci in Takayasu Arteritis

    Güher Saruhan-Direskeneli;Travis Hughes;Kenan Aksu;Gokhan Keser

  • DNA methylation and mRNA and microRNA expression of SLE CD4+ T cells correlate with disease phenotype

    Ming Zhao;Siyang Liu;Shuangyan Luo;Honglong Wu

  • Genome-wide DNA methylation patterns in naive CD4+ T cells from patients with primary Sjögren's syndrome.

    Nezam Altorok;Patrick Coit;Travis Hughes;Kristi A. Koelsch

  • Impaired T Cell Protein Kinase Cδ Activation Decreases ERK Pathway Signaling in Idiopathic and Hydralazine-Induced Lupus

    Gabriela Gorelik;Jing Yuan Fang;Ailing Wu;Amr H. Sawalha

  • Epigenome profiling reveals significant DNA demethylation of interferon signature genes in lupus neutrophils

    Patrick Coit;Srilakshmi Yalavarthi;Mikhail Ognenovski;Wenpu Zhao

  • Drug-induced lupus erythematosus: an update on drugs and mechanisms.

    Ye He;Ye He;Amr H. Sawalha

  • Identification of multiple independent susceptibility loci in the HLA region in Behçet's disease

    Travis Hughes;Patrick Coit;Adam Adler;Vuslat Yilmaz

  • Renal involvement in lupus is characterized by unique DNA methylation changes in naïve CD4+ T cells.

    Patrick Coit;Paul Renauer;Matlock A. Jeffries;Joan T. Merrill

  • Autoimmunity and Klinefelter's syndrome: When men have two X chromosomes

    Amr H. Sawalha;John B. Harley;John B. Harley;John B. Harley;R. Hal Scofield;R. Hal Scofield;R. Hal Scofield

  • Genome-wide DNA methylation analysis in dermal fibroblasts from patients with diffuse and limited systemic sclerosis reveals common and subset-specific DNA methylation aberrancies

    Nezam Altorok;Pei Suen Tsou;Patrick Coit;Dinesh Khanna

  • Genome-wide DNA methylation study identifies significant epigenomic changes in osteoarthritic cartilage.

    Matlock A. Jeffries;Madison Donica;Lyle W. Baker;Michael E. Stevenson

  • Identification of novel genetic susceptibility loci for Behçet's disease using a genome-wide association study

    Yiping Fei;Yiping Fei;Ryan Webb;Ryan Webb;Beth L Cobb;Haner Direskeneli

  • Common Variants within MECP2 Confer Risk of Systemic Lupus Erythematosus

    Amr H. Sawalha;Amr H. Sawalha;Amr H. Sawalha;Ryan Webb;Shizhong Han;Jennifer A. Kelly

Frequent Co-Authors

John B. Harley
John B. Harley United States Department of Veterans Affairs
Judith A. James
Judith A. James Oklahoma Medical Research Foundation
Marta E. Alarcón-Riquelme
Marta E. Alarcón-Riquelme University of Granada
Kenneth M. Kaufman
Kenneth M. Kaufman Cincinnati Children's Hospital Medical Center
R. Hal Scofield
R. Hal Scofield University of Oklahoma Health Sciences Center
Jonathan D. Wren
Jonathan D. Wren Oklahoma Medical Research Foundation
Jennifer A. Kelly
Jennifer A. Kelly Oklahoma Medical Research Foundation
Timothy J. Vyse
Timothy J. Vyse King's College London
Gary S. Gilkeson
Gary S. Gilkeson Medical University of South Carolina
Robert P. Kimberly
Robert P. Kimberly University of Alabama at Birmingham

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