D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 71 Citations 15,372 163 World Ranking 4242 National Ranking 307

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • DNA
  • Cancer

His main research concerns Molecular biology, STAT protein, Transcription factor, STAT3 and STAT5. His Molecular biology research includes themes of Promoter, Transcription, Gene expression, Gene and Antibody. His STAT protein research integrates issues from STAT4 and Transactivation.

His work deals with themes such as Hormone response element, Glucocorticoid receptor and Cell biology, which intersect with Transcription factor. His STAT3 study integrates concerns from other disciplines, such as Carcinogenesis and Cancer research. The various areas that Bernd Groner examines in his Cancer research study include Signal transduction and Epithelial cell differentiation.

His most cited work include:

  • Three-dimensional structure of the Stat3β homodimer bound to DNA (667 citations)
  • Functional interactions between Stat5 and the glucocorticoid receptor (618 citations)
  • Cloning and expression of Stat5 and an additional homologue (Stat5b) involved in prolactin signal transduction in mouse mammary tissue (484 citations)

What are the main themes of his work throughout his whole career to date?

Bernd Groner mainly investigates Molecular biology, Cancer research, Cell biology, STAT protein and Transcription factor. His biological study spans a wide range of topics, including Transcription, Gene, Transactivation, Receptor and Promoter. He has researched Cancer research in several fields, including Cancer cell, Mammary gland, Signal transduction, Fusion protein and Cytotoxic T cell.

His research integrates issues of Internal medicine, Stromal cell, Cellular differentiation and Endocrinology in his study of Cell biology. His study in STAT protein is interdisciplinary in nature, drawing from both STAT4, stat and STAT5. His Transcription factor study combines topics in areas such as Regulation of gene expression, General transcription factor and Tyrosine phosphorylation.

He most often published in these fields:

  • Molecular biology (37.21%)
  • Cancer research (29.65%)
  • Cell biology (23.84%)

What were the highlights of his more recent work (between 2009-2017)?

  • Cell biology (23.84%)
  • Cancer research (29.65%)
  • STAT3 (12.79%)

In recent papers he was focusing on the following fields of study:

His primary areas of study are Cell biology, Cancer research, STAT3, STAT protein and Cancer cell. His work carried out in the field of Cell biology brings together such families of science as Cytokine, stat, Suppressor of cytokine signaling 1 and SOX2, KLF4. His Cancer research research incorporates themes from Cell signaling, Signal transduction, Cancer stem cell, Stem cell and Breast cancer.

The study incorporates disciplines such as Gene knockdown, Tumor microenvironment, Immunology, Immune system and Cytotoxic T cell in addition to STAT3. Bernd Groner combines subjects such as JAK-STAT signaling pathway, STAT5 and Transactivation with his study of STAT protein. His studies in STAT5 integrate themes in fields like Metastatic breast cancer, Pathology, Molecular biology, Reporter gene and Tumor initiation.

Between 2009 and 2017, his most popular works were:

  • STAT3 Induction of miR-146b Forms a Feedback Loop to Inhibit the NF-κB to IL-6 Signaling Axis and STAT3-Driven Cancer Phenotypes (126 citations)
  • miR-212 and miR-132 are required for epithelial stromal interactions necessary for mouse mammary gland development. (125 citations)
  • Jak Stat signaling and cancer: Opportunities, benefits and side effects of targeted inhibition. (114 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Cancer
  • DNA

His primary scientific interests are in Cell biology, STAT3, Cell migration, STAT protein and Cancer stem cell. As a part of the same scientific study, Bernd Groner usually deals with the Cell biology, concentrating on Transplantation and frequently concerns with Endocrinology. The STAT3 study combines topics in areas such as Tumor microenvironment, Cancer research, Infiltration and Gene knockdown.

His work investigates the relationship between STAT protein and topics such as Breast cancer that intersect with problems in microRNA. His research in Cancer stem cell intersects with topics in CD44, Mammary tumor and Adult stem cell. His Signal transduction research is multidisciplinary, relying on both Carcinogenesis and Downregulation and upregulation.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Three-dimensional structure of the Stat3β homodimer bound to DNA

Stefan Becker;Bernd Groner;Christoph W. Müller.
Nature (1998)

1013 Citations

Functional interactions between Stat5 and the glucocorticoid receptor

Elisabeth Stöcklin;Manuela Wissler;Fabrice Gouilleux;Bernd Groner.
Nature (1996)

796 Citations

Cloning and expression of Stat5 and an additional homologue (Stat5b) involved in prolactin signal transduction in mouse mammary tissue

Xiuwen Liu;Gertraud W. Robinson;Fabrice Gouilleux;Bernd Groner.
Proceedings of the National Academy of Sciences of the United States of America (1995)

649 Citations

STAT-related transcription factors are constitutively activated in peripheral blood cells from acute leukemia patients

Valerie Gouilleux-Gruart;Fabrice Gouilleux;Corinne Desaint;Jean-Francois Claisse.
Blood (1996)

403 Citations

Prolactin and glucocorticoid hormones synergistically induce expression of transfected rat beta-casein gene promoter constructs in a mammary epithelial cell line.

Wolfgang Doppler;Bernd Groner;Roland K. Ball.
Proceedings of the National Academy of Sciences of the United States of America (1989)

329 Citations

p300/CREB-Binding Protein Enhances the Prolactin-Mediated Transcriptional Induction through Direct Interaction with the Transactivation Domain of Stat5, but Does Not Participate in the Stat5-Mediated Suppression of the Glucocorticoid Response

Edith Pfitzner;Ruth Jähne;Manuela Wissler;Elisabeth Stoecklin.
Molecular Endocrinology (1998)

326 Citations

Deletion of the carboxyl-terminal transactivation domain of MGF-Stat5 results in sustained DNA binding and a dominant negative phenotype.

R Moriggl;V Gouilleux-Gruart;R Jähne;S Berchtold.
Molecular and Cellular Biology (1996)

324 Citations

Cytotoxic T lymphocytes with a grafted recognition specificity for ERBB2-expressing tumor cells.

Dirk Moritz;Winfried Wels;Jurgen Mattern;Bernd Groner.
Proceedings of the National Academy of Sciences of the United States of America (1994)

315 Citations

Ha-ras oncogene expression directed by a milk protein gene promoter: tissue specificity, hormonal regulation, and tumor induction in transgenic mice.

Anne-Catherine Andres;Cora-Ann Schonenberger;Bernd Groner;Lothar Hennighausen.
Proceedings of the National Academy of Sciences of the United States of America (1987)

289 Citations

Selective Inhibition of Tumor Cell Growth by a Recombinant Single-Chain Antibody-Toxin Specific for the erbB-2 Receptor

Winfried Wels;Ina-Maria Harwerth;Marcel Mueller;Bernd Groner.
Cancer Research (1992)

277 Citations

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