His scientific interests lie mostly in Immunology, DNA methylation, Systemic lupus erythematosus, Epigenetics and Genetics. Amr H. Sawalha has researched Immunology in several fields, including Single-nucleotide polymorphism and Genetic predisposition. His Single-nucleotide polymorphism course of study focuses on Haplotype and Candidate gene.
His DNA methylation research integrates issues from Molecular biology and Methylation. He combines subjects such as T cell and Interferon with his study of Systemic lupus erythematosus. Epigenetics is a primary field of his research addressed under Gene.
His primary scientific interests are in Immunology, Systemic lupus erythematosus, Genetics, DNA methylation and Epigenetics. His Immunology research incorporates themes from Single-nucleotide polymorphism and Disease, Genetic predisposition. His Systemic lupus erythematosus research incorporates elements of Interferon, Autoimmunity, Malar rash and Rheumatology.
His work carried out in the field of DNA methylation brings together such families of science as Molecular biology, Cancer research and Methylation. His Epigenetics study combines topics in areas such as Epigenomics, Histone, microRNA and Pathogenesis. His studies deal with areas such as Genotyping and Candidate gene as well as Genetic association.
Amr H. Sawalha spends much of his time researching Systemic lupus erythematosus, Cancer research, Epigenetics, Immunology and DNA methylation. His Systemic lupus erythematosus research includes elements of Hydroxychloroquine, Coronavirus disease 2019, Proinflammatory cytokine, Lupus nephritis and Autoimmunity. His Cancer research research is multidisciplinary, incorporating perspectives in Chromatin, EZH2, Cell type and GPNMB.
The study incorporates disciplines such as Interferon and Methylation in addition to DNA methylation. The Methylation study combines topics in areas such as Ankylosing spondylitis, Single-nucleotide polymorphism and HLA-B. Gene is a subfield of Genetics that Amr H. Sawalha tackles.
Immunology, Epigenetics, DNA methylation, Cancer research and Systemic lupus erythematosus are his primary areas of study. The Immune system research Amr H. Sawalha does as part of his general Immunology study is frequently linked to other disciplines of science, such as Viral entry, therefore creating a link between diverse domains of science. As part of one scientific family, Amr H. Sawalha deals mainly with the area of Epigenetics, narrowing it down to issues related to the Allele, and often CpG site, Single-nucleotide polymorphism, Ankylosing spondylitis and Methylation.
As part of his inquiry into Gene and Genetics, he is doing DNA methylation research. His Cancer research study incorporates themes from Chromatin, GPNMB, Locus and Chromosome conformation capture. His biological study spans a wide range of topics, including Tumor necrosis factor alpha, Hydroxychloroquine, Cytokine storm, Coronavirus disease 2019 and Viremia.
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Changes in the pattern of DNA methylation associate with twin discordance in systemic lupus erythematosus
Biola M. Javierre;Agustin F. Fernandez;Julia Richter;Fatima Al-Shahrour.
Genome Research (2010)
Genome-wide DNA methylation study suggests epigenetic accessibility and transcriptional poising of interferon-regulated genes in naïve CD4+ T cells from lupus patients
Patrick Coit;Matlock Jeffries;Nezam Altorok;Mikhail G. Dozmorov.
Journal of Autoimmunity (2013)
Genetic association of interleukin-21 polymorphisms with systemic lupus erythematosus.
Amr H Sawalha;Amr H Sawalha;Amr H Sawalha;Kenneth M Kaufman;Kenneth M Kaufman;Kenneth M Kaufman;Jennifer A Kelly;Adam J Adler.
Annals of the Rheumatic Diseases (2007)
Genome-wide DNA methylation patterns in CD4+ T cells from patients with systemic lupus erythematosus
Matlock A. Jeffries;Mikhail Dozmorov;Yuhong Tang;Joan T. Merrill.
COVID-19 and autoimmune diseases.
Yu Liu;Amr H. Sawalha;Qianjin Lu;Qianjin Lu.
Current Opinion in Rheumatology (2021)
Epigenetic dysregulation of ACE2 and interferon-regulated genes might suggest increased COVID-19 susceptibility and severity in lupus patients.
Amr H. Sawalha;Ming Zhao;Patrick Coit;Qianjin Lu.
Clinical Immunology (2020)
COVID-19: A review of therapeutic strategies and vaccine candidates.
Vladislav Izda;Matlock A. Jeffries;Matlock A. Jeffries;Amr H. Sawalha.
Clinical Immunology (2021)
Identification of Multiple Genetic Susceptibility Loci in Takayasu Arteritis
Güher Saruhan-Direskeneli;Travis Hughes;Kenan Aksu;Gokhan Keser.
American Journal of Human Genetics (2013)
Impaired DNA methylation and its mechanisms in CD4(+)T cells of systemic lupus erythematosus.
Yiqun Zhang;Ming Zhao;Amr H. Sawalha;Bruce Richardson.
Journal of Autoimmunity (2013)
Impaired T Cell Protein Kinase Cδ Activation Decreases ERK Pathway Signaling in Idiopathic and Hydralazine-Induced Lupus
Gabriela Gorelik;Jing Yuan Fang;Ailing Wu;Amr H. Sawalha.
Journal of Immunology (2007)
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