D-Index & Metrics Best Publications

D-Index & Metrics

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Immunology D-index 58 Citations 8,684 129 World Ranking 1871 National Ranking 921

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Internal medicine
  • Disease

His scientific interests lie mostly in Immunology, DNA methylation, Systemic lupus erythematosus, Epigenetics and Genetics. Amr H. Sawalha has researched Immunology in several fields, including Single-nucleotide polymorphism and Genetic predisposition. His Single-nucleotide polymorphism course of study focuses on Haplotype and Candidate gene.

His DNA methylation research integrates issues from Molecular biology and Methylation. He combines subjects such as T cell and Interferon with his study of Systemic lupus erythematosus. Epigenetics is a primary field of his research addressed under Gene.

His most cited work include:

  • Changes in the pattern of DNA methylation associate with twin discordance in systemic lupus erythematosus (497 citations)
  • Genome-wide DNA methylation study suggests epigenetic accessibility and transcriptional poising of interferon-regulated genes in naïve CD4+ T cells from lupus patients (203 citations)
  • Genome-wide DNA methylation patterns in CD4+ T cells from patients with systemic lupus erythematosus (177 citations)

What are the main themes of his work throughout his whole career to date?

His primary scientific interests are in Immunology, Systemic lupus erythematosus, Genetics, DNA methylation and Epigenetics. His Immunology research incorporates themes from Single-nucleotide polymorphism and Disease, Genetic predisposition. His Systemic lupus erythematosus research incorporates elements of Interferon, Autoimmunity, Malar rash and Rheumatology.

His work carried out in the field of DNA methylation brings together such families of science as Molecular biology, Cancer research and Methylation. His Epigenetics study combines topics in areas such as Epigenomics, Histone, microRNA and Pathogenesis. His studies deal with areas such as Genotyping and Candidate gene as well as Genetic association.

He most often published in these fields:

  • Immunology (82.26%)
  • Systemic lupus erythematosus (50.00%)
  • Genetics (49.60%)

What were the highlights of his more recent work (between 2018-2021)?

  • Systemic lupus erythematosus (50.00%)
  • Cancer research (18.15%)
  • Epigenetics (35.89%)

In recent papers he was focusing on the following fields of study:

Amr H. Sawalha spends much of his time researching Systemic lupus erythematosus, Cancer research, Epigenetics, Immunology and DNA methylation. His Systemic lupus erythematosus research includes elements of Hydroxychloroquine, Coronavirus disease 2019, Proinflammatory cytokine, Lupus nephritis and Autoimmunity. His Cancer research research is multidisciplinary, incorporating perspectives in Chromatin, EZH2, Cell type and GPNMB.

The study incorporates disciplines such as Interferon and Methylation in addition to DNA methylation. The Methylation study combines topics in areas such as Ankylosing spondylitis, Single-nucleotide polymorphism and HLA-B. Gene is a subfield of Genetics that Amr H. Sawalha tackles.

Between 2018 and 2021, his most popular works were:

  • Epigenetic dysregulation of ACE2 and interferon-regulated genes might suggest increased COVID-19 susceptibility and severity in lupus patients. (106 citations)
  • Inhibition of EZH2 prevents fibrosis and restores normal angiogenesis in scleroderma (30 citations)
  • Coronavirus Disease-2019: Implication for the care and management of patients with systemic lupus erythematosus. (20 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Internal medicine
  • Cancer

Immunology, Epigenetics, DNA methylation, Cancer research and Systemic lupus erythematosus are his primary areas of study. The Immune system research Amr H. Sawalha does as part of his general Immunology study is frequently linked to other disciplines of science, such as Viral entry, therefore creating a link between diverse domains of science. As part of one scientific family, Amr H. Sawalha deals mainly with the area of Epigenetics, narrowing it down to issues related to the Allele, and often CpG site, Single-nucleotide polymorphism, Ankylosing spondylitis and Methylation.

As part of his inquiry into Gene and Genetics, he is doing DNA methylation research. His Cancer research study incorporates themes from Chromatin, GPNMB, Locus and Chromosome conformation capture. His biological study spans a wide range of topics, including Tumor necrosis factor alpha, Hydroxychloroquine, Cytokine storm, Coronavirus disease 2019 and Viremia.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Changes in the pattern of DNA methylation associate with twin discordance in systemic lupus erythematosus

Biola M. Javierre;Agustin F. Fernandez;Julia Richter;Fatima Al-Shahrour.
Genome Research (2010)

613 Citations

Genome-wide DNA methylation study suggests epigenetic accessibility and transcriptional poising of interferon-regulated genes in naïve CD4+ T cells from lupus patients

Patrick Coit;Matlock Jeffries;Nezam Altorok;Mikhail G. Dozmorov.
Journal of Autoimmunity (2013)

229 Citations

Genetic association of interleukin-21 polymorphisms with systemic lupus erythematosus.

Amr H Sawalha;Amr H Sawalha;Amr H Sawalha;Kenneth M Kaufman;Kenneth M Kaufman;Kenneth M Kaufman;Jennifer A Kelly;Adam J Adler.
Annals of the Rheumatic Diseases (2007)

210 Citations

Genome-wide DNA methylation patterns in CD4+ T cells from patients with systemic lupus erythematosus

Matlock A. Jeffries;Mikhail Dozmorov;Yuhong Tang;Joan T. Merrill.
Epigenetics (2011)

192 Citations

Impaired T Cell Protein Kinase Cδ Activation Decreases ERK Pathway Signaling in Idiopathic and Hydralazine-Induced Lupus

Gabriela Gorelik;Jing Yuan Fang;Ailing Wu;Amr H. Sawalha.
Journal of Immunology (2007)

156 Citations

Impaired DNA methylation and its mechanisms in CD4(+)T cells of systemic lupus erythematosus.

Yiqun Zhang;Ming Zhao;Amr H. Sawalha;Bruce Richardson.
Journal of Autoimmunity (2013)

150 Citations

Identification of Multiple Genetic Susceptibility Loci in Takayasu Arteritis

Güher Saruhan-Direskeneli;Travis Hughes;Kenan Aksu;Gokhan Keser.
American Journal of Human Genetics (2013)

146 Citations

Common Variants within MECP2 Confer Risk of Systemic Lupus Erythematosus

Amr H. Sawalha;Amr H. Sawalha;Amr H. Sawalha;Ryan Webb;Shizhong Han;Jennifer A. Kelly.
PLOS ONE (2008)

145 Citations

Genome-wide DNA methylation study identifies significant epigenomic changes in osteoarthritic cartilage.

Matlock A. Jeffries;Madison Donica;Lyle W. Baker;Michael E. Stevenson.
Arthritis & Rheumatism (2014)

142 Citations

Identification of multiple independent susceptibility loci in the HLA region in Behçet's disease

Travis Hughes;Patrick Coit;Adam Adler;Vuslat Yilmaz.
Nature Genetics (2013)

141 Citations

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Profile was last updated on December 6th, 2021.
Research.com Ranking is based on data retrieved from the Microsoft Academic Graph (MAG).
The ranking d-index is inferred from publications deemed to belong to the considered discipline.

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